(n.) A iron instrument which is attached to a ship by a cable (rope or chain), and which, being cast overboard, lays hold of the earth by a fluke or hook and thus retains the ship in a particular station.
(n.) Any instrument or contrivance serving a purpose like that of a ship's anchor, as an arrangement of timber to hold a dam fast; a contrivance to hold the end of a bridge cable, or other similar part; a contrivance used by founders to hold the core of a mold in place.
(n.) Fig.: That which gives stability or security; that on which we place dependence for safety.
(n.) An emblem of hope.
(n.) A metal tie holding adjoining parts of a building together.
(n.) Carved work, somewhat resembling an anchor or arrowhead; -- a part of the ornaments of certain moldings. It is seen in the echinus, or egg-and-anchor (called also egg-and-dart, egg-and-tongue) ornament.
(n.) One of the anchor-shaped spicules of certain sponges; also, one of the calcareous spinules of certain Holothurians, as in species of Synapta.
(v. t.) To place at anchor; to secure by an anchor; as, to anchor a ship.
(v. t.) To fix or fasten; to fix in a stable condition; as, to anchor the cables of a suspension bridge.
(v. i.) To cast anchor; to come to anchor; as, our ship (or the captain) anchored in the stream.
(v. i.) To stop; to fix or rest.
(n.) An anchoret.
Example Sentences:
(1) The haplotype of the recombinant X chromosome of each of 241 backcross progeny has been established using the X-linked anchor loci Otc, Hprt, Dmd, Pgk-1, and Amg and the additional probes DXSmh43 and Cbx-rs1.
(2) The popularly used procedure in Great Britain is that in which a sheet of Ivalon sponge is sutured to the sacrum and wrapped around the rectum thus anchoring it in place.
(3) The company also confirmed on Thursday as it launched its sports pay-TV offering at its new broadcasting base in the Olympic Park in Stratford, east London, that former BBC presenter Jake Humphrey will anchor its Premier League coverage.
(4) Since the introduction of osseointegrated titanium implants for bone-anchored facial and dental prostheses, an increasing number of irradiated patients are being treated with this technique.
(5) The brain enzyme did not contain components characteristic of the glycolipid anchors of erythrocyte acetylcholinesterases.
(6) Our findings support the proposal that bcd transcripts are selectively recognized and trapped as they enter the anterior tip of the oocyte, and suggest that this localization process is mediated by anchored sequence-specific receptors in the oocyte cytoplasm.
(7) Sanders, the Vermont senator and self-described democratic socialist, first answered questions from Fox News anchor Bret Baier over his comments in Sunday’s debate that white people “don’t know what it’s like to be living in a ghetto”.
(8) A truncated anchor-minus form of the G2 glycoprotein was found to be secreted into the culture medium, but was retained in the Golgi complex when coexpressed with the G1 glycoprotein.
(9) Major histocompatibility complex (MHC) class 1 molecules that were either transmembrane- (H-2Db) or glycosylphosphatidylinositol (GPI)-anchored (Qa2) were labeled with antibody-coated gold particles and moved across the cell surface with a laser optical tweezers until they encountered a barrier, the barrier-free path length (BFP).
(10) This lipid has a hybrid nature of an archaeal feature in alkyl glycerol diether core portion and an eucaryal feature in the polar head group identical to the conserved core structure (GlcNp(alpha 1-6)-myo-inositol 1-phosphate) of glycosylated phosphatidylinositol which serves as a membrane protein anchor in eucaryal cells.
(11) Ultrastructurally these glands had apical microvilli with associated glycocalyx and long anchoring rootlets.
(12) This was confirmed by the crystal structures, which also showed that the Gln46 amide is hydrogen bonded to the Phe100 N and O atoms, and tightly anchored in this position.
(13) Each of the two chemically identical subunits folds into a three-layer domain anchored by a large six-stranded mixed beta sheet.
(14) A group of proteins anchored to the cell by phosphatidylinositol (PI) has recently been identified.
(15) In conclusion, the N-linked sugar chains are not required for in vitro activity but required for in vivo activity, acting as anchors for the essential terminal sialic acids.
(16) Replacement of the COOH-terminal hydrophobic domain with a signal peptide that normally functions in membrane translocation, or with a random hydrophobic sequence, results in efficient and correct processing, producing GPI-anchored DAF on the cell surface.
(17) Since the corresponding keto analogue, N-[(R)-2-benzyl-5-cyano-4-oxopentanyl]-L-phenylalanine (compound 4), does not inactivate the enzyme, it is suggested that the NH in compound 1 is critical for the proper active-site anchoring of the inhibitor for the inactivation process to take place.
(18) Facebook Twitter Pinterest Donald Trump questions US citizenship of ‘anchor babies’.
(19) This tissue may anchor the lead so that it is difficult, dangerous, or impossible to remove it.
(20) The anchoring wire can also be retracted and repositioned.
Mainstay
Definition:
(n.) The stay extending from the foot of the foremast to the maintop.
(n.) Main support; principal dependence.
Example Sentences:
(1) Diuretics remain the mainstay of therapy for most hypertensive black patients.
(2) Surgery must be considered the mainstay of therapy for fibrosarcoma, but there is a need for adjunctive therapy.
(3) Although Burkitt's lymphoma (BL) can be treated by surgery, radiotherapy and immunotherapy, chemotherapy is the mainstay of treatment.
(4) Aggressive therapy with intravenous fluids and potassium and the judicious use of insulin, in conjunction with careful monitoring of central venous pressure and urine output, form the mainstays of treatment.
(5) CT is now the mainstay of diagnosis for stable patients with blunt hepatic injuries.
(6) Lubricants, anthralin, and corticosteroids form the mainstay of therapy in mild and moderate psoriasis of the palms and soles.
(7) Lithium remains the mainstay of pharmacologic therapy for the majority of patients with bipolar disorder; however, significant numbers of patients with both classical bipolar disorder and syndromal variants fail to respond to lithium therapy.
(8) Consequently, digoxin remains the mainstay for chronic inotropic support of the heart.
(9) Heparin is the mainstay of treatment for deep venous thrombosis and pulmonary embolism, with an important role played by warfarin therapy.
(10) Plain radiography remains the mainstay of diagnosis of vertebral injuries.
(11) Radiation rather than surgery has been the mainstay of treatment for intracranial tumors of the optic pathway.
(12) The mainstay of pain relief is effective use of analgetics which should be given orally if possible, on a regular schedule and on an individualized basis according with the WHO guidelines.
(13) The mainstays of therapy include motivation, meticulous physical and laboratory evaluation, abstinence, and support during withdrawal.
(14) Although combination antibiotic therapy and correct postoperative wound management are potentially successful, the mainstay of treatment is complete excision of all necrotic tissue.
(15) Pelviscopy, along with the entire concept of minimally invasive surgery through endoscopically guided intra-abdominal surgery, has become a mainstay in gynecologic surgery.
(16) Contact was made with a ‘mystical-religious’ group that used the gas to accelerate arriving at their transcendental-meditative state of choice.” It increased in popularity with the rise of festival culture – it’s been a mainstay of Glastonbury’s stone circle and squat parties in Bristol and south London for at least a decade – but the equipment needed to dispense it remained relatively expensive.
(17) Antipsychotic medication remains a mainstay of treatment in both acute and chronic schizophrenia.
(18) In all cases, even when corticosteroids are the mainstay of maintenance treatment, bronchodilators must be used simultaneously.
(19) For many centuries antacids have been the mainstay of treatment of peptic disorders.
(20) The mainstays of treatment are life-style changes to avoid overexertion and use of light-weight orthoses and assistive aids to unload the extremities.