(n.) An organic base belonging to the phenylamines. It may be regarded as ammonia in which one hydrogen atom has been replaced by the radical phenyl. It is a colorless, oily liquid, originally obtained from indigo by distillation, but now largely manufactured from coal tar or nitrobenzene as a base from which many brilliant dyes are made.
(a.) Made from, or of the nature of, aniline.
Example Sentences:
(1) Pretreatment of rats with 6-(3-picolyl)amino-2,2,5,8-tetramethylchromane (PATC) for 7 days resulted in a significant increase in the activities of benzphetamine N-demethylase, p-nitroanisole O-demethylase and aniline hydroxylase in liver microsomes prepared 24 h after the last treatment.
(2) Comparison of the specific activities for aniline hydroxylation and p-nitrophenol hydroxylation of individual microsomal samples from control, ethanol-pretreated and phenobarbital-pretreated animals showed a high degree of correlation (r2 = 0.98) consistent with the involvement of the same site for catalysis of these two compounds.
(3) Chlordimeform had no effect on the cytochrome P-450 content, aniline p-hydroxylase or glutathione S-transferase activities, but induced ethoxyresorufin-O-deethylase, ethoxycoumarin-O-deethylase and epoxide hydrolase activities and decreased aldrin epoxidase and aminopyrine N-demethylase activities.
(4) Intestinal aniline hydroxylation was refractory to ethanol induction.
(5) Incubation of aniline-metabolizing hepatocytes with disulfiram resulted in decreased formation of 4-aminophenol, but this was not associated with impaired glucuronidation or cytochrome P-450 levels.
(6) At 20 degrees C, in a phosphate buffer, pH 5,8--8,0, methanol and aniline interactions with hemoglobin and cytochrome c were studied using the difference spectrophotometry method.
(7) Activities of amidopyrine N-demethylase, aniline hydroxylase, NADPH, cytochrome c reductase as well as content of cytochromes P-450 and b5 were studied in liver tissue of rats within 1, 3, 7, 10, 20 and 30 days of hypokinesia caused by maintaining of the animals in individual cell-cases.
(8) In contrast, menadione does not change the type II binding spectrum induced by aniline.
(9) Enzymatic polymerization took place on the surface of BOD-adsorbed solid matrix which was in contact with a buffer solution containing aniline.
(10) In NADPH-containing microsomal systems with 4-fluoro-substituted anilines, formation of the 4-hydroxyaniline derivative is observed because NADPH chemically reduces this quinoneimine metabolite.
(11) The activity of aniline hydroxylase was significantly increased in liver microsomes of EHBR whereas the activity of ethylmorphine N-demethylase was found to be significantly decreased in EHBR as compared to control rats.
(12) When compared to the first day, methemoglobin (MetHb) levels, measured prior to and following the exposure, increased with the days of exposure at 50 ppm aniline.
(13) Although metabolic attack occurred adjacent to either the aniline nitrogen or the aliphatic amine, metabolic attack occurred primarily adjacent to the more basic nitrogen at the 1'-position, even when this position bore a methyl substituent.
(14) Carbon monoxide inhibits the hydroxylase activity of the tissue-free system to a smaller extent than that of a system containing microsomes plus haemoglobin whereas p-chloromercuribenzoate inhibits only the flavoprotein-dependent hydroxylation of aniline mediated by haemoglobin.
(15) The profiles of urinary metabolites produced by rats and mice were not appreciably different in animals predosed with aniline.
(16) The results indicate that aniline degrading populations of these various microbial communities exhibit different activities probably depending on the extent of adaptation to pollutants to which the microbes are exposed.
(17) A high-pressure liquid chromatographic method has been developed for the determination of nanomole quantities of aniline; its metabolites o- and p-aminophenol, phenylhydroxylamine, nitrosobenzene and nitrobenzene; and azobenzene and azoxybenzene which form non-enzymatically by condensation of reactive metabolites.
(18) A series of ortho-quinone analogues 1-28 of podophyllotoxin possessing various C-4 beta-aniline moieties have been synthesized and evaluated for their inhibitory activity against human DNA topoisomerase II, their activity in causing cellular protein-linked DNA breakage, and their cytotoxicity against KB cells.
(19) The inhibitory effect of the nitroso-compound is demonstrated to be non-competitive on aminopyrine N-demethylase, p-nitroanisole O-demethylase and aniline hydroxylase.
(20) Compared with the control values, the levamisole treatment significantly increased the amount of cytochrome P450 and cytochrome b5 and the in-vitro activities of aminopyrine N-demethylase, benzphetamine N-demethylase and aniline hydroxylase.
Oily
Definition:
(superl.) Consisting of oil; containing oil; having the nature or qualities of oil; unctuous; oleaginous; as, oily matter or substance.
(superl.) Covered with oil; greasy; hence, resembling oil; as, an oily appearance.
(1) Wistar rats were infected by injection of 0.05 ml of a dense oily suspension of Staphylococcus aureus into the posterior thigh muscles of the hind leg.
(2) Nutritionists recommend we consume two portions a week of fish, including one of oily fish such as mackerel, herring and tuna.
(3) Our experience with these three patients, plus the two previously reported, suggest that two conditions must be present for oily material to enter the ventricular system through the outlets of the fourth ventricle: first, there must be a reversal of bulk flow of cerebrospinal fluid; second, the oily material must have a specific gravity less than that of cerebrospinal fluid.
(4) One group ate a diet high in saturated fat, salt and sugar, and low in fibre, oily fish and fruit and vegetables.
(5) Incubation of blood neutrophils with uterine flushings collected from ovariectomised mares treated with oestradiol, stimulated migration under agarose, whereas flushings from mares treated with progesterone or oily vehicle, inhibited migration.
(6) This characteristic of the oily contrast medium has been utilized for regional targeting of chemotherapy in patients with hepatocellular carcinoma, which has been termed "lipiodolization".
(7) CT scan and gamma camera radiograph confirmed that the oily contrast material or I-131 radioactivity accumulated selectively in the tumor over a long period.
(8) Of course we depend on oil companies because there is no other work.” Facebook Twitter Pinterest Canals full of oily water created during the cleanup process.
(9) The previous strict separation between water soluble, ionised media for the lumbal canal and oily media for the lumbosacral junction as well as the thoracic and cervical canal is no longer necessary.
(10) The many factors which affect absorption rate are discussed and it is suggested that preparations which depend on an oily gel to delay absorption add an avoidable factor to the list of variables which may play an important part in producing the significant differences in serum levels commonly reported after the use of PAM preparations.
(11) The figure includes around 29,000 deaths hastened by inhaling minute particles of oily, unburnt soot emitted by all petrol engines, and an estimated 23,500 by the invisible but toxic gas NO 2 emitted by diesel engines.
(12) Mackerel, an oily fish packed with Omega 3, has been championed by celebrity chefs such as Guardian writer Hugh Fearnley-Whittingstall, who in his Channel 4 Fish Fight programme persuaded sceptical consumers to eat his mackerel baps.
(13) The oily x-ray contrast medium persisted in the tumours over several weeks or months.
(14) "Lipiodol-Ultra-Fluid" an oily contrast medium which has used in experiments with minipigs can be radiologically and histologically demonstrated in nodes for months.
(15) Similar biological activities were obtained for oily and dry preparations of the same forms of alpha-tocopheryl acetate.
(16) The introduction of an oily retinylacetate solution into the fistula was attended both by an increase of the retinylpalmitate content in the blood plasma and the appearance therein of the retinyl-palmitat-hydrolase activity.
(17) Successful entrapment was achieved with the following conditions: (1) an alkaline water phase, (2) addition of fatty acid salt in the oily phase, and (3) addition of a water-miscible solvent in the oily phase.
(18) According to the British Heart Foundation, many doctors now prescribe fish oil supplements to reduce blood fats, although the BHF also recommends eating more oily fish.
(19) Forty-one CT sialograms were performed in 35 patients using acinar glandular filling with oily contrast material.
(20) Triglyceride is the major lipid class in most of these fishes with oily bones (74.1-93.7% as per cent lipid); cholesterol and phospholipid were two other lipid classes in the bones.