(n.) Opposition of action; counteraction or contrariety of things or principles.
Example Sentences:
(1) Intrathecal injection of zopiclone potentiated morphine antinociception, while the intracerebroventricular injection of zopiclone failed to enhance morphine antinociception and the intracerebroventricular injection of flumazepil to antagonize the intraperitoneal-zopiclone-induced increase in morphine antinociception.
(2) of PLA2 caused marked degranulation of mast cells in the rat mesentery which was facilitated by addition of calcium ion (10 mM) but antagonized by pretreating with three antiinflammatory agents.
(3) [Ca2+]i exhibited a sigmoidal dependence on [Na+]o. Mg2+, a competitive inhibitor of Na2+-Ca2+ antiport in these cells, antagonized the increase in [Ca2+]i produced by lowering [Na+]o.
(4) Increases in extracellular calcium antagonized the negative inotropic effect.
(5) In K+-depolarized basilar arteries, ifenprodil competitively antagonized the response to Ca2+, and this was enhanced by pre-incubation in calcium hopantenate.
(6) During the postovulatory phase, endogenous progesterone and the production of metabolites antagonized this effect.
(7) An antagonism is unlikely when ciprofloxacin is combined with one of the beta-lactams studied or with tobramycin.
(8) Co-application of CGS 9896, a benzodiazepine receptor antagonist, did not antagonize the guanidino compound-induced inhibition of GABA responses.
(9) Aortic rings from the rabbit were similarly potently antagonized by the protein kinase C inhibitors, however, K(+)-induced contractions were also equally sensitive to these agents in both rat and rabbit tissues.
(10) The biphasic response to (-)-(S)-Bay K 8644 and (+)-(S)-202-791 suggests that the properties of Ca++ channel activation and antagonism may reside within a single 1,4-dihydropyridine molecule.
(11) We have investigated the bacterial antagonism exerted in oral secretion by alpha-hemolytic streptococci against S. aureus and S. epidermidis.
(12) The marine natural product lophotoxin has produced a non-reversible antagonism of parasympathetic and sympathetic functions that are known to be mediated by C6 sub-type nicotinic receptors.
(13) Strains showing occasional antagonism at a particular proportion of concentrations of the test combination, were found to only be indifferent when the mean index of the fractional inhibition concentration of all checkerboard combinations was calculated.
(14) The omission of glucose induced a marked increase in the efflux of [3H]GABA, which was antagonized by TTX (1 microM), but not by MK 801 (1 microM) or DNQX (100 microM).
(15) The hyperthermia in rabbits caused by the serotonergic stimulants cited above is also antagonized by pretreatment with MS.
(16) The neuroleptic agents haloperidol, fluphenazine, domperidone, sulpiride and tiapride also antagonized emesis induced by cisplatin but only a proportion of the animals were completely protected and diazepam and prednisolone only reduced the intensity of the response.
(17) These results suggest that formoterol modifies allergen-induced airway responses through functional antagonism rather than the inhibition of inflammatory cell infiltration.
(18) Depolarizations induced by acetyl-Arg6-septide, a NK1-receptor selective agonist, were also antagonized by spantide with a pA2 of 6.5.
(19) 5-Hydroxytryptamine contracted the musculature from all parts of the respiratory tract-an effect which was specifically antagonized by both methysergide and atropine.4.
(20) K showed little activity against LTC4 but could antagonize more selectively H- and ACh-mediated effects.
Antagonize
Definition:
(v. t.) To contend with; to oppose actively; to counteract.
(v. i.) To act in opposition.
Example Sentences:
(1) Intrathecal injection of zopiclone potentiated morphine antinociception, while the intracerebroventricular injection of zopiclone failed to enhance morphine antinociception and the intracerebroventricular injection of flumazepil to antagonize the intraperitoneal-zopiclone-induced increase in morphine antinociception.
(2) of PLA2 caused marked degranulation of mast cells in the rat mesentery which was facilitated by addition of calcium ion (10 mM) but antagonized by pretreating with three antiinflammatory agents.
(3) [Ca2+]i exhibited a sigmoidal dependence on [Na+]o. Mg2+, a competitive inhibitor of Na2+-Ca2+ antiport in these cells, antagonized the increase in [Ca2+]i produced by lowering [Na+]o.
(4) Increases in extracellular calcium antagonized the negative inotropic effect.
(5) In K+-depolarized basilar arteries, ifenprodil competitively antagonized the response to Ca2+, and this was enhanced by pre-incubation in calcium hopantenate.
(6) During the postovulatory phase, endogenous progesterone and the production of metabolites antagonized this effect.
(7) An antagonism is unlikely when ciprofloxacin is combined with one of the beta-lactams studied or with tobramycin.
(8) Co-application of CGS 9896, a benzodiazepine receptor antagonist, did not antagonize the guanidino compound-induced inhibition of GABA responses.
(9) Aortic rings from the rabbit were similarly potently antagonized by the protein kinase C inhibitors, however, K(+)-induced contractions were also equally sensitive to these agents in both rat and rabbit tissues.
(10) The biphasic response to (-)-(S)-Bay K 8644 and (+)-(S)-202-791 suggests that the properties of Ca++ channel activation and antagonism may reside within a single 1,4-dihydropyridine molecule.
(11) We have investigated the bacterial antagonism exerted in oral secretion by alpha-hemolytic streptococci against S. aureus and S. epidermidis.
(12) The marine natural product lophotoxin has produced a non-reversible antagonism of parasympathetic and sympathetic functions that are known to be mediated by C6 sub-type nicotinic receptors.
(13) Strains showing occasional antagonism at a particular proportion of concentrations of the test combination, were found to only be indifferent when the mean index of the fractional inhibition concentration of all checkerboard combinations was calculated.
(14) The omission of glucose induced a marked increase in the efflux of [3H]GABA, which was antagonized by TTX (1 microM), but not by MK 801 (1 microM) or DNQX (100 microM).
(15) The hyperthermia in rabbits caused by the serotonergic stimulants cited above is also antagonized by pretreatment with MS.
(16) The neuroleptic agents haloperidol, fluphenazine, domperidone, sulpiride and tiapride also antagonized emesis induced by cisplatin but only a proportion of the animals were completely protected and diazepam and prednisolone only reduced the intensity of the response.
(17) These results suggest that formoterol modifies allergen-induced airway responses through functional antagonism rather than the inhibition of inflammatory cell infiltration.
(18) Depolarizations induced by acetyl-Arg6-septide, a NK1-receptor selective agonist, were also antagonized by spantide with a pA2 of 6.5.
(19) 5-Hydroxytryptamine contracted the musculature from all parts of the respiratory tract-an effect which was specifically antagonized by both methysergide and atropine.4.
(20) K showed little activity against LTC4 but could antagonize more selectively H- and ACh-mediated effects.