(n.) Extreme pain, either of body or mind; excruciating distress.
Example Sentences:
(1) This dilemma is at the heart of many people's anguished indecision over the wisdom of our action in Iraq.
(2) British MPs are deceiving themselves if they believe they do not bear some of the responsibility for the “terrible tragedy” unfolding in Syria, the former chancellor, George Osborne, said on Tuesday during an often anguished emergency debate in the House of Commons on the carnage being inflicted in eastern Aleppo.
(3) Infertility is, in all its forms, a most private, hidden anguish.
(4) Downing street – aware of the anguish of the families of these unconfirmed Britons – has privately expressed frustration at the cumbersome process of identification of the bodies following the killings last Friday.
(5) She said: "There has been a huge amount of anguish and endless discussion of what more could have been done to save this boy.
(6) As shown in an eponymous fly-on-the-wall documentary released earlier this year, Weiner refused to bow out of the race despite the anguish of his staff and Abedin, who often looked on in silence as her husband attempted to extricate himself from the scandal.
(7) The method to overcome the resistance to dental attention due to anguish is to establish a good relation-ship between the dentist and the patient, a good management of the ambivalent feeling of the child and the elimination of the phenomenon of transference.
(8) Some gifted and canny writers have made a mint by appealing to teenagers’ sense of anguish and victimhood, the notion that they are forever embattled and persecuted by a rotten world run by authoritarian bozos.
(9) A phenomenological approach permits to confirm the intuition of language in showing that the living experience of anguish is different from the one of anxiety.
(10) The anguish families experience when they are asked to make health care decisions for incompetent members has stimulated the search for adequate prior directives.
(11) It is a bizarre, fascinating, crazily over-the-top piece of self-portraiture which verges on self-vivisection, culminating in Kim's cracked performance of "Arirang", a Korean folk-song replete with anguish.
(12) This man’s anguish and his love for his children pour out of your image and it is [a] look that I saw in the faces of countless people as we took them from the boats.” Working on deadline, I lost track of the family.
(13) He spoke out after a survey of 23,000 women's views of their birth experience with the NHS revealed significant dissatisfaction, and sometimes anger and anguish.
(14) In my experience as a GP, I have learned that many people feel embarrassed and ashamed in telling a doctor about their mental anguish.
(15) EPA Gazza’s Italia 90 tears were but a trickling tributary compared with the Amazon of anguish unleashed by the shell-shocked hosts during their mortifying 7-1 loss to Germany.
(16) But Brief Encounter has survived such threats, because it is so well made, because Laura's voiceover narration is truly anguished and dreamy, because the music suckers all of us, and because Celia Johnson and Trevor Howard are perfect.
(17) Admission to a critical care unit often causes a great deal of distress and anguish, not only for the patient but also his or her family.
(18) It was hinted at this week by Adam Posen , retiring member of the Bank's monetary policy committee, in criticising his colleagues for their "anguished religious ethics" over quantitative easing.
(19) Yet the Brazilians who were photographed unleashing their sorrow on a cloudy, darkening evening, in scenes of anguish from Estádio Mineirão to Copacabana beach, were not mourning a massacre, atrocity or anything else that might seem to justify such infinite sadness.
(20) "I know these measures are very tough … I am acutely aware of the hardship and the anguish such sacrifices have caused for Greeks," said Venizelos, adding that the measures would save the state €6.5bn – the equivalent of 3% of GDP.
Mania
Definition:
(n.) Violent derangement of mind; madness; insanity. Cf. Delirium.
(n.) Excessive or unreasonable desire; insane passion affecting one or many people; as, the tulip mania.
Example Sentences:
(1) The most striking differences were observed on the factors: Psychopathic deviation, Mania, Schizophrenia greater than controls and social introversion lower than controls.
(2) The patients had met Research Diagnostic Criteria for major depressive episode and had no evidence of schizophrenia or mania.
(3) There was a fall of mean AVP excretion during mania, the magnitude of the fall being related to the increase of water throughput.
(4) Despite the presence of some side effects, such as easily controlled seizures (9%) and transient mania (6%), the results of this investigation support the use of cingulotomy as a potentially effective treatment for patients with severe and disabling obsessive-compulsive disorder.
(5) The purpose of the present study was to examine the effects of lithium, a drug which is now used rather widely in the treatment of acute mania and the prophylaxis of manic-depressive bipolar disorders, on the pituitary-gonadal function in the laboratory rat.
(6) The authors present a case of coexisting obsessive-compulsive disorder (OCD) and bipolar affective disorder in which the obsessive-compulsive symptoms disappeared during episodes of mania and reappeared during periods of depression.
(7) CSF CRH levels in mania, simple dementia, or anxiety or somatization disorder were not significantly different from the controls.
(8) The game was one of many celebrations around the country as Russia was gripped with Putin birthday mania on Wednesday.
(9) We suggest that a fundamental reconceptualization of both mania and depression as overactivated neural systems (either excitatory or inhibitory) could facilitate this conceptualization.
(10) Depression is a result of abnormalities lowering the normal steady-state concentration of methylbarinine, whereas mania results from an abnormal elevation of methylbarinine.
(11) Organic brain performance deficits and disturbances of sexual function are seen with both types of alcoholic jealousy mania.
(12) Mania usually represents one extreme of recurrent affective illness in patients with a genetic predisposition.
(13) Eight of them were schizophrenia, one was paranoid, and one was mania.
(14) Antidepressant drugs are effective in the acute treatment and prevention of depression only, and can even precipitate hypomanic or manic "switches," or "rapid cycling" between mania and depression.
(15) Because of the practical difficulties which arise in studying manic patients, a reproducible model for mania using human subjects would be a valuable adjunct to research in this condition.
(16) (3) 64 of the 908 patients (7.0%) admitted for depression switched to hypomania or mania.
(17) To evaluate the possible abnormality in MAO activity in affective disorders, blood platelet samples were obtained from 80 patients with mania and depression.
(18) Mixed mania (i.e., a manic syndrome accompanied by depressive symptoms) and its response to long-term preventive drug treatment was studied as part of a larger NIMH collaborative study.
(19) It's the kind of TV that makes for a wipe-your-weekend-plans box set: the ending of every crack-fix of an episode had me twitchily reaching for the remote to a muttered internal monologue of: "Next one, next one, now, now…" Danes carries the series as the bipolar CIA agent Carrie Mathison, whose furious vigilance is hard to distinguish from pathological mania as she investigates, and ultimately falls for, Sergeant Brody (Damian Lewis), a Marine who may or may not be a terrorist after eight years held captive by al-Qaida.
(20) The authors present a case of mania associated with the prolonged ingestion of large doses of L-dopa.