(n.) A compound of antimonious acid and a base or basic radical.
(n.) Stibnite.
Example Sentences:
(1) Extrapolation of the amount of FSBA required to inactivate the protein indicated that 1 mol of FSBA was sufficient to inhibit the activity of 1 mol of ArsA protein in the absence of substrates, while only 0.5 mol was required in the presence of the anionic substrate antimonite.
(2) The estimated Ki values for FSBA were 0.4 mM in the absence of antimonite and 0.1 mM in the presence of antimonite, suggesting that the binding of antimonite increased the affinity of ArsA protein for FSBA.
(3) ATP was partially protected from trypsin digestion, while the anionic substrate antimonite alone had no effect on proteolysis.
(4) Partial deletion of 56 bp from the 3' end of the arsC gene resulted in loss of resistance to arsenate; the determinant retained arsenite and antimonite resistances.
(5) The plasmid-borne arsenical resistance operon encodes an ATP-driven oxyanion pump for the extrusion of the oxyanions arsenite, antimonite and arsenate from bacterial cells.
(6) In the presence of antimonite the weight average molecular mass increased to a mass in excess of 100 kDa.
(7) The ars operon was induced by arsenate [As(V)], arsenite [As(III)], and antimonite [Sb(III)], to which the strains were resistant, plus Bi(III) in S. aureus.
(8) The arsenate, arsenite, and antimonite resistance was shown to be inducible by all three heavy metal ions.
(9) These results demonstrate that ATP and antimonite together produce a conformational change which is different from that of the ArsA protein in the presence of either substrate alone and suggest interaction between the oxyanion and ATP binding sites.
(10) When expressed in Escherichia coli this ATP-driven oxyanion pump catalyzes extrusion of the oxyanions arsenite, antimonite and arsenate.
(11) The arsenate, arsenite, and antimonite resistance region of the Staphylococcus xylosus plasmid pSX267 was subcloned in Staphylococcus carnosus.
(12) Membranes of uncA mutants containing both the ArsA and ArsB proteins exhibit arsenite(antimonite)-stimulated ATPase activity.
(13) The catalytic component of the pump, the 63 kDa ArsA protein, hydrolyses ATP in the presence of its anionic substrate antimonite (SbO2-).
(14) The cloned staphylococcal ars operon confers resistances to arsenate, arsenite, and antimonite in S. aureus and Bacillus subtilis.
(15) The inactivation of arsR also resulted in reduction of resistance to arsenite and antimonite, while arsenate resistance was unaffected.
(16) Purified ArsA protein is an arsenite(antimonite)-stimulated ATPase.
(17) ATP and antimonite together provided complete protection, indicating interaction of the anion- and nucleotide-binding sites.
(18) The same operon was also expressed in E. coli and conferred resistance to arsenite but less resistance to arsenate and antimonite.
(19) In most cases these provide resistance to both the oxyanions of +III oxidation state, antimonite and arsenite, and the +V oxidation state, arsenate.
(20) The ArsA protein, the catalytic component of the plasmid-encoded resistance system for removal of the toxic oxyanions arsenite, antimonite, and arsenate from bacterial cells, catalyzes oxyanion-stimulated ATP hydrolysis.
Antimony
Definition:
(n.) An elementary substance, resembling a metal in its appearance and physical properties, but in its chemical relations belonging to the class of nonmetallic substances. Atomic weight, 120. Symbol, Sb.
Example Sentences:
(1) By means of rapid planar Hill type antimony-bismuth thermophiles the initial heat liberated by papillary muscles was measured synchronously with developed tension for control (C), pressure-overload (GOP), and hypothyrotic (PTU) rat myocardium (chronic experiments) and after application of 10(-6) M isoproterenol or 200 10(-6) M UDCG-115.
(2) This area was selected for study because of its large mineral deposits and concentration of elements, e.g., iron, copper, silver, antimony, and particularly mercury.
(3) The inhibition of osmotic stimulated water flow in the isolated toad bladder by 0.1 mM sodium stibogluconate (pentavalent antimony) is described.
(4) The antimony in metallic kitchen ware was determined.
(5) Although previously published animal data suggest utility of Tc-99m stannous phytate for lymph-node imaging, Tc-99m antimony sulfide was shown in this clinical comparison to provide a more reliable representation of lymph-node anatomy.
(6) Rather surprising were the contents of mercury, indium, and cadmium found in some of the alloys as well as the low-level concentration of lead, and in a few cases antimony.
(7) Organic antimonials were most active when anmastigotes were exposed to them prior to entry of the parasites into host cells.
(8) Ureastibamine, a pentavalent antimonial, reduced the parasitic load in the 60-day model of infection of L. donovani in hamsters.
(9) As dosage regimens for treating leishmaniasis have evolved, the daily dose of antimony and the duration of therapy have been progressively increased to combat unresponsiveness to therapy.
(10) To obtain the usual values of arsenic, beryllium, bismuth, cadmium, chromium, cobalt, copper, mercury, methyl mercury, manganese, molybdenum, nickel, lead, antimony, vanadium, and zinc in the normal human body, the amounts of 15 metals were determined in 15 male and 15 female Japanese cadavers (average weight, 55 kg [121 lb]).
(11) It is an effective alternative to antimony therapy, and in some cases resistant to antimony, it may be the drug of choice.
(12) Solid state memories are preferred, glass or antimony electrodes may be used and the data analysis should be performed on an ordinary personal computer.
(13) There is only a few hundred ohms resistance between an antimony pH electrode and the reference electrode so that the voltage generated can be recorded with simple low-impedance recorders linked to microcomputers.
(14) A series of 31 patients presenting with skin lesions with positive smears for leishmania parasites were treated with sodium stibogluconate (each ml of injection containing the equivalent of 100 mg pentavalent antimony).
(15) FEV1 was recorded at regular intervals during the hour of provocation, and acid reflux (pH less than 4) was monitored by antimony pH electrodes in the esophagus.
(16) This difference could be corrected by a modified calibration, using the external skin reference electrode of the antimony electrode (finger calibration).
(17) When healed lesions of 14 of these subjects were re-biopsied 1 to 12 months after the end of pentavalent antimonial therapy, MHC class II antigens could no longer be seen on keratinocytes.
(18) Dogs naturally infected with Leishmania infantum Nicolle were treated with three courses of meglumine antimoniate.
(19) Lines expressing lmpgpA showed resistance to arsenite and trivalent antimonials, but not to pentavalent antimonials, zinc, cadmium, or the typical multidrug-resistant P-glycoprotein substrates vinblastine and puromycin.
(20) Therefore data recorded with antimony electrodes cannot be compared with those recorded with glass electrodes.