(n.) A hydrocarbon, C6H4.C2O2.C6H4, subliming in shining yellow needles. It is obtained by oxidation of anthracene.
Example Sentences:
(1) We have studied the effects of clinically useful anthraquinones on the cardiac sarcoplasmic reticulum calcium-release channel.
(2) Since the mutagenic compounds isolated are anthraquinone derivatives with the exception of compound 1, structure-mutagenicity relationships of the anthraquinones were also studied.
(3) We have conducted stopped-flow kinetics association and dissociation experiments on the interaction of these anthraquinones with calf thymus DNA and with DNA polymers with alternating AT and GC base pairs to experimentally determine the binding mode and how the threading mode affects intercalation rates relative to similarly substituted classical intercalators.
(4) The results were compared with that of versicolorin A, an anthraquinone with bisfuran ring, which had been proved to be genotoxic on this assay.
(5) From lettuce and string beans quercetin was isolated (after chemical hydrolysis) and in rhubarb emodin, an anthraquinon, was detected.
(6) Mitoxantrone is an anthraquinone antineoplastic agent with structural similarities to doxorubicin.
(7) A few were positive for phlobatannins and anthraquinones.
(8) The maximum content of antraquinones on a fresh weight basis was 0.334 percent, which is higher than the content of total anthraquinones in the dry seeds.
(9) 1,4-Diamino-substituted anthraquinone antitumor agents (mitoxantrone and ametantrone) and structurally related 1,5- and 1,8-diamino-substituted compounds (AM1 and AM2) were tested for their ability to photosensitize human leukemic cells in culture.
(10) Doxorubicin enhances the binding of [3H]ryanodine to SR membranes and soluble receptor preparations and induces Ca2+ release from SR vesicles in a highly Ca2(+)-dependent manner, suggesting that anthraquinones promote the open state of the junctional Ca2+ release channel by increasing the affinity of the Ca2+ activator site for Ca2+.
(11) The carbonate- and alkali-soluble pigments have been further separated by chromatography and shown to consist of anthraquinone derivatives.
(12) The anthraquinones danthron, doxorubicin and emodin were poorly metabolized in this system.
(13) Ca(2+)-calmodulin-dependent myosin light chain kinase (MLCK) is inhibited by a range of di-, tri- and tetrahydroxylated anthraquinones (IC50 values 2 to 53 microM), the most potent inhibitors being the more polar compounds, namely mitoxantrone (IC50 2 microM) and emodin (1,3,8-trihydroxy-6-methylanthraquinone) (IC50 8 microM).
(14) These results agree with recent observations on the effects of senna in rats and mice, and do not support earlier claims that myenteric neurons are killed by anthraquinone purgatives.
(15) Sodium 2-hydroxy-anthraquinone sulphate and anthraquinone-2-suphonate were also active as antifeedants for the species tested.
(16) Three compounds, [[2-[[2-(anthraquinon-1- ylamino)ethyl]amino]ethyl]amine-N,N']dichloroplatinum(II), [[2-[[3-(anthraquinon-1-ylamino)propyl]amino]ethyl]amine- N,N']dichloroplatinum(II), and [[2-[[3-anthraquinon-1- yloxy)propyl]amino]ethyl]amine-N,N']dichloroplatinum(II), were as active in vitro as cisplatin (ED50 = 2-4 x 10(-7) M) while on a molar basis their acute in vivo toxicity was significantly lower than that of cisplatin.
(17) Components S 383-O and S 383-A were identified as known derivatives of anthraquinone and naphthacenequinone, respectively, previously isolated from cultures of other blocked mutants of S. galilaeus strains.
(18) The naturally-occurring anthraquinones (AQs), alizarin (1,2-dihydroxyanthraquinone) and lucidin (1,3-dihydroxy-2-hydroxymethylanthraquinone), were incubated with DNA in the presence of S9 mix.
(19) The anthraquinone was shown to enhance binding to a complementary RNA when linked to the 3' and 5' end.
(20) The in vitro microbial degradation and the urinary excretion and biliary secretion in rats of two anthraquinone glycosides (sennosides A and B) and four aglycones (sennidins A and B, rhein, and danthron) were studied using a high performance liquid chromatographic system with gradient elution and amperometric detection.
Natural
Definition:
(a.) Fixed or determined by nature; pertaining to the constitution of a thing; belonging to native character; according to nature; essential; characteristic; not artifical, foreign, assumed, put on, or acquired; as, the natural growth of animals or plants; the natural motion of a gravitating body; natural strength or disposition; the natural heat of the body; natural color.
(a.) Conformed to the order, laws, or actual facts, of nature; consonant to the methods of nature; according to the stated course of things, or in accordance with the laws which govern events, feelings, etc.; not exceptional or violent; legitimate; normal; regular; as, the natural consequence of crime; a natural death.
(a.) Having to do with existing system to things; dealing with, or derived from, the creation, or the world of matter and mind, as known by man; within the scope of human reason or experience; not supernatural; as, a natural law; natural science; history, theology.
(a.) Conformed to truth or reality
(a.) Springing from true sentiment; not artifical or exaggerated; -- said of action, delivery, etc.; as, a natural gesture, tone, etc.
(a.) Resembling the object imitated; true to nature; according to the life; -- said of anything copied or imitated; as, a portrait is natural.
(a.) Having the character or sentiments properly belonging to one's position; not unnatural in feelings.
(a.) Connected by the ties of consanguinity.
(a.) Begotten without the sanction of law; born out of wedlock; illegitimate; bastard; as, a natural child.
(a.) Of or pertaining to the lower or animal nature, as contrasted with the higher or moral powers, or that which is spiritual; being in a state of nature; unregenerate.
(a.) Belonging to, to be taken in, or referred to, some system, in which the base is 1; -- said or certain functions or numbers; as, natural numbers, those commencing at 1; natural sines, cosines, etc., those taken in arcs whose radii are 1.
(a.) Produced by natural organs, as those of the human throat, in distinction from instrumental music.
(a.) Of or pertaining to a key which has neither a flat nor a sharp for its signature, as the key of C major.
(a.) Applied to an air or modulation of harmony which moves by easy and smooth transitions, digressing but little from the original key.
(n.) A native; an aboriginal.
(n.) Natural gifts, impulses, etc.
(n.) One born without the usual powers of reason or understanding; an idiot.
(n.) A character [/] used to contradict, or to remove the effect of, a sharp or flat which has preceded it, and to restore the unaltered note.
Example Sentences:
(1) The results indicated that neuropsychological measures may serve to broaden the concept of intelligence and that a brain-related criterion may contribute to a fuller understanding of its nature.
(2) In Patient 2 they were at first paroxysmal and unformed, with more prolonged metamorphopsia; later there appeared to be palinoptic formed images, possibly postictal in nature.
(3) We conclude that the priming effect is not a clinically significant phenomenon during natural pollen exposure in allergic rhinitis patients.
(4) Quantitative determinations indicate that the amount of PBG-D mRNA is modulated both by the erythroid nature of the tissue and by cell proliferation, probably at the transcriptional level.
(5) The severity and site of hypertrophy is important in determining the clinical picture and the natural history of hypertrophic cardiomyopathy (HCM).
(6) Here, we review the nature of the heart sound signal and the various signal-processing techniques that have been applied to PCG analysis.
(7) To investigate the immunomodulating properties of cis-diamminedichloroplatinum (II) (CDDP), we studied the drug's effects on natural killer (NK) lymphocyte cytotoxicity.
(8) Examined specific relationships, as they occur in nature, between particular dietary variables or groups of variables and specific MMPI subscales.
(9) Natural tubulin polymerization leads to the formation of hooks on microtubular structures.
(10) Trichostatin C is presumably the first example of a glucopyranosyl hydroxamate from nature.
(11) The present study was undertaken to find out the nature of enzymes responsible for the processing of DV antigen in M phi.
(12) The cyclical nature of pyromania has parallels in cycles of reform in standards of civil commitment (Livermore, Malmquist & Meehl, 1958; Dershowitz, 1974), in the use of physical therapies and medications (Tourney, 1967; Mora, 1974), in treatment of the chronically mentally ill (Deutsch, 1949; Morrissey & Goldman, 1984), and in institutional practices (Treffert, 1967; Morrissey, Goldman & Klerman (1980).
(13) The nature of the putative autoantigen in Graves' ophthalmopathy (Go) remains an enigma but the sequence similarity between thyroglobulin (Tg) and acetylcholinesterase (ACHE) provides a rationale for epitopes which are common to the thyroid gland and the eye orbit.
(14) Further exploration of these excretory pathways will provide interesting new insights on the numerous cholestatic and hyperbilirubinemic syndromes that occur in nature.
(15) In this way they offer the doctor the chance of preventing genetic handicaps that cannot be obtained by natural reproduction, and that therefore should be used.
(16) The nature, intracellular distribution, and role of proteins synthesized during meiotic maturation of mouse oocytes in vitro have been examined.
(17) Natural killer cells (CD8+CD57+) as well as activated T cells (CD3+HLA-DR+) were significantly increased in patients with sarcoidosis.
(18) In certain cases, the effects of these substances are enhanced, in others, they are inhibited by compounds that were isolated from natural sources or prepared by chemical synthesis.
(19) Analysis of 156 records relating to patients at the age of 15 to 85 years with extended purulent peritonitis of the surgical and gynecological genesis (the toxic phase, VI category ASA) showed that combination of programmed sanitation laparotomy and intensive antibacterial therapy performed as short-term courses before, during and after the operation with an account of the information on the nature of the microbial associations and antibioticograms was an efficient procedure in treatment of severe peritonitis.
(20) There is no convincing evidence that immunosuppression is effective, also because the natural history of the disease is characterised by a spontaneous disappearance of the factor VIII-C inhibitor.