(1) This death is also dependent on the presence of chloride and is prevented with the non-selective EAA antagonist, kynurenic acid, but is not prevented by QA.
(2) Microionophoretically applied excitatory amino acids induced firing of extracellularly recorded single units in a tissue slice preparation of the mouse cochlear nucleus, and the similarly applied antagonist 2-amino-5-phosphonovalerate (2APV) was demonstrated to be a selective N-methyl-D-aspartate (NMDA) receptor antagonist.
(3) Meanwhile the efficiency of muscarinic antagonists in inhibition of tremor reaction induced by arecoline administration is associated with interaction between the drugs and the M2-subtype.
(4) The anticonvulsant properties of the endogenous excitatory amino acid antagonist, kynurenic acid (KYA), were studied in prepubescent and adult rats using the amygdaloid kindling model of epilepsy.
(5) A novel bicyclic prostaglandin analogue, (1S)-[1 alpha,2 alpha(Z),3 alpha,4 alpha]-7-[3-[(hexylthio)methyl]-7- oxabicyclo [2.2.1]hept-2-yl]-5-heptenoic acid ((-)-10), and its cogeners were found to be potent antagonists at the TxA2 receptor.
(6) This difference was abolished by exposure of the slices to propranolol, a beta-adrenergic receptor antagonist.
(7) The TxA2 antagonistic effects of KW-3635 were compared with that of daltroban in PRP from various animals species.
(8) In experiments performed to determine whether PtdIns(4,5)P2 hydrolysis induced by TRH may have been caused by the elevation of [Ca2+]i, the following results were obtained: the effect of TRH to decrease the level of PtdIns(4,5)P2 was not reproduced by the calcium ionophore A23187 or by membrane depolarization with 50 mM K+; the calcium antagonist TMB-8 did not inhibit the TRH-induced decrease in PtdIns(4,5)P2; and, most importantly, inhibition by EGTA of the elevation of [Ca2+]i did not inhibit the TRH-induced decrease in PtdIns(4,5)P2.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) Selective removal of endothelium had no effect on BK-induced contraction or the action of the antagonists.
(11) The second experiments entailed use of the nonspecific opiate antagonist, naloxone, as well as the specific delta antagonist, ICI 154,129, against seizures induced by icv-administered morphine, morphiceptin, DADL, or DSLET.
(12) These antagonists reverse NMDA-mediated long term influence in these brain areas.
(13) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
(14) Furthermore, the ability of a vasopressin antagonist to lower arterial pressure in NTS hypertensive rats was markedly attenuated by clonidine treatment.
(15) All of the serotonergic antagonists studied had additional effects on the response of the coronary artery to electrical stimulation or to norepinephrine.
(16) Their receptive fields comprise a temporally and spatially linear mechanism (center plus antagonistic surround) that responds to relatively low spatial frequency stimuli, and a temporally nonlinear mechanism, coextensive with the linear mechanism, that--though broad in extent--responds best to high spatial-frequency stimuli.
(17) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(18) Addition in the cultures of 4-deoxypyridoxine, a potent antagonist of vitamin B6 coenzymes, concurrently with the mitogen, inhibits the induction of serine hydroxymethyltransferase.
(19) These results suggest that prevention of xenograft rejection using PAF-antagonist in association with other methods should be further investigated.
(20) The high concentrations of gonadotropins present in immature female rats by the end of the second week of life were suppressed by treatment with an antagonist against luteinizing hormone-releasing hormone (LHRH-A; Org.
(p. pr.) Waging war; carrying on war.
(p. pr.) Pertaining, or tending, to war; of or relating to belligerents; as, a belligerent tone; belligerent rights.
(n.) A nation or state recognized as carrying on war; a person engaged in warfare.
(1) He could be the target of more punishing wit, as when Michael Foot, noting a tendency to be tougher abroad than at home, called him "a belligerent Bertie Wooster without even a Jeeves to restrain him."
(2) Though the exercises have given the US a chance to vent its frustration at what appears to be state-sponsored espionage and theft on an industrial scale, China has been belligerent.
(3) As well as George Dyer, there was the murderer Perry Smith in the Truman Capote story Infamous, the hot-headed mobster child-killer in Road To Perdition, the brooding Ted Hughes in Gwyneth Paltrow’s Sylvia biopic and a belligerent Mossad assassin in Steven Spielberg’s Munich.
(4) This plays into the widespread belief that Muslims are under attack from a belligerent west and its local proxies.
(5) In international affairs he has found the only posture more dangerous than belligerence – incoherence.
(6) The belligerence of 7 patients who had suffered an acute brain insult was effectively controlled by propranolol in doses of 60 to 320 mg per day.
(7) However, despite the country’s belligerent behaviour in the region and its egregious human rights record, which have long left it isolated, there is an opportunity for engagement given that prominent regime officials have indicated a willingness to reform.
(8) Asked about the status of his own job, the press secretary joked “I’m right here”, telling reporters, in a belligerent line that could have been uttered by his impersonator Melissa McCarthy: “You can keep taking your selfies.” The president was busy sowing confusion by trying a new passive-aggressive tone on Twitter , musing: “While I greatly appreciate the efforts of President Xi & China to help with North Korea, it has not worked out.
(9) Despite the pro-AV leader, Ed Miliband, having stuck his neck out a few times for the yeses, belligerent turns by grumpy old stagers such as John Reid and David Blunkett have created the impression that the people's party has no interest in giving the people more of a say.
(10) To avoid this, women in high executive office often assume a corporate persona that overcompensates by being either brittle and defensive, or Thatcher-esque in terms of belligerence.
(11) European commission upgrades growth forecast for UK economy Read more Michael Hewson, chief market analyst at CMC Markets UK, said: “The initial belligerence of the Trump administration towards China and Japan appears to have given way to a more practicable way of doing things, and while peace may not have broken out quite yet, some welcome pragmatism does appear to be taking hold in Washington.
(12) Mattis pointedly warned North Korea to back off, pledging an “overwhelming” response to any belligerence .
(13) Germany's bureaucratic stasis contrasts with a welter of events, official and unofficial, digital, public and private, in the other former belligerent countries.
(14) For the highest purpose of a democratic government is to bring a society together and hold it together, not to divide it with fears, with rumours of wars, with acts of belligerence against other and then against its own.
(15) But if the odd local blog bristles that us lot should “go back where we came from”, the antipathy to immigrants from farther away ( 8.59% of the local population, according to a recent Oxford University study ; far lower than the 12.5% national average) is much stronger: especially to the eastern Europeans, many of whom have landed in scruffy parts of Cliftonville, where they have belligerently set about opening shops and car washes, and trying to get on with their lives.
(16) Five and a half decades of history show us that such belligerence inhibits better judgement.
(17) The White House condemned the attack as "belligerent", adding: "The United States is firmly committed to the defence of our ally … and to the maintenance of regional peace and stability."
(18) Clapper described the threats from Pyongyang as "very belligerent" and said he is "very concerned about the actions of the new young leader", Kim Jong-un .
(19) Israeli voters – including Labourites disillusioned by what they saw as Palestinian mendacity and belligerency – felt drawn to the old warrior.
(20) These conciliatory tactics did not immediately appeal to Thatcher, though she learned to swallow her belligerence.