(n.) One of a class of compounds which may be regarded as amides in which more or less of the hydrogen has been replaced by phenyl.
Example Sentences:
(1) The compounds 1-3 in reaction with nicotine aldehyde or p-chlorobenzaldehyde were transformed into appropriate anilides of 2,3-epoxypropionic acid 4-9.
(2) The potency of L-valine as an inhibitor of Zea mays acetohydroxyacid synthase (AHAS) is increased more than 8000-fold on conversion to its N-phthalyl anilide derivative which is active at 2 microM.
(4) PGH synthase inhibitory activity was especially pronounced in the bis(p-hydroxy anilide) derivatives, even extending to succinamide and adipamide derivatives.
(5) The column resolved the enantiomers of phenylalanine anilide as detected by both UV absorption and potentiometric measurements and the recorded signals could be correlated with the concentration of phenylalanine anilide.
(6) Three newly synthesized benzoic acid derivatives (terephthalic acid anilides, chalcone carboxylic acid, and azobenzene carboxylic acid), with a certain structural similarity to retinoic acid, were examined for their retinoid-like bioactivity and their capacity to bind to cellular retinoid binding proteins.
(7) Vadocaine hydrochloride (2',4'-dimethyl-6'-methoxy-3-(2-methylpiperidyl)propionanilide+ ++ hydrochloride, OR K-242-HCl; INN: vadocaine) is an anilide derivative with antitussive and local anaesthetic action.
(8) The authors conclude that the presence of relatively high levels of aniline and fatty acid anilides in oil specimens collected during the epidemic in the two towns studied indicates a high probability of the current or prior presence of the etiologic agent of toxic oil syndrome.
(9) A series of 1,3-bis-anilides of 4-hydroxyisophthalic acid was prepared and investigated for antibacterial and antifungal activities.
(10) Iohexol and ioxilan both contain centers of potential isomerism stemming from the D,L hydroxyalkyls, the carbamoyl substituents, the alkylated anilide nitrogen and the acetylated anilide.
(11) Low concentration (10(-5)--10(-6) M) of either ATP, gamma-anilidate or GMP stimulates the aminoacylation of tRNA suggesting their interaction with some nucleotide binding sites of the enzyme other than catalytic ones.
(12) Mice treated with oleyl anilide, a putative toxic compound found in some stocks of the toxic rapeseed oil, did not present clinical or anatomical findings compatible with TOS.
(13) Recent data concerning the toxic actions of the anilides of oleic and linoleic acid are given.
(14) Infrared spectroscopy shows that these anilides exist in a single conformation, which exerts a powerful influence on the hydrogen-bond donor ability of the hydroxyl group in a model system.
(15) The naturally occurring anilides 1 and 3 had ID50 values of 0.10 and 0.27 mM, respectively.
(16) Fatty acid anilides, found in large amounts in adulterated cooking oil, were suspected to be the etiologic agent in this disease.
(17) These anilides have been detected as anomalous compound in toxic oils analysed.
(18) Values of Km were estimated to be 0.69 mM for anilide substrate and 0.33 mM for methylcoumarin substrate in the pyrrolidonyl peptidase reaction at pH 8.0.
(19) Substituted anilidates of uridine 5'-phosphate were synthesized and the stability of these amidates in anhydrous pyridine was studied.2'-O-Benzoyluridine 3'-phosphoranilidate and the corresponding beta-naphthylidate were compared in their stabilities in anhydrous pyridine, 50% aqueous pyridine and 80% acetic acid.
(20) After having demonstrated the impairment of the microsomal oxidation process in rats treated with toxic Spanish cooking oil or fatty acid anilides, we studied the possibility that the function of the cytoplasmic membrane had been affected.
Nitrogen
Definition:
(n.) A colorless nonmetallic element, tasteless and odorless, comprising four fifths of the atmosphere by volume. It is chemically very inert in the free state, and as such is incapable of supporting life (hence the name azote still used by French chemists); but it forms many important compounds, as ammonia, nitric acid, the cyanides, etc, and is a constituent of all organized living tissues, animal or vegetable. Symbol N. Atomic weight 14. It was formerly regarded as a permanent noncondensible gas, but was liquefied in 1877 by Cailletet of Paris, and Pictet of Geneva.
Example Sentences:
(1) These results are discussed in relation to the possible existence of enzyme-bound intermediates of nitrogen fixation.
(2) The measurement of the intestinal metabolism of the nitrogen moiety of glutamic acid has been investigated by oral ingestion of l-[15N]glutamic acid and sampling of arterialized blood.
(3) The induction of cells with two Y chromosomes by nitrogen mustard (NM) was examined.
(4) The disappearance of the herbicide, Avadex (40% diallate), from five agricultural soils (differing in either pH, carbon content, or nitrogen content), incubated under sterile and non-sterile conditions, was followed for a period of 20 weeks.
(5) Suspensions of isolated insect flight muscle thick filaments were embedded in layers of vitreous ice and visualized in the electron microscope under liquid nitrogen conditions.
(6) Airway closure (CV), functional residual capacity (FRC) and the distribution of inspired gas (nitrogen washout delay percentage, NWOD %) and arterial oxygen tension (PaO2) was measured by standard electrodes in eight extremely obese patients before and after weight loss (mean weights 142 and 94 kg, respectively) following intestinal shunt operation.
(7) Formula fed infants retained more nitrogen and gained weight faster.
(8) Triglyceride (Trigly) in female dogs, glutamic-pyruvic transaminase (GPT) and urea nitrogen (Urea-N) in male dogs tended to increase.
(9) Nitrogen retention was curvilinear in relation to metabolic live weight (kg0.75) in both series.
(10) Corynebacterium parvum-treated mice produce large amounts of circulating nitrogen oxides and develop a severe liver injury in response to lipopolysaccharide (LPS).
(11) Eight men and eight women each performed peak oxygen intake tests on a cycle ergometer breathing ambient air and a mixture of 12% oxygen in nitrogen (equivalent to an altitude of 4400 m) in the two experiments.
(12) From this, it was suggested that a negligible amount of oestradiol was released from these compounds and that the oestradiol moiety was useful as a carrier for the nitrogen mustard moiety.
(13) The intravenous administration of ovine placental lactogen to pregnant and non-pregnant sheep produced significant acute decreases in plasma free fatty acid, glucose and amino nitrogen concentrations.
(14) In contrast, nitrogen incubation did not alter the basal levels of TBA reactants except for a small rise associated with VE deficiency.
(15) MCT TPN was found to have some disadvantages, especially with regard to nitrogen balance and plasma albumin levels.
(16) Nitrogen mustard (N2M) treatment of rabbits induced neutropenia, and, in ligated ileal loops, it inhibited fluid secretion induced by salmonella or by cholera toxin (CT).
(17) For dipeptides containing the amino terminal residues glycine, alanine and phenylalanine, abstraction of the hydrogen from the carbon adjacent to the peptide nitrogen was the major process leading to the spin-adducts.
(18) The raw data are obtained by capillary gas chromatography using a nitrogen-phosphorus detector.
(19) Total protein, RNA, DNA, nitrogen, free amino acids and water content were determined in both lymphatic organs.
(20) This is the first evidence supporting carbon-nitrogen bond formation as the initial site of interaction between the two substrate molecules.