(n.) One who contends with another, especially in combat; an adversary; an opponent.
(n.) A muscle which acts in opposition to another; as a flexor, which bends a part, is the antagonist of an extensor, which extends it.
(n.) A medicine which opposes the action of another medicine or of a poison when absorbed into the blood or tissues.
(a.) Antagonistic; opposing; counteracting; as, antagonist schools of philosophy.
Example Sentences:
(1) This death is also dependent on the presence of chloride and is prevented with the non-selective EAA antagonist, kynurenic acid, but is not prevented by QA.
(2) Microionophoretically applied excitatory amino acids induced firing of extracellularly recorded single units in a tissue slice preparation of the mouse cochlear nucleus, and the similarly applied antagonist 2-amino-5-phosphonovalerate (2APV) was demonstrated to be a selective N-methyl-D-aspartate (NMDA) receptor antagonist.
(3) Meanwhile the efficiency of muscarinic antagonists in inhibition of tremor reaction induced by arecoline administration is associated with interaction between the drugs and the M2-subtype.
(4) The anticonvulsant properties of the endogenous excitatory amino acid antagonist, kynurenic acid (KYA), were studied in prepubescent and adult rats using the amygdaloid kindling model of epilepsy.
(5) A novel bicyclic prostaglandin analogue, (1S)-[1 alpha,2 alpha(Z),3 alpha,4 alpha]-7-[3-[(hexylthio)methyl]-7- oxabicyclo [2.2.1]hept-2-yl]-5-heptenoic acid ((-)-10), and its cogeners were found to be potent antagonists at the TxA2 receptor.
(6) This difference was abolished by exposure of the slices to propranolol, a beta-adrenergic receptor antagonist.
(7) The TxA2 antagonistic effects of KW-3635 were compared with that of daltroban in PRP from various animals species.
(8) In experiments performed to determine whether PtdIns(4,5)P2 hydrolysis induced by TRH may have been caused by the elevation of [Ca2+]i, the following results were obtained: the effect of TRH to decrease the level of PtdIns(4,5)P2 was not reproduced by the calcium ionophore A23187 or by membrane depolarization with 50 mM K+; the calcium antagonist TMB-8 did not inhibit the TRH-induced decrease in PtdIns(4,5)P2; and, most importantly, inhibition by EGTA of the elevation of [Ca2+]i did not inhibit the TRH-induced decrease in PtdIns(4,5)P2.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) Selective removal of endothelium had no effect on BK-induced contraction or the action of the antagonists.
(11) The second experiments entailed use of the nonspecific opiate antagonist, naloxone, as well as the specific delta antagonist, ICI 154,129, against seizures induced by icv-administered morphine, morphiceptin, DADL, or DSLET.
(12) These antagonists reverse NMDA-mediated long term influence in these brain areas.
(13) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
(14) Furthermore, the ability of a vasopressin antagonist to lower arterial pressure in NTS hypertensive rats was markedly attenuated by clonidine treatment.
(15) All of the serotonergic antagonists studied had additional effects on the response of the coronary artery to electrical stimulation or to norepinephrine.
(16) Their receptive fields comprise a temporally and spatially linear mechanism (center plus antagonistic surround) that responds to relatively low spatial frequency stimuli, and a temporally nonlinear mechanism, coextensive with the linear mechanism, that--though broad in extent--responds best to high spatial-frequency stimuli.
(17) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(18) Addition in the cultures of 4-deoxypyridoxine, a potent antagonist of vitamin B6 coenzymes, concurrently with the mitogen, inhibits the induction of serine hydroxymethyltransferase.
(19) These results suggest that prevention of xenograft rejection using PAF-antagonist in association with other methods should be further investigated.
(20) The high concentrations of gonadotropins present in immature female rats by the end of the second week of life were suppressed by treatment with an antagonist against luteinizing hormone-releasing hormone (LHRH-A; Org.
Literary
Definition:
(a.) Of or pertaining to letters or literature; pertaining to learning or learned men; as, literary fame; a literary history; literary conversation.
(a.) Versed in, or acquainted with, literature; occupied with literature as a profession; connected with literature or with men of letters; as, a literary man.
Example Sentences:
(1) If wide notice is taken of a current spat over what we can read about Shakespeare’s sexuality into the sonnets in the correspondence columns of the Times Literary Supplement, Sonnet 20 may be a future favourite at civil unions.
(2) Two decades after Donna Tartt soared to literary stardom with her debut The Secret History, the reclusive author is set to release her third novel this autumn.
(3) The cytologic findings can be considered to be satisfactory in regard to literary data.
(4) Wood will play Brinnin, an American poet and literary scenester who was friends with Thomas as well as Truman Capote and Tennessee Williams.
(5) It became his task to use his literary art in an opposite way to Hesse, even though he despaired of what literature might achieve or of the capacity of rich Europeans to change.
(6) But we can add that there is no competition, from the economical viewpoint, between the post-oedipal sublimation, type political involvement, and the preoedipal sublimation, type literary creation.
(7) Literary agent Andrew Kidd said: "I have nothing against readability but some books are more challenging.
(8) He moved on to Tunis and Paris, and became editor-in-chief of the influential literary review Al-Karmel.
(9) Was he being put forward as the foremost literary novelist of his generation, one whose best-known work stands comparison with The Naked and the Dead , Gravity's Rainbow , American Pastoral , Beloved and Underworld ?
(10) She sent the finished manuscript to Elaine Greene , a London literary agent.
(11) She also won four Logies for Most Outstanding Public Affairs Report in 2010, 2011, 2012 and 2013, the Melbourne Press Club Gold Quill in 2013, the George Munster award and the Queensland Premier’s Literary Award – for stories on people smuggling and the culture of rugby league.
(12) Every time he felt the futility of his work for the NAACP, he’d finger the well-worn pages, and it would strengthen his resolve.” This is how classics of this calibre work their way into the literary bloodstream.
(13) Like many ambitious young writers, he sought both popular success and literary acclaim.
(14) His favourite literary genres as a child were detective stories and Greek myths.
(15) But also, in the sense that they crossed over the line of the acceptable literary and visual culture and brought the Mexican modern movement into being.
(16) We arrive also to the conclusion that, in contradiction with what we have seen in the literature overview, it seems that narcissistic personality disorders have no negative effect on literary creation.
(17) The Tasmanian writer said he was “stunned” to be in the running for the prestigious UK-based literary prize, which for the first time has been opened to authors of any nationality.
(18) You may not know it, but literary ghosts are everywhere.
(19) The literary data on the reexamination of the holotype are given.
(20) Despite our difference in generation, gender and literary purpose, it was clear to me that he and I were both working with some of the same aesthetic influences: film, surrealist art and poetry; Freud's avant-garde theories of the unconscious.