What's the difference between antidotal and mithridatic?
Antidotal
Definition:
(a.) Having the quality an antidote; fitted to counteract the effects of poison.
Example Sentences:
(1) This may result in the unnecessary implementation of antidotal therapy.
(2) These results are in marked contrast to our results with stroma-free methemoglobin solutions (SFMS) which showed SFMS to be a highly effective antidote against four times the LD90 when administered 30 seconds after an intravenous injection of cyanide.
(3) Three esterase inhibitors, phenylmethylsulfonyl fluoride, bis-(p-nitrophenyl)-phosphate, and diisopropylfluorophosphate, had no effect on the antidote effectiveness of N-acetylcysteine, although each provided partial protection against acetaminophen poisoning.
(4) Sixteen chelating agents were examined to determine their relative efficacy as antidotes in acute uranyl acetate intoxication in mice after subcutaneous administration.
(5) The terrorists know that if Iraq and Afghanistan survive their assault, come through their travails, seize the opportunity the future offers, then those countries will stand not just as nations liberated from oppression, but as a lesson to humankind everywhere and a profound antidote to the poison of religious extremism.
(6) The implication of the cholinergic system in such intoxications prompted us to study the effect of different combinations of antidotes on the acetylcholine (ACh) synthesizing system in mouse brain in vivo.
(7) Although differences between plasma cyanide levels in the two groups only attained significance 1 h after administering the antidote (0.8 vs. 2.74 mumol .
(8) Since there is no specific antidot against these drugs, therapy of side effects is limited to symptomatic treatment including administration of cholinergic drugs.
(9) Lavage also provides an excellent route for activated charcoal and selected antidotes.
(10) Studies attempting to measure cyanide in the blood of methyl isocyanate-exposed rats, and attempting to affect lethality with a cyanide antidote (sodium nitrite and sodium thiosulfate) gave negative results.
(11) 2-Mercaptosuccinic and ascorbic acids were not effective as antidotes for parenteral vanadium intoxication.
(12) Oxygen, thiosulfate and hydroxycobalamin are probably the best and safest currently available antidotes to manage this difficult setting.
(13) He has been declared "a Shakespearean fool, the only one who can say what others can't" and "an antidote to the proliferation of neo-Nazi movements which took hold of Hungary and Greece".
(14) The best antidotal effect was demonstrated for the combination of atropine and methoxime (tested as therapeutic index or D50 index).
(15) By measuring the methemoglobin formation, the permeabilities of some cyanide antidotes passing through mouse erythrocyte membrane were studied.
(16) This was the first recorded case in which antidotal methemoglobin production was attempted.
(17) Therefore, STS was confirmed to be a powerful antidote against cis-platinum in plasma.
(18) Clinacanthus nutans Burm, a herb reputed in Thailand and Malaysia to be "snakebite antidote" has been tested in vitro and in vivo for antivenin activity.
(19) Recent literature suggests using initial charcoal therapy instead of ipecac as a first-line antidotal agent for many acute poisonings.
(20) A comparison of these results with the predicted relative abilities of the enantiomers to participate in each of the three antidotal mechanisms leads to the conclusion that, under these experimental conditions, the best correlation exists with the cyanide detoxification mechanism.
Mithridatic
Definition:
(a.) Of or pertaining to King Mithridates, or to a mithridate.