(n.) A iron instrument which is attached to a ship by a cable (rope or chain), and which, being cast overboard, lays hold of the earth by a fluke or hook and thus retains the ship in a particular station.
(n.) Any instrument or contrivance serving a purpose like that of a ship's anchor, as an arrangement of timber to hold a dam fast; a contrivance to hold the end of a bridge cable, or other similar part; a contrivance used by founders to hold the core of a mold in place.
(n.) Fig.: That which gives stability or security; that on which we place dependence for safety.
(n.) An emblem of hope.
(n.) A metal tie holding adjoining parts of a building together.
(n.) Carved work, somewhat resembling an anchor or arrowhead; -- a part of the ornaments of certain moldings. It is seen in the echinus, or egg-and-anchor (called also egg-and-dart, egg-and-tongue) ornament.
(n.) One of the anchor-shaped spicules of certain sponges; also, one of the calcareous spinules of certain Holothurians, as in species of Synapta.
(v. t.) To place at anchor; to secure by an anchor; as, to anchor a ship.
(v. t.) To fix or fasten; to fix in a stable condition; as, to anchor the cables of a suspension bridge.
(v. i.) To cast anchor; to come to anchor; as, our ship (or the captain) anchored in the stream.
(v. i.) To stop; to fix or rest.
(n.) An anchoret.
Example Sentences:
(1) The haplotype of the recombinant X chromosome of each of 241 backcross progeny has been established using the X-linked anchor loci Otc, Hprt, Dmd, Pgk-1, and Amg and the additional probes DXSmh43 and Cbx-rs1.
(2) The popularly used procedure in Great Britain is that in which a sheet of Ivalon sponge is sutured to the sacrum and wrapped around the rectum thus anchoring it in place.
(3) The company also confirmed on Thursday as it launched its sports pay-TV offering at its new broadcasting base in the Olympic Park in Stratford, east London, that former BBC presenter Jake Humphrey will anchor its Premier League coverage.
(4) Since the introduction of osseointegrated titanium implants for bone-anchored facial and dental prostheses, an increasing number of irradiated patients are being treated with this technique.
(5) The brain enzyme did not contain components characteristic of the glycolipid anchors of erythrocyte acetylcholinesterases.
(6) Our findings support the proposal that bcd transcripts are selectively recognized and trapped as they enter the anterior tip of the oocyte, and suggest that this localization process is mediated by anchored sequence-specific receptors in the oocyte cytoplasm.
(7) Sanders, the Vermont senator and self-described democratic socialist, first answered questions from Fox News anchor Bret Baier over his comments in Sunday’s debate that white people “don’t know what it’s like to be living in a ghetto”.
(8) A truncated anchor-minus form of the G2 glycoprotein was found to be secreted into the culture medium, but was retained in the Golgi complex when coexpressed with the G1 glycoprotein.
(9) Major histocompatibility complex (MHC) class 1 molecules that were either transmembrane- (H-2Db) or glycosylphosphatidylinositol (GPI)-anchored (Qa2) were labeled with antibody-coated gold particles and moved across the cell surface with a laser optical tweezers until they encountered a barrier, the barrier-free path length (BFP).
(10) This lipid has a hybrid nature of an archaeal feature in alkyl glycerol diether core portion and an eucaryal feature in the polar head group identical to the conserved core structure (GlcNp(alpha 1-6)-myo-inositol 1-phosphate) of glycosylated phosphatidylinositol which serves as a membrane protein anchor in eucaryal cells.
(11) Ultrastructurally these glands had apical microvilli with associated glycocalyx and long anchoring rootlets.
(12) This was confirmed by the crystal structures, which also showed that the Gln46 amide is hydrogen bonded to the Phe100 N and O atoms, and tightly anchored in this position.
(13) Each of the two chemically identical subunits folds into a three-layer domain anchored by a large six-stranded mixed beta sheet.
(14) A group of proteins anchored to the cell by phosphatidylinositol (PI) has recently been identified.
(15) In conclusion, the N-linked sugar chains are not required for in vitro activity but required for in vivo activity, acting as anchors for the essential terminal sialic acids.
(16) Replacement of the COOH-terminal hydrophobic domain with a signal peptide that normally functions in membrane translocation, or with a random hydrophobic sequence, results in efficient and correct processing, producing GPI-anchored DAF on the cell surface.
(17) Since the corresponding keto analogue, N-[(R)-2-benzyl-5-cyano-4-oxopentanyl]-L-phenylalanine (compound 4), does not inactivate the enzyme, it is suggested that the NH in compound 1 is critical for the proper active-site anchoring of the inhibitor for the inactivation process to take place.
(18) Facebook Twitter Pinterest Donald Trump questions US citizenship of ‘anchor babies’.
(19) This tissue may anchor the lead so that it is difficult, dangerous, or impossible to remove it.
(20) The anchoring wire can also be retracted and repositioned.
Backbone
Definition:
(n.) The column of bones in the back which sustains and gives firmness to the frame; the spine; the vertebral or spinal column.
(n.) Anything like , or serving the purpose of, a backbone.
(n.) Firmness; moral principle; steadfastness.
Example Sentences:
(1) A method for the introduction of side chains containing isonitrile (isocyanide, functional group) on the backbone of polysaccharides and other hydroxylic polymers was developed.
(2) The chromophore of octopus rhodopsin is 11-cis retinal, linked via a protonated Schiff base to the protein backbone.
(3) An unprincipled coward with the backbone of an amoeba."
(4) The Pr(III)-induced shifts for several resolved nonexchangeable backbone proton resonances were compared with calculated shifts using the known x-ray structure.
(5) Here we present images of polydeoxyadenylate molecules aligned in parallel, with their bases lying flat on a surface of highly oriented pyrolytic graphite and with their charged phosphodiester backbones protruding upwards.
(6) These data suggest that the somnogenic actions of these lipid A analogs depend on the acylation or phosphorylation pattern and backbone structures of the molecules.
(7) The resulting family of structures has a mean backbone rmsd of 0.63 A (N, C alpha, C', O atoms), excluding the segments containing residues 45-59 and 84-88.
(8) wt polypeptide backbone, modified by an endoglycosidase F-sensitive carbohydrate moiety.
(9) The backbone dynamics of Ca(2+)-saturated recombinant Drosophila calmodulin has been studied by 15N longitudinal and transverse relaxation experiments, combined with 15N(1H) NOE measurements.
(10) A central eight-stranded beta-pleated sheet is the main feature of the polypeptide backbone folding in dihydrofolate reductase.
(11) To investigate the topochemical preference of backbone and side chains, unusual amino acids, including beta-methylphenylalanine7 or 11, beta-methyltryptophan8, as well as backbone modifications such as retro-inverso structures have been incorporated.
(12) The angle obtained for the C alpha-D resonance was consistent with a single-stranded beta 6.3-helical model for the backbone but not with double-helical models.
(13) In the holopeptide corticotropin, the side chain-side chain effects, as reflected by the titration curves obtained from variations in the aromatic region, support the idea of an helical organization of part of the backbone even in aqueous solution.
(14) The local secondary structure was calculated from sequential and medium-range backbone NOEs with the double-iterated Kalman filter method [Altman, R. B., & Jardetzky, O.
(15) Although the (n-h) plots predict the stereochemical possibility of both right-handed and left-handed helices, nucleic acids apparently prefer right-handed conformation because of the energetics associated with the sugar-phosphate backbone and the base.
(16) And 96% of our grants go to African organisations, universities, scientists and small businesses to achieve a single goal: reduce hunger and poverty on our continent by unleashing the potential of the millions of small, family farmers who are the backbone of African agriculture and African economies.
(17) In addition the bare central backbone showed transverse striations.
(18) Misfolded models were constructed by introducing incorrect side chains onto polypeptide backbones: side chains of the alpha-helical hemerythrin were modeled on the beta-sheeted backbone of immunoglobulin VL domain, whereas those of the VL domain were similarly modeled on the hemerythrin backbone.
(19) Complete assignments were obtained for the backbone 1H, 15N and 13C resonances, using three-dimensional heteronuclear 1H NOE 1H-15N multiple-quantum coherence spectroscopy (3D-NOESY-HMQC) and three-dimensional heteronuclear total correlation 1H-15N multiple-quantum coherence spectroscopy (3D-TOCSY-HMQC) experiments on 15N-enriched HPr and an additional three-dimensional triple-resonance 1HN-15N-13C alpha correlation spectroscopy (HNCA) experiment on 13C, 15N-enriched HPr.
(20) Teh presence of the polyglycerol phosphate backbone and fatty acid was required for maximum immunosuppression of the primary immunoglobulin M response to sheep cells.