(1) This death is also dependent on the presence of chloride and is prevented with the non-selective EAA antagonist, kynurenic acid, but is not prevented by QA.
(2) Microionophoretically applied excitatory amino acids induced firing of extracellularly recorded single units in a tissue slice preparation of the mouse cochlear nucleus, and the similarly applied antagonist 2-amino-5-phosphonovalerate (2APV) was demonstrated to be a selective N-methyl-D-aspartate (NMDA) receptor antagonist.
(3) Meanwhile the efficiency of muscarinic antagonists in inhibition of tremor reaction induced by arecoline administration is associated with interaction between the drugs and the M2-subtype.
(4) The anticonvulsant properties of the endogenous excitatory amino acid antagonist, kynurenic acid (KYA), were studied in prepubescent and adult rats using the amygdaloid kindling model of epilepsy.
(5) A novel bicyclic prostaglandin analogue, (1S)-[1 alpha,2 alpha(Z),3 alpha,4 alpha]-7-[3-[(hexylthio)methyl]-7- oxabicyclo [2.2.1]hept-2-yl]-5-heptenoic acid ((-)-10), and its cogeners were found to be potent antagonists at the TxA2 receptor.
(6) This difference was abolished by exposure of the slices to propranolol, a beta-adrenergic receptor antagonist.
(7) The TxA2 antagonistic effects of KW-3635 were compared with that of daltroban in PRP from various animals species.
(8) In experiments performed to determine whether PtdIns(4,5)P2 hydrolysis induced by TRH may have been caused by the elevation of [Ca2+]i, the following results were obtained: the effect of TRH to decrease the level of PtdIns(4,5)P2 was not reproduced by the calcium ionophore A23187 or by membrane depolarization with 50 mM K+; the calcium antagonist TMB-8 did not inhibit the TRH-induced decrease in PtdIns(4,5)P2; and, most importantly, inhibition by EGTA of the elevation of [Ca2+]i did not inhibit the TRH-induced decrease in PtdIns(4,5)P2.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) Selective removal of endothelium had no effect on BK-induced contraction or the action of the antagonists.
(11) The second experiments entailed use of the nonspecific opiate antagonist, naloxone, as well as the specific delta antagonist, ICI 154,129, against seizures induced by icv-administered morphine, morphiceptin, DADL, or DSLET.
(12) These antagonists reverse NMDA-mediated long term influence in these brain areas.
(13) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
(14) Furthermore, the ability of a vasopressin antagonist to lower arterial pressure in NTS hypertensive rats was markedly attenuated by clonidine treatment.
(15) All of the serotonergic antagonists studied had additional effects on the response of the coronary artery to electrical stimulation or to norepinephrine.
(16) Their receptive fields comprise a temporally and spatially linear mechanism (center plus antagonistic surround) that responds to relatively low spatial frequency stimuli, and a temporally nonlinear mechanism, coextensive with the linear mechanism, that--though broad in extent--responds best to high spatial-frequency stimuli.
(17) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(18) Addition in the cultures of 4-deoxypyridoxine, a potent antagonist of vitamin B6 coenzymes, concurrently with the mitogen, inhibits the induction of serine hydroxymethyltransferase.
(19) These results suggest that prevention of xenograft rejection using PAF-antagonist in association with other methods should be further investigated.
(20) The high concentrations of gonadotropins present in immature female rats by the end of the second week of life were suppressed by treatment with an antagonist against luteinizing hormone-releasing hormone (LHRH-A; Org.
Disconnect
Definition:
(v. t.) To dissolve the union or connection of; to disunite; to sever; to separate; to disperse.
Example Sentences:
(1) Then the esophagogastric variceal network was thrombosed by means of a catheter introduced during laparotomy, which created a portoazygos disconnection.
(2) It helped pay the bills and caused me to ponder on the disconnection between theory and reality.
(3) A pre-operative diagnosis of otosclerosis was made but at tympanotomy, the stapes crura in each ear was found to be disconnected from the footplate, the ossicular chain being otherwise normal.
(4) Two years later, the Guardian could point to reforms that owed much to what Ashley called his "bloody-mindedness" in five areas: non-disclosure of victims' names in rape cases; the rights of battered wives; the ending of fuel disconnections for elderly people; a royal commission on the legal profession; and civil liability for damages such as those due to thalidomide victims.
(5) In an emergency, the devices use multiple mechanisms – including clamps and shears – to try to choke off the oil flowing up from a pipe and disconnect the rig from the well.
(6) Nearly three quarters (73%) said if they were disconnected, they would find their ability to use vital commercial services, such as shopping and banking, completely disrupted or fairly harmed.
(7) Keep asking questions like that and you’re going to get hung up on, like right now,” he said, then disconnected the line.
(8) Frontal hypothalamic deafferentation (FHD), which disconnects the anterior hypothalamus from the preoptic area, stops the twice daily surges of prolactin secretion of pregnancy or pseudopregnancy in the rat, and causes rapid luteolysis.
(9) The results of these studies support the contention that anterolateral MBH neural connections may constitute a dynamic neural substrate contributing to a gradual improvement in neuroendocrine function observed after early surgical disconnections.
(10) O2 has warned that it will disconnect anyone it discovers doing that, though it would not say how it would identify them.
(11) For me, the simple reason is I tried a three-day week and found I struggled to keep on top of work, felt disconnected from my colleagues' rhythm, felt guilty about so much time off, and was so bad at freelancing I ended up working many more hours for less money.
(12) The stages of recognition are analysed through this case of visual verbal disconnection and the importance of memory in perception is highlighted.
(13) Similarities were increased number of lipid droplets in the cumulus cells, widened peri-vitelline space, peripheral displacement or breakdown of the oocyte nucleus and disconnection of the junctions between cumulus cell projections and the oolemma.
(14) Attempts to estimate mean skin temperature for subjects during prolonged experiments in field conditions are often made difficult because probes become disconnected or cease to function.
(15) Where are Cisco and other companies whose equipment is used to connect the net and by some governments to disconnect it?
(16) The emergency operation which has effectively achieved the stopping of the esophageal bleeding has been the porto-azygos disconnection, which allows later a portosystemic shunt with a greater probability of success.
(17) Surgery, performed under cardio-pulmonary bypass after epicardial mapping, consisted in atrioventricular disconnection using no special physical agent.
(18) Hypoemotionality was found only for visual stimuli, since auditory and tactile modalities were totally spared, suggesting a visual-limbic disconnection mechanism.
(19) In the first case the exhaust system intentionally had been disconnected.
(20) Forced removals and dumping of millions of people into small, disconnected, barren, poor reserve areas, bereft of adequate medical, psychiatric and public health services (the 'final solution' of the 'native problem') causes widespread malnutrition, infectious and other diseases, and high mortality and mental-illness rates.