(n.) One of a class of compounds which may be regarded as amides in which more or less of the hydrogen has been replaced by phenyl.
Example Sentences:
(1) The compounds 1-3 in reaction with nicotine aldehyde or p-chlorobenzaldehyde were transformed into appropriate anilides of 2,3-epoxypropionic acid 4-9.
(2) The potency of L-valine as an inhibitor of Zea mays acetohydroxyacid synthase (AHAS) is increased more than 8000-fold on conversion to its N-phthalyl anilide derivative which is active at 2 microM.
(4) PGH synthase inhibitory activity was especially pronounced in the bis(p-hydroxy anilide) derivatives, even extending to succinamide and adipamide derivatives.
(5) The column resolved the enantiomers of phenylalanine anilide as detected by both UV absorption and potentiometric measurements and the recorded signals could be correlated with the concentration of phenylalanine anilide.
(6) Three newly synthesized benzoic acid derivatives (terephthalic acid anilides, chalcone carboxylic acid, and azobenzene carboxylic acid), with a certain structural similarity to retinoic acid, were examined for their retinoid-like bioactivity and their capacity to bind to cellular retinoid binding proteins.
(7) Vadocaine hydrochloride (2',4'-dimethyl-6'-methoxy-3-(2-methylpiperidyl)propionanilide+ ++ hydrochloride, OR K-242-HCl; INN: vadocaine) is an anilide derivative with antitussive and local anaesthetic action.
(8) The authors conclude that the presence of relatively high levels of aniline and fatty acid anilides in oil specimens collected during the epidemic in the two towns studied indicates a high probability of the current or prior presence of the etiologic agent of toxic oil syndrome.
(9) A series of 1,3-bis-anilides of 4-hydroxyisophthalic acid was prepared and investigated for antibacterial and antifungal activities.
(10) Iohexol and ioxilan both contain centers of potential isomerism stemming from the D,L hydroxyalkyls, the carbamoyl substituents, the alkylated anilide nitrogen and the acetylated anilide.
(11) Low concentration (10(-5)--10(-6) M) of either ATP, gamma-anilidate or GMP stimulates the aminoacylation of tRNA suggesting their interaction with some nucleotide binding sites of the enzyme other than catalytic ones.
(12) Mice treated with oleyl anilide, a putative toxic compound found in some stocks of the toxic rapeseed oil, did not present clinical or anatomical findings compatible with TOS.
(13) Recent data concerning the toxic actions of the anilides of oleic and linoleic acid are given.
(14) Infrared spectroscopy shows that these anilides exist in a single conformation, which exerts a powerful influence on the hydrogen-bond donor ability of the hydroxyl group in a model system.
(15) The naturally occurring anilides 1 and 3 had ID50 values of 0.10 and 0.27 mM, respectively.
(16) Fatty acid anilides, found in large amounts in adulterated cooking oil, were suspected to be the etiologic agent in this disease.
(17) These anilides have been detected as anomalous compound in toxic oils analysed.
(18) Values of Km were estimated to be 0.69 mM for anilide substrate and 0.33 mM for methylcoumarin substrate in the pyrrolidonyl peptidase reaction at pH 8.0.
(19) Substituted anilidates of uridine 5'-phosphate were synthesized and the stability of these amidates in anhydrous pyridine was studied.2'-O-Benzoyluridine 3'-phosphoranilidate and the corresponding beta-naphthylidate were compared in their stabilities in anhydrous pyridine, 50% aqueous pyridine and 80% acetic acid.
(20) After having demonstrated the impairment of the microsomal oxidation process in rats treated with toxic Spanish cooking oil or fatty acid anilides, we studied the possibility that the function of the cytoplasmic membrane had been affected.
Compound
Definition:
(n.) In the East Indies, an inclosure containing a house, outbuildings, etc.
(v. t.) To form or make by combining different elements, ingredients, or parts; as, to compound a medicine.
(v. t.) To put together, as elements, ingredients, or parts, in order to form a whole; to combine, mix, or unite.
(v. t.) To modify or change by combination with some other thing or part; to mingle with something else.
(v. t.) To compose; to constitute.
(v. t.) To settle amicably; to adjust by agreement; to compromise; to discharge from obligation upon terms different from those which were stipulated; as, to compound a debt.
(v. i.) To effect a composition; to come to terms of agreement; to agree; to settle by a compromise; -- usually followed by with before the person participating, and for before the thing compounded or the consideration.
(v. t.) Composed of two or more elements, ingredients, parts; produced by the union of several ingredients, parts, or things; composite; as, a compound word.
(n.) That which is compounded or formed by the union or mixture of elements ingredients, or parts; a combination of simples; a compound word; the result of composition.
(n.) A union of two or more ingredients in definite proportions by weight, so combined as to form a distinct substance; as, water is a compound of oxygen and hydrogen.
Example Sentences:
(1) These factors might account for the lower systemic bioavailability of these compounds.
(2) The interaction of the antibody with both the bacterial and the tissue derived polysialic acids suggests that the conformational epitope critical for the interaction is formed by both classes of compounds.
(3) These organic compounds were found to be stable on the sorbent tubes for at least seven days.
(4) Compound Z has the properties expected of an oxidized MPT precursor.
(5) Although Jeggo's Chinese hamster ovary cells were more responsive to mAMSA, novo still abrogated mAMSA toxicity in the mutant cells as well as in the parental Chinese hamster ovary cells 2,4-Dinitrophenol acted similarly to novo with respect to mAMSA killing, but neither compound reduced the ATP content of V79 cells.
(6) Recent data collected by the Games Outcomes Project and shared on the website Gamasutra backs up the view that crunch compounds these problems rather than solving them.
(7) There fore, the adverse effects may be induced by such quartz or silicon compounds.
(8) Fluorination with [18F]acetylhypofluorite yields 6-[18F]fluoro-L-dopa with 95% radiochemical purity; fluorination of the same substrate with [18F]F2 yields a mixture of all three structural isomers in a ratio of 70:16:14 for 6-, 5-, and 2-fluoro compounds.
(9) Mitonafide is the lead compound of a new series of antitumor drugs, the 3-Nitronaphthalimides, which have shown antineoplastic activity in vitro as well as in vivo.
(10) We have examined the activities of X, Y, and several related compounds as activators of macrophages.
(11) [125I]ET-1 binding to ETB receptors (nonselective to ET isopeptides) in cerebellar membranes was not inhibited by either of these compounds even at 100 microM.
(12) The individual classes of drugs are first treated separately to highlight specific aspects of their quantification, and this is followed by an overview of those methods permitting the concomitant analysis of two or more antiepileptic compounds.
(13) The remainder of the radioactivity appeared chromatographically just prior to the bisantrene peak, indicating that compounds more polar than the parent were present as transformation products.
(14) The ADAM derivative of carnitine was separated from decomposition products of the reagent and related compounds such as amino acid derivatives on a silica gel column eluted with methanol-5% aqueous SDS-phosphoric acid (990:10:1).
(15) Accidentally discovered nearly 40 years ago as the first true antidepressants, the MAOIs soon fell into disfavor due to concerns about toxicity and seemingly lesser efficacy compared with the newer tricyclic compounds.
(16) In a series of compounds with H2-antihistaminic activity, a conformational analysis was performed based on force field calculations.
(17) All three compounds were also very similar in their effects on [3H]5HT release from superfused rat striatal slices.
(18) A new compound, 5-bromo-2-(N,N-dimethylaminomethyl)furnan (IIc), is prepared in a similar way.
(19) On the basis of obtained data on the uniformity of chemical compounds of the secretion of glands belonging to different groups their common origin has been suggested.
(20) S-methyl-l-cysteine, 2-hydroxy-4-methiol butyric acid, S-adenosyl-l-methionine, and methionine peptides were the only compounds supporting growth, when substituted for methionine.