(a.) Of or pertaining to the last syllable but two.
(n.) The antepenult.
Example Sentences:
(1) After glucoamylase digestion, maltopentaosides with a 3,6-anhydro glucose as antepenultimate unit were produced in good yield.
(2) The enzyme failed to hydrolyze peptides having a proline or cysteic acid in the COOH-terminal, penultimate, and antepenultimate positions.
(3) Kenny continues his campaign with the men's match sprint quarter-finals while Victoria Pendleton begins the antepenultimate day of her track-racing career with qualifying and preliminary rounds in the sprint.
(4) In that case the antepenultimate residue (D, V, I or T) would be only weakly stringent, and some sequences primed by H instead of K would be recognized in animal as well as in yeast cells.
(5) Among the Mohawk children, the earliest segmentation of words was phonological rather than morphological: stressed syllables, usually penultimate or antepenultimate, were extracted first.
(6) A survey of carboxypeptidase Y-catalyzed carboxyl-terminal modification of short peptides in the presence of various amino acids revealed that transpeptidation occurred in significant yield only with peptides containing a proline at the penultimate or antepenultimate position.
(7) We have also observed that guanosine at the antepenultimate position provides a second consensus feature among IVSs in tRNA precursors.
(8) Comparison with hog peptides known to contain all the triiodothyronine (T3) of the mature Tg suggests that the antepenultimate amino acid, a tyrosine residue could be involved in hormone formation.
(9) Cell retention signals of the type HXEL-COOH appear to be common in higher eukaryotes and tolerate considerable variation at the antepenultimate X residue.
(10) These substrates correspond to the carboxyl-terminal three amino acids of the mature forms of epidermal growth factor (EGF) and beta-nerve growth factor (beta-NGF), as well as various substitutions in the penultimate and antepenultimate positions, and, as such, represent potential recognition sites for precursor processing.
(11) The effect of varying the antepenultimate amino acid residue in this series on the biological activity was studied.
(12) Families of peptides of the structure S-Y-S-G-G-L-L-L were generated by successively replacing the N-terminal serine, the penultimate tyrosine, and the antepenultimate serine with all 19 commonly occurring amino acids, which were then assessed for their reactivity with the rat liver enzyme.
Penultimate
Definition:
(a.) Last but one; as, the penultimate syllable, the last syllable but one of a word.
(n.) The penult.
Example Sentences:
(1) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(2) In tripeptides with a neutral amino acid in the penultimate position, amidation, took place readily but the reaction was slower when this position was occupied by an acidic or a basic residue.
(3) 7.21pm GMT The normal hill world champion, Anders Bardal of Norway, is the penultimate man off the normal hill.
(4) A metabolite of nabilone in feces has been identified as a diol formed by reduction of the 9-keto group plus oxidation at the penultimate carbon of the dimethylheptyl side chain.
(5) Thus, a greater than 1300-fold range in apparent inhibitor constants was observed by substitution at the -1 (penultimate) position in a C-terminal glycine-containing tripeptide with each of the 20 common L-amino acids.
(6) "I'm Ms Dy-na-mi-TEE-ee," she sang on the chorus, putting an emphasis on the penultimate syllable.
(7) In this study, to achieve a systematic analysis of the specificity of MAP action, each of the 20 amino acids was introduced at the penultimate position of methionyl-tRNA synthetase of E. coli and the extent of in vivo methionine excision was measured.
(8) The birth interval between the index and penultimate child was 2 years or less in 20% and 2-3 years in 40%.
(9) The fast-twitch Ca2+ ATPase transcript undergoes developmentally regulated alternative splicing in which a penultimate 42-base pair exon is retained in the adult transcript but is excised in the neonatal transcript.
(10) 60% that of the yeast iso-1-cytochrome c. N-terminal processing of indigenous rat cytochrome c, in which the N-terminal methionine residue is cleaved and the penultimate glycine residue is acetylated, also occurred in yeast.
(11) These data indicate that the penultimate amino acid for the primary cleavage site of factor X by CP is proline-20 and for the secondary sites, proline-13 and proline-28.
(12) Placing a ribonucleotide at the penultimate position coupled by a phosphorothioate linkage to a terminal 2',3'-dideoxynucleotide reduced the rate of exonucleolytic activity almost 30,000-fold (half-life approximately 16 h).
(13) Oxidation of dihydrostreptomycin 6-phosphate to streptomycin 6-phosphate very probably represents the penultimate step in the biosynthesis of streptomycin.
(14) Charlotte Eagles gave Chivas USA an almighty scare, by equalizing in the penultimate minute of regulation time, through Mauricio Salles, only for Jose Correa to break their hearts deep into stoppage time.
(15) Subsequent removal of penultimate galactose residues returned both antibody survival time in the circulation and organ distribution to near normal.
(16) This hypothesis predicts that tumor cells of the ultimate stage will carry each of the events; cells of the penultimate stage will carry each of the events minus the last one; and so on.
(17) The data imply that sensitivity to the 2',5'-phosphodiesterase activity of mouse L cells requires the presence of 3'-hydroxyl moiety in the penultimate nucleotide.
(18) It could have been his team celebrating a Double had they won at Villa Park and avoided defeat in their penultimate league game of the season to Leeds United, a match in which events seemed to conspire against them as dramatically as they went in favour of Ferguson’s side.
(19) Instead it is an exopeptidase with a high specificity for NH2-terminal-free peptides containing a proline residue in the penultimate position and releases the dipeptide with proline being the COOH-terminal moiety.
(20) On the other hand, the maximum OERs for two GSH- mutants, 7 and 821, both deficient in gamma-glutamylcysteine synthetase, the penultimate enzyme in the GSH biosynthetic pathway, were about 2.7 and the K-values were about 0.06% O2 for both.