What's the difference between anaplastic and histogenetic?
Anaplastic
Definition:
(a.) Of or pertaining to anaplasty.
Example Sentences:
(1) The diagnosis of anaplastic thyroid cancer, though suspected, was deferred for permanent sections in all cases.
(2) In comparison to the well-differentiated ependymomas, the anaplastic form of this tumor exhibited a generally higher capacity to specifically bind the neoglycoproteins, containing alpha- or beta-glucosides.
(3) The other is more anaplastic, assoicated with a loss of reticular fibers surrounding the cells and an alveolar arrangement.
(4) The results obtained indicated that CEA may be used as a marker for tumour progression up to the point of malignant transformation, after which the selection for anaplastic variants during continuous in vitro culture may result in the subsequent reduction of cell membrane CEA expression.
(5) Moreover, S-phase prolongation was observed with the malignant changes, and the cell cycle time did not differ markedly among normal epithelium (22.8 hr), anaplastic epithelium (23.0 hr), and frank invasive carcinoma (26.1 hr).
(6) Based on the histological and immunohistochemical examination the tumors were differentiated as Burkitt's lymphoma (n = 1), as anaplastic large cell (ALC) lymphoma of the B-cell type (n = 1), as high-grade non-Hodgkin's lymphoma not classifiable according to the Kiel classification (n = 1), as immunoblastic-plasmoblastic lymphoma (n = 1), and as centroblastic lymphoma (n = 1).
(7) Electron microscopy of two cases of anaplastic giant cell tumor of the thyroid revealed that these neoplasms consisted of pleomorphic cells with large, bizarre-shaped nuclei and relatively little cytoplasm rich in rough endoplasmic reticulum.
(8) The median survival of all patients was 15 months, of glioblastoma (n = 41) 5.1 months, of anaplastic astrocytoma (n = 29) 12.4 months, of benign grade I-II astrocytoma (n = 30) 93.5 months, of other glioma 82.9 months (n = 27), and of probable glioma 9.8 months (n = 19); 22 patients are still alive 8.9-11.9 years after diagnosis.
(9) However, no such arrays were found in the plasma membranes of anaplastic glioma or glioblastoma tissues.
(10) Both large and small-cell anaplastic patients had significantly depressed lymphocyte proliferation by mitogens and allogeneic cells.
(11) The other 2 cases were identified as epidermoid carcinoma or anaplastic carcinoma as desmosome and tonofilaments were found.
(12) This is unlike DAB-1 and DAB-2 which showed poorly differentiated trabecular or anaplastic carcinomatous patterns.
(13) The predominant picture in the three cases was that of a mucinous cystic tumor, but small nodules of solid anaplastic carcinoma were found in all three cases.
(14) Of 874 morphologically classified tumours, squamous cell composed 45%, undifferentiated large cell 17%, small cell anaplastic 14%, adenocarcinoma 19%, carcinoid 2% and others 3%.
(15) Contact area for the continuous dog-kidney cell line MDCK was larger than that of either the leukemic blood cell RBL-1 or the anaplastic human colon cell HCT-15.
(16) However, while partially retaining their secretory capability, the anaplastic cells progressively lose their capacity to synthetize basal lamina and develop complex cellular attachments.
(17) The 2-year survival rates were 36% for anaplastic gliomas and 16% for glioblastomas.
(18) Many of the tumor cells were only slightly atypical but careful examination revealed at least some significantly anaplastic cells in every case, the degree of cellular atypia tending to parallel the depth of invasion.
(19) The patterns of immunoreactivity of large cell anaplastic lymphoma were similar, except that none was positive with B-cell antibodies and three were positive with T-cell antibodies.
(20) Reported is the case of a 70-year-old woman who, on diagnosis, was found to have a papillary carcinoma of the thyroid gland that showed an anaplastic transformation of a metastatic lesion of the right cervical lymph node.
Histogenetic
Definition:
(a.) Tissue-producing; connected with the formation and development of the organic tissues.
Example Sentences:
(1) A study of 77 cases of molluscum contagiosum implicates folliclular neogenesis as a primary histogenetic determinant.
(2) The present study was directed towards the characterization of cell-specific histogenetic markers for the various epithelial elements of the adult and the developing guinea pig submandibular salivary gland.
(3) Histoprognostic criterions according to Clark and Mihm were the histogenetic type, the level of invasion plus vascular embolic neoplastic invasion and the notion of mitotic index.
(4) The presence in the tumour of cells-hybrids possessing the two differentiations allows one to suppose a histogenetic link of this tumours with pluripotential cells of neuroectoderm.
(5) The histogenetic pattern of the dorsal and ventral retinal halves was different at the three time points investigated, i.e.
(6) This histogenetic hypothesis could account for the highly favorable evolution of some cases which were reported as synovialo-sarcoma.
(7) The localization of membrane-bound gamma-glutamyltransferase with monoclonal antibody (mAb) 138H11 proved to be of value for differential diagnosis of renal cancer, since it correlated with the histogenetic profile of human epithelial renal tumors.
(8) The histogenetic and oncogenetic implications of this neoplasm are briefly discussed.
(9) However, it is evident that the tumour cells react less than the epidermis to both the G1 and the G2 chalone, and thus the findings of this study do not provide any evidence against the theory that epidermoid transplanted tumours are less sensitive to epidermal chalones than normal tissue of the same histogenetic origin.
(10) In view of the fact that histogenetic independence of stromal and hemopoietic elements has been proved, there is no need any more for the generalizing term "reticulosis".
(11) When culture continued for 48--72 h, the cells underwent supercontraction and became non-viable, suggesting that the terminally differentiated adult myocardial cells are incapable of regenerating constituents obligatory for histogenetic reconstruction.
(12) The examination had histogenetical and taxonomic values in medulloblastoma (CNS neuroblastoma and mixed tumours with a component featuring primitive neuroectodermal or neuroblastic differentiation).
(13) Based on (1) the histogenetic-embryologic classification of germ cell tumors and the concept of yolk sac tumor (or endodermal sinus tumor), (2) the available clinical and experimental observations, and (3) the immunofluorescent localization of AFP in the endodermal sinus tumor of the human testis, it is concluded that AFP synthesis in these neoplasms is explained by the fact that they contain yolk sac endoderm, which produce AFP analogous with the physiological AFP synthesis by the fetal yolk sac in early embryogenesis.
(14) Comparison of changing incidence, sex distribution, site, histogenetic type, tumour thickness, and prognosis of all primary cutaneous melanomas in patients aged 65 and over diagnosed in Scotland in the 11 years 1979-89 with similar data for patients aged under 65.
(15) Polyclonal antibodies against osteonectin, a 32 kd non-collagenous bone protein, were applied for the histogenetic identification of variously differentiated osteosarcoma tissues.
(16) The histogenetic relationship to congenital mesoblastic nephroma, Wilms tumor and other tumors is discussed.
(17) The clinical, histological and histogenetic aspects of naevus follicularis keratosus (NFK) ("naevus comedonicus") are reported.
(18) Their origin from the angiomatosis is suggested by the sequence of the lesions and for topical and histogenetic reasons.
(19) A wide range of tumors were immunohistochemically analyzed for alpha-1-antitrypsin (AAT) and lysozyme in order to evaluate their specificity as histiocytic markers and their significance in the diagnostic and histogenetic evaluation of fibrohistiocytic tumors.
(20) The hypothetical histogenetic relationship of both neoplasms is discussed taking together the evidence collected in the very few similar cases on record.