(n.) Opposition of action; counteraction or contrariety of things or principles.
Example Sentences:
(1) Intrathecal injection of zopiclone potentiated morphine antinociception, while the intracerebroventricular injection of zopiclone failed to enhance morphine antinociception and the intracerebroventricular injection of flumazepil to antagonize the intraperitoneal-zopiclone-induced increase in morphine antinociception.
(2) of PLA2 caused marked degranulation of mast cells in the rat mesentery which was facilitated by addition of calcium ion (10 mM) but antagonized by pretreating with three antiinflammatory agents.
(3) [Ca2+]i exhibited a sigmoidal dependence on [Na+]o. Mg2+, a competitive inhibitor of Na2+-Ca2+ antiport in these cells, antagonized the increase in [Ca2+]i produced by lowering [Na+]o.
(4) Increases in extracellular calcium antagonized the negative inotropic effect.
(5) In K+-depolarized basilar arteries, ifenprodil competitively antagonized the response to Ca2+, and this was enhanced by pre-incubation in calcium hopantenate.
(6) During the postovulatory phase, endogenous progesterone and the production of metabolites antagonized this effect.
(7) An antagonism is unlikely when ciprofloxacin is combined with one of the beta-lactams studied or with tobramycin.
(8) Co-application of CGS 9896, a benzodiazepine receptor antagonist, did not antagonize the guanidino compound-induced inhibition of GABA responses.
(9) Aortic rings from the rabbit were similarly potently antagonized by the protein kinase C inhibitors, however, K(+)-induced contractions were also equally sensitive to these agents in both rat and rabbit tissues.
(10) The biphasic response to (-)-(S)-Bay K 8644 and (+)-(S)-202-791 suggests that the properties of Ca++ channel activation and antagonism may reside within a single 1,4-dihydropyridine molecule.
(11) We have investigated the bacterial antagonism exerted in oral secretion by alpha-hemolytic streptococci against S. aureus and S. epidermidis.
(12) The marine natural product lophotoxin has produced a non-reversible antagonism of parasympathetic and sympathetic functions that are known to be mediated by C6 sub-type nicotinic receptors.
(13) Strains showing occasional antagonism at a particular proportion of concentrations of the test combination, were found to only be indifferent when the mean index of the fractional inhibition concentration of all checkerboard combinations was calculated.
(14) The omission of glucose induced a marked increase in the efflux of [3H]GABA, which was antagonized by TTX (1 microM), but not by MK 801 (1 microM) or DNQX (100 microM).
(15) The hyperthermia in rabbits caused by the serotonergic stimulants cited above is also antagonized by pretreatment with MS.
(16) The neuroleptic agents haloperidol, fluphenazine, domperidone, sulpiride and tiapride also antagonized emesis induced by cisplatin but only a proportion of the animals were completely protected and diazepam and prednisolone only reduced the intensity of the response.
(17) These results suggest that formoterol modifies allergen-induced airway responses through functional antagonism rather than the inhibition of inflammatory cell infiltration.
(18) Depolarizations induced by acetyl-Arg6-septide, a NK1-receptor selective agonist, were also antagonized by spantide with a pA2 of 6.5.
(19) 5-Hydroxytryptamine contracted the musculature from all parts of the respiratory tract-an effect which was specifically antagonized by both methysergide and atropine.4.
(20) K showed little activity against LTC4 but could antagonize more selectively H- and ACh-mediated effects.
Natural
Definition:
(a.) Fixed or determined by nature; pertaining to the constitution of a thing; belonging to native character; according to nature; essential; characteristic; not artifical, foreign, assumed, put on, or acquired; as, the natural growth of animals or plants; the natural motion of a gravitating body; natural strength or disposition; the natural heat of the body; natural color.
(a.) Conformed to the order, laws, or actual facts, of nature; consonant to the methods of nature; according to the stated course of things, or in accordance with the laws which govern events, feelings, etc.; not exceptional or violent; legitimate; normal; regular; as, the natural consequence of crime; a natural death.
(a.) Having to do with existing system to things; dealing with, or derived from, the creation, or the world of matter and mind, as known by man; within the scope of human reason or experience; not supernatural; as, a natural law; natural science; history, theology.
(a.) Conformed to truth or reality
(a.) Springing from true sentiment; not artifical or exaggerated; -- said of action, delivery, etc.; as, a natural gesture, tone, etc.
(a.) Resembling the object imitated; true to nature; according to the life; -- said of anything copied or imitated; as, a portrait is natural.
(a.) Having the character or sentiments properly belonging to one's position; not unnatural in feelings.
(a.) Connected by the ties of consanguinity.
(a.) Begotten without the sanction of law; born out of wedlock; illegitimate; bastard; as, a natural child.
(a.) Of or pertaining to the lower or animal nature, as contrasted with the higher or moral powers, or that which is spiritual; being in a state of nature; unregenerate.
(a.) Belonging to, to be taken in, or referred to, some system, in which the base is 1; -- said or certain functions or numbers; as, natural numbers, those commencing at 1; natural sines, cosines, etc., those taken in arcs whose radii are 1.
(a.) Produced by natural organs, as those of the human throat, in distinction from instrumental music.
(a.) Of or pertaining to a key which has neither a flat nor a sharp for its signature, as the key of C major.
(a.) Applied to an air or modulation of harmony which moves by easy and smooth transitions, digressing but little from the original key.
(n.) A native; an aboriginal.
(n.) Natural gifts, impulses, etc.
(n.) One born without the usual powers of reason or understanding; an idiot.
(n.) A character [/] used to contradict, or to remove the effect of, a sharp or flat which has preceded it, and to restore the unaltered note.
Example Sentences:
(1) The results indicated that neuropsychological measures may serve to broaden the concept of intelligence and that a brain-related criterion may contribute to a fuller understanding of its nature.
(2) In Patient 2 they were at first paroxysmal and unformed, with more prolonged metamorphopsia; later there appeared to be palinoptic formed images, possibly postictal in nature.
(3) We conclude that the priming effect is not a clinically significant phenomenon during natural pollen exposure in allergic rhinitis patients.
(4) Quantitative determinations indicate that the amount of PBG-D mRNA is modulated both by the erythroid nature of the tissue and by cell proliferation, probably at the transcriptional level.
(5) The severity and site of hypertrophy is important in determining the clinical picture and the natural history of hypertrophic cardiomyopathy (HCM).
(6) Here, we review the nature of the heart sound signal and the various signal-processing techniques that have been applied to PCG analysis.
(7) To investigate the immunomodulating properties of cis-diamminedichloroplatinum (II) (CDDP), we studied the drug's effects on natural killer (NK) lymphocyte cytotoxicity.
(8) Examined specific relationships, as they occur in nature, between particular dietary variables or groups of variables and specific MMPI subscales.
(9) Natural tubulin polymerization leads to the formation of hooks on microtubular structures.
(10) Trichostatin C is presumably the first example of a glucopyranosyl hydroxamate from nature.
(11) The present study was undertaken to find out the nature of enzymes responsible for the processing of DV antigen in M phi.
(12) The cyclical nature of pyromania has parallels in cycles of reform in standards of civil commitment (Livermore, Malmquist & Meehl, 1958; Dershowitz, 1974), in the use of physical therapies and medications (Tourney, 1967; Mora, 1974), in treatment of the chronically mentally ill (Deutsch, 1949; Morrissey & Goldman, 1984), and in institutional practices (Treffert, 1967; Morrissey, Goldman & Klerman (1980).
(13) The nature of the putative autoantigen in Graves' ophthalmopathy (Go) remains an enigma but the sequence similarity between thyroglobulin (Tg) and acetylcholinesterase (ACHE) provides a rationale for epitopes which are common to the thyroid gland and the eye orbit.
(14) Further exploration of these excretory pathways will provide interesting new insights on the numerous cholestatic and hyperbilirubinemic syndromes that occur in nature.
(15) In this way they offer the doctor the chance of preventing genetic handicaps that cannot be obtained by natural reproduction, and that therefore should be used.
(16) The nature, intracellular distribution, and role of proteins synthesized during meiotic maturation of mouse oocytes in vitro have been examined.
(17) Natural killer cells (CD8+CD57+) as well as activated T cells (CD3+HLA-DR+) were significantly increased in patients with sarcoidosis.
(18) In certain cases, the effects of these substances are enhanced, in others, they are inhibited by compounds that were isolated from natural sources or prepared by chemical synthesis.
(19) Analysis of 156 records relating to patients at the age of 15 to 85 years with extended purulent peritonitis of the surgical and gynecological genesis (the toxic phase, VI category ASA) showed that combination of programmed sanitation laparotomy and intensive antibacterial therapy performed as short-term courses before, during and after the operation with an account of the information on the nature of the microbial associations and antibioticograms was an efficient procedure in treatment of severe peritonitis.
(20) There is no convincing evidence that immunosuppression is effective, also because the natural history of the disease is characterised by a spontaneous disappearance of the factor VIII-C inhibitor.