(n.) One who contends with another, especially in combat; an adversary; an opponent.
(n.) A muscle which acts in opposition to another; as a flexor, which bends a part, is the antagonist of an extensor, which extends it.
(n.) A medicine which opposes the action of another medicine or of a poison when absorbed into the blood or tissues.
(a.) Antagonistic; opposing; counteracting; as, antagonist schools of philosophy.
Example Sentences:
(1) This death is also dependent on the presence of chloride and is prevented with the non-selective EAA antagonist, kynurenic acid, but is not prevented by QA.
(2) Microionophoretically applied excitatory amino acids induced firing of extracellularly recorded single units in a tissue slice preparation of the mouse cochlear nucleus, and the similarly applied antagonist 2-amino-5-phosphonovalerate (2APV) was demonstrated to be a selective N-methyl-D-aspartate (NMDA) receptor antagonist.
(3) Meanwhile the efficiency of muscarinic antagonists in inhibition of tremor reaction induced by arecoline administration is associated with interaction between the drugs and the M2-subtype.
(4) The anticonvulsant properties of the endogenous excitatory amino acid antagonist, kynurenic acid (KYA), were studied in prepubescent and adult rats using the amygdaloid kindling model of epilepsy.
(5) A novel bicyclic prostaglandin analogue, (1S)-[1 alpha,2 alpha(Z),3 alpha,4 alpha]-7-[3-[(hexylthio)methyl]-7- oxabicyclo [2.2.1]hept-2-yl]-5-heptenoic acid ((-)-10), and its cogeners were found to be potent antagonists at the TxA2 receptor.
(6) This difference was abolished by exposure of the slices to propranolol, a beta-adrenergic receptor antagonist.
(7) The TxA2 antagonistic effects of KW-3635 were compared with that of daltroban in PRP from various animals species.
(8) In experiments performed to determine whether PtdIns(4,5)P2 hydrolysis induced by TRH may have been caused by the elevation of [Ca2+]i, the following results were obtained: the effect of TRH to decrease the level of PtdIns(4,5)P2 was not reproduced by the calcium ionophore A23187 or by membrane depolarization with 50 mM K+; the calcium antagonist TMB-8 did not inhibit the TRH-induced decrease in PtdIns(4,5)P2; and, most importantly, inhibition by EGTA of the elevation of [Ca2+]i did not inhibit the TRH-induced decrease in PtdIns(4,5)P2.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) Selective removal of endothelium had no effect on BK-induced contraction or the action of the antagonists.
(11) The second experiments entailed use of the nonspecific opiate antagonist, naloxone, as well as the specific delta antagonist, ICI 154,129, against seizures induced by icv-administered morphine, morphiceptin, DADL, or DSLET.
(12) These antagonists reverse NMDA-mediated long term influence in these brain areas.
(13) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
(14) Furthermore, the ability of a vasopressin antagonist to lower arterial pressure in NTS hypertensive rats was markedly attenuated by clonidine treatment.
(15) All of the serotonergic antagonists studied had additional effects on the response of the coronary artery to electrical stimulation or to norepinephrine.
(16) Their receptive fields comprise a temporally and spatially linear mechanism (center plus antagonistic surround) that responds to relatively low spatial frequency stimuli, and a temporally nonlinear mechanism, coextensive with the linear mechanism, that--though broad in extent--responds best to high spatial-frequency stimuli.
(17) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(18) Addition in the cultures of 4-deoxypyridoxine, a potent antagonist of vitamin B6 coenzymes, concurrently with the mitogen, inhibits the induction of serine hydroxymethyltransferase.
(19) These results suggest that prevention of xenograft rejection using PAF-antagonist in association with other methods should be further investigated.
(20) The high concentrations of gonadotropins present in immature female rats by the end of the second week of life were suppressed by treatment with an antagonist against luteinizing hormone-releasing hormone (LHRH-A; Org.
Rival
Definition:
(n.) A person having a common right or privilege with another; a partner.
(n.) One who is in pursuit of the same object as another; one striving to reach or obtain something which another is attempting to obtain, and which one only can posses; a competitor; as, rivals in love; rivals for a crown.
(a.) Having the same pretensions or claims; standing in competition for superiority; as, rival lovers; rival claims or pretensions.
(v. t.) To stand in competition with; to strive to gain some object in opposition to; as, to rival one in love.
(v. t.) To strive to equal or exel; to emulate.
(v. i.) To be in rivalry.
Example Sentences:
(1) Nor is this political fantasy: at the European elections in May, across 51 authorities in the north-west and north-east, Ukip finished ahead of Labour in 18 and as its main rival in 30.
(2) I personally felt grateful that British TV set itself apart from its international rivals in this way, not afraid to challenge, to stretch the mind and imagination.
(3) Koons provoked a bigger stir with the news that he would be showing with gallery owner David Zwirner next year in an apparent defection from Zwirner's arch-rival Larry Gagosian, the world's most powerful art dealer.
(4) We believe Oisin has a very exciting future at the BBC.” Clarkson, May and Hammond have signed up to launch a rival show on Amazon’s TV service , while Chris Evans is currently filming a new series of the BBC’s Top Gear show with fellow presenters Matt LeBlanc and Eddie Jordan.
(5) Time suggests that the FBI inquiry has been extended from a relatively narrow look at alleged malpractices by News Corp in America into a more general inquiry into whether the company used possibly illegal strongarm tactics to browbeat rival firms, following allegations of computer hacking made by retail advertising company Floorgraphics.
(6) Pfizer kept up its efforts to get AstraZeneca to the negotiating table over its £63bn approach as it reported revenue well below Wall Street expectations, underscoring its interest in pursuing its UK rival to promote new business growth.
(7) Lion cubs fathered by Cecil, the celebrated lion shot dead in Zimbabwe , may already have been killed by a rival male lion and even if they were still alive there was nothing conservationists could do to protect them, a conservation charity has warned.
(8) Difficult to see how he could become Iraqi PM for a third term with rival sects and blocs strongly against him.
(9) For Argyle the result confirmed their relegation to League One, with the rival fans left to ponder wildly differing prospects next season.
(10) In repeated reconciliation talks overseen by the UN, the ineffectual GNA has so far failed to reach a political compromise with its Tobruk-based rivals in the east, noticeably Haftar, head of the Libyan National Army.
(11) Aware that her press secretary, Bernard Ingham, a former labour correspondent for the Guardian who understood the range of attitudes within trade unions, had tried to soften the impression that she saw Kinnock as another General Galtieri [Argentina’s president during the Falklands war], the draft text tried to distinguish between unions, rival parties and what the final text (the one she actually delivered) called “an organised revolutionary minority” with their “outmoded Marxist dogma about class warfare”.
(12) Rival lender Nationwide reported a fall in house prices of 0.2% in September , the first decrease in 17 months.
(13) The company’s London rivals typically spend half as much.
(14) Considered one of the funniest men in Washington, he injected wit into the debate, telling his rivals that former South Carolina senator Strom Thurmond had four children after age 67.
(15) The temporary ban on dollar clearing means that BNP's clients must engage rival banks to send transactions through the financial system in the US.
(16) It’s a damp squib, a bit of a nothing result,” a leading energy analyst said of a report that is widely expected to endorse provisional findings released in March , and recommend price controls on prepayment meters and setting up a customer database to help rival suppliers target customers stuck on expensive default tariffs.
(17) The Colorado-based tycoon is notoriously secretive and at one point looked as if he was going to mount a rival bid for the US satellite TV company.
(18) The letter contains confidential information that could be used by the carmakers’ rivals, he said.
(19) You get like three days where you have to show up?” But the younger rival managed to turn difficult questions into an opportunity to boast of his humble background and promise of change.
(20) Khan said the garden bridge could rival New York’s high line, a public park built on a 1.45-mile elevated former railway.