(n.) A remedy to counteract the effects of poison, or of anything noxious taken into the stomach; -- used with against, for, or to; as, an antidote against, for, or to, poison.
(n.) Whatever tends to prevent mischievous effects, or to counteract evil which something else might produce.
(v. t.) To counteract or prevent the effects of, by giving or taking an antidote.
(v. t.) To fortify or preserve by an antidote.
Example Sentences:
(1) This may result in the unnecessary implementation of antidotal therapy.
(2) These results are in marked contrast to our results with stroma-free methemoglobin solutions (SFMS) which showed SFMS to be a highly effective antidote against four times the LD90 when administered 30 seconds after an intravenous injection of cyanide.
(3) Three esterase inhibitors, phenylmethylsulfonyl fluoride, bis-(p-nitrophenyl)-phosphate, and diisopropylfluorophosphate, had no effect on the antidote effectiveness of N-acetylcysteine, although each provided partial protection against acetaminophen poisoning.
(4) Sixteen chelating agents were examined to determine their relative efficacy as antidotes in acute uranyl acetate intoxication in mice after subcutaneous administration.
(5) The terrorists know that if Iraq and Afghanistan survive their assault, come through their travails, seize the opportunity the future offers, then those countries will stand not just as nations liberated from oppression, but as a lesson to humankind everywhere and a profound antidote to the poison of religious extremism.
(6) The implication of the cholinergic system in such intoxications prompted us to study the effect of different combinations of antidotes on the acetylcholine (ACh) synthesizing system in mouse brain in vivo.
(7) Although differences between plasma cyanide levels in the two groups only attained significance 1 h after administering the antidote (0.8 vs. 2.74 mumol .
(8) Since there is no specific antidot against these drugs, therapy of side effects is limited to symptomatic treatment including administration of cholinergic drugs.
(9) Lavage also provides an excellent route for activated charcoal and selected antidotes.
(10) Studies attempting to measure cyanide in the blood of methyl isocyanate-exposed rats, and attempting to affect lethality with a cyanide antidote (sodium nitrite and sodium thiosulfate) gave negative results.
(11) 2-Mercaptosuccinic and ascorbic acids were not effective as antidotes for parenteral vanadium intoxication.
(12) Oxygen, thiosulfate and hydroxycobalamin are probably the best and safest currently available antidotes to manage this difficult setting.
(13) He has been declared "a Shakespearean fool, the only one who can say what others can't" and "an antidote to the proliferation of neo-Nazi movements which took hold of Hungary and Greece".
(14) The best antidotal effect was demonstrated for the combination of atropine and methoxime (tested as therapeutic index or D50 index).
(15) By measuring the methemoglobin formation, the permeabilities of some cyanide antidotes passing through mouse erythrocyte membrane were studied.
(16) This was the first recorded case in which antidotal methemoglobin production was attempted.
(17) Therefore, STS was confirmed to be a powerful antidote against cis-platinum in plasma.
(18) Clinacanthus nutans Burm, a herb reputed in Thailand and Malaysia to be "snakebite antidote" has been tested in vitro and in vivo for antivenin activity.
(19) Recent literature suggests using initial charcoal therapy instead of ipecac as a first-line antidotal agent for many acute poisonings.
(20) A comparison of these results with the predicted relative abilities of the enantiomers to participate in each of the three antidotal mechanisms leads to the conclusion that, under these experimental conditions, the best correlation exists with the cyanide detoxification mechanism.
Counteract
Definition:
(v. t.) To act in opposition to; to hinder, defeat, or frustrate, by contrary agency or influence; as, to counteract the effect of medicines; to counteract good advice.
Example Sentences:
(1) The origins of aging of higher forms of life, particularly humans, is presented as the consequence of an evolved balance between 4 specific kinds of dysfunction-producing events and 4 kinds of evolved counteracting effects in long-lived forms.
(2) Conversely, rat galanin increased unstimulated glucagon output (approximately 20%, P less than 0.05), potentiated the glucagon response to arginine (approximately 50%, P less than 0.05) and VIP (approximately 90%, P less than 0.05), and counteracted the suppressor effect of glucose on alpha-cell secretion.
(3) This inhibition is counteracted by the somewhat slower increase of NE turnover resulting in normalization of LH levels.
(4) These results suggest that CPZ interacts with smg p21B, smg GDS, or both, and thereby inhibits the smg GDS action, and that CPZ also interacts with the acidic phospholipids and thereby counteracts their inhibitory effect on the smg GDS action.
(5) Extracts from arrested cells counteracted the stimulating effects of extracts from proliferating cells with kinetics suggesting competitive interaction between stimulating and inhibitory factors.
(6) Acetylcholine increases their turnover, Atropine reduces it, and the addition of atropine counteracts the effect of acetylcholine in all these phospholipids.
(7) Whether they affect ureteral motility in vivo or whether they can counteract ureteral spasm associated with ureteral stones have not been established.
(8) Metoclopramide did not counteract the apomorphine effect and, in higher doses, water intake was even further reduced.
(9) This effect increases with the estrogen dose and is counteracted more effectively by androgenic progestogens such as levonorgestrel than by nonandrogenic progestogens such as desogestrel.
(10) PGE2 counteracted the NA-effect in the former group of patients but did not affect the influence of NA at term.
(11) Addition of heme in vitro (10(-6)M) to the latter nuclei results in a significant counteraction of the decreased cytochrome P-450 (c + d) mRNA transcription.
(12) Two functions of these have been proposed: 1) that they are compatible osmolytes which regulate cell volume (against high external NaCl) without inhibiting proteins and 2) that methylamines (GPC and betaine) are counteracting osmolytes which stabilize proteins against perturbation from high renal urea.
(13) For this rather large pressures (about 700 hPa) are required to overcome the surface forces counteracting droplet formation.
(14) The drop in the blood-sugar levels was counteracted by corresponding infusions of glucose by the BIOSTATOR via a special clamp technique.
(15) In the wild strain (Em 5297a) thiourea is tenfold more toxic on an allantoin medium than on an inorganic nitrogen medium; allantoin as well as urea counteract thiourea toxicity in the allantoin nitrogen medium.
(16) Retinal traction can be counteracted by the oil up to a calculated threshold value, depending on the size and shape of the tear, the strength of the surface tension and, most importantly, the distance between the retina and choroid.
(17) Some of the changes found may be a result of adaptive mechanisms occurring in order to counteract the different biophysical effects of ethanol.
(18) This study evaluates whether suturing of replaced flaps with crown-attached sutures, following reconstructive surgery, counteracts postoperative recession of the gingival margins and facilitates new attachment.
(19) In the present article is shown that the histamine releasing effect is counteracted by the addition of histamine to the superfusion fluid.
(20) This barrier effect was partially counteracted by monensin or carbonyl cyanide m-chlorophenylhydrazone.