What's the difference between antagonist and contendent?

Antagonist


Definition:

  • (n.) One who contends with another, especially in combat; an adversary; an opponent.
  • (n.) A muscle which acts in opposition to another; as a flexor, which bends a part, is the antagonist of an extensor, which extends it.
  • (n.) A medicine which opposes the action of another medicine or of a poison when absorbed into the blood or tissues.
  • (a.) Antagonistic; opposing; counteracting; as, antagonist schools of philosophy.

Example Sentences:

  • (1) This death is also dependent on the presence of chloride and is prevented with the non-selective EAA antagonist, kynurenic acid, but is not prevented by QA.
  • (2) Microionophoretically applied excitatory amino acids induced firing of extracellularly recorded single units in a tissue slice preparation of the mouse cochlear nucleus, and the similarly applied antagonist 2-amino-5-phosphonovalerate (2APV) was demonstrated to be a selective N-methyl-D-aspartate (NMDA) receptor antagonist.
  • (3) Meanwhile the efficiency of muscarinic antagonists in inhibition of tremor reaction induced by arecoline administration is associated with interaction between the drugs and the M2-subtype.
  • (4) The anticonvulsant properties of the endogenous excitatory amino acid antagonist, kynurenic acid (KYA), were studied in prepubescent and adult rats using the amygdaloid kindling model of epilepsy.
  • (5) A novel bicyclic prostaglandin analogue, (1S)-[1 alpha,2 alpha(Z),3 alpha,4 alpha]-7-[3-[(hexylthio)methyl]-7- oxabicyclo [2.2.1]hept-2-yl]-5-heptenoic acid ((-)-10), and its cogeners were found to be potent antagonists at the TxA2 receptor.
  • (6) This difference was abolished by exposure of the slices to propranolol, a beta-adrenergic receptor antagonist.
  • (7) The TxA2 antagonistic effects of KW-3635 were compared with that of daltroban in PRP from various animals species.
  • (8) In experiments performed to determine whether PtdIns(4,5)P2 hydrolysis induced by TRH may have been caused by the elevation of [Ca2+]i, the following results were obtained: the effect of TRH to decrease the level of PtdIns(4,5)P2 was not reproduced by the calcium ionophore A23187 or by membrane depolarization with 50 mM K+; the calcium antagonist TMB-8 did not inhibit the TRH-induced decrease in PtdIns(4,5)P2; and, most importantly, inhibition by EGTA of the elevation of [Ca2+]i did not inhibit the TRH-induced decrease in PtdIns(4,5)P2.
  • (9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
  • (10) Selective removal of endothelium had no effect on BK-induced contraction or the action of the antagonists.
  • (11) The second experiments entailed use of the nonspecific opiate antagonist, naloxone, as well as the specific delta antagonist, ICI 154,129, against seizures induced by icv-administered morphine, morphiceptin, DADL, or DSLET.
  • (12) These antagonists reverse NMDA-mediated long term influence in these brain areas.
  • (13) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
  • (14) Furthermore, the ability of a vasopressin antagonist to lower arterial pressure in NTS hypertensive rats was markedly attenuated by clonidine treatment.
  • (15) All of the serotonergic antagonists studied had additional effects on the response of the coronary artery to electrical stimulation or to norepinephrine.
  • (16) Their receptive fields comprise a temporally and spatially linear mechanism (center plus antagonistic surround) that responds to relatively low spatial frequency stimuli, and a temporally nonlinear mechanism, coextensive with the linear mechanism, that--though broad in extent--responds best to high spatial-frequency stimuli.
  • (17) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
  • (18) Addition in the cultures of 4-deoxypyridoxine, a potent antagonist of vitamin B6 coenzymes, concurrently with the mitogen, inhibits the induction of serine hydroxymethyltransferase.
  • (19) These results suggest that prevention of xenograft rejection using PAF-antagonist in association with other methods should be further investigated.
  • (20) The high concentrations of gonadotropins present in immature female rats by the end of the second week of life were suppressed by treatment with an antagonist against luteinizing hormone-releasing hormone (LHRH-A; Org.

Contendent


Definition:

  • (n.) An antagonist; a contestant.

Example Sentences:

  • (1) Duesberg contends that HIV is neither necessary nor sufficient to cause AIDS.
  • (2) It is contended that the latter is the main factor in its production as opposed to the more common external rotation variety.
  • (3) The truth is, some of these attacks would be leveled against any Republican presidential contender.
  • (4) What did surprise pundits was Hollywood's recognition of this unflinching Austrian film about ageing as a candidate for best picture, among such expected contenders as Steven Spielberg's Lincoln , Ben Affleck's Argo and Tom Hooper's Les Misérables .
  • (5) The mayor needs to be in parliament to challenge other contenders for the party's leadership, such as George Osborne and Theresa May.
  • (6) Defence lawyers contended that Saiful's testimony about the alleged sodomy, at a Kuala Lumpur condominium in 2008, was riddled with inconsistencies and the DNA evidence mishandled by investigators.
  • (7) Although Menzies, et al., report that survival rates are higher than previously expected and that in most cases the children's and parents' lives appear not to be excessively burdensome, the Working Group contends that there "continues to be ethical justification for selective treatment" of such newborns.
  • (8) Romney contends the president is a nice guy who has failed to make things better.
  • (9) Radiotherapy after limited resection of craniopharyngiomas has been advocated by some investigators while others contend radical resections by means of advanced surgical techniques afford better outcome of patients.
  • (10) Despite spanning more than 1,300 acres it will not, apparently, be a contender for the title of world's largest: that appears still to reside with the 47-stage Ramoji Film City in Hyderabad, India, as certified by Guinness World Records .
  • (11) Those seeking to stop the project contend that the $997m joint venture, signed in May 2010, did not undergo parliamentary scrutiny because it was concluded under the previous military regime.
  • (12) Although acquired immunodeficiency syndrome (AIDS) is clearly a public health threat, Beauchamp contends that the view that it is also a threat to the majority's values is a form of potentially counterproductive legal moralism.
  • (13) The author contends that changes in psychoanalytic theory are currently facilitating a more experiential view of the Rorschach.
  • (14) And he will contend, with a laugh, that therefore by any objective criteria, at 54, his career should be over already, while all the time doing everything in his power to prove the opposite.
  • (15) Scott Walker says building Canada border wall is a 'legitimate issue' Read more The governor, who is running well behind among the 17 contenders in the Republican White House race, sought to draw a distinction between his proposal and what he called Donald Trump’s “simplistic” idea on how to deal with an estimated 11 million illegal immigrants in the US.
  • (16) The prosecution contended that while that manoeuvre was lawful, his repeated use of a baton against her legs showed the officer had lost his self-control.
  • (17) It represents something of a vindication for Spielberg whose last high-minded awards contender, the first-world-war drama War Horse, failed to win anything at the last edition of either the Globes or the Oscars.
  • (18) Before we meet, I have to have a stern talk with myself about not mentioning the game last August in which all Arsenal fans will contend that Barton got new signing Gervinho sent off on his debut; he's had similarly abrasive encounters since with fellow midfielders, Karl Henry from Wolves and Norwich's Bradley Johnson, the latter earning him a three-match ban.
  • (19) With four matches to take the crown, a single strength can make the difference for the remaining contenders.
  • (20) It’s a massive inconvenience to have to check a laptop, and you can imagine that such a demand is met with resistance by air carriers, who are powerful lobbies.” US airlines have been lobbying the Trump administration to intervene in the Persian Gulf, where they have contended for years that the investments in three rapidly expanding airlines in the area – Etihad Airways, Qatar, and Emirates – constitute unfair government subsidies with which Delta, American and United cannot compete.

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