(1) The ability of TSH to regulate each in an antiparallel manner is atypical.
(2) The first contains only antiparallel beta-segments, the second "mixed" beta-segments, with some strands lying antiparallel and others parallel.
(3) Important secondary structure elements that can be derived from the observed nuclear Overhauser effects are a large antiparallel beta-pleated sheet consisting of four strands, A, B, C, D, a segment SAB consisting of an extended region around the active-center histidine (His-15) and an alpha-helix, a half-turn between strands B and C, a segment SCD which shows no typical secondary structure, and the alpha-helical, C-terminal segment S(term).
(4) There is a further possibility of formation of an antiparallel sheet structure between the insulin and receptor molecules in the complex similar to that between monomers in the insulin dimer.
(5) The refined structures are comprised of a C-terminal alpha-helix, a small segment of antiparallel beta-sheet, and several loops.
(6) This was ascribed to the formation of a triple helix involving two 1,10-phenanthroline-octathymidylate strands that adopt an antiparallel orientation with respect to each other.
(7) In both the light- and heavy-chain variable domains, the stereochemistry of five structurally conserved sites general to all known antibody structures matched that of the zinc ligands of carbonic anhydrase: three residues on two hydrogen-bonded antiparallel beta-strands.
(8) The theory is developed for intramolecular beta-structure, but it can also explain the overall features of intermolecular beta-folding; it is applicable both to antiparallel and parallel beta-sheets.
(9) Monomer-monomer contacts involve antiparallel beta-sheet interactions, which form a dimer with two layers of eight beta-strands.
(10) Common features of the solution structure and the two crystal structures are the four-stranded beta-structure, composed of a pair of parallel strands, and three pairs of antiparallel beta-strands flanked on one side by a 12-residue alpha-helix and on the other side by a loop containing the serine proteinase binding site.
(11) The dimers are predominantly antiparallel and nearly in register, as judged by antibody labeling.
(12) The regular secondary structure includes two and a half turns of alpha-helix running from residues 21 to 30 and a three-stranded antiparallel beta-sheet including peptides 3-5, 34-38, and 41-46.
(13) On the basis of the secondary structure calculations from the known amino acid sequence we came to the conclusion that hepatitis A virus capsid proteins have the typical antiparallel beta-sheet bilayer structure.
(14) Each domain is composed of two motifs with the 'Greek key' topology which form a pair of four-stranded beta-sheets with an antiparallel packing.
(15) A novel 282-residue extension contains repeats of approximately 29 amino acid residues predicted to have an antiparallel beta-sheet structure, followed by a glycine-rich sequence.
(16) The polypeptide crystallizes from ethanol as a left-handed, double-stranded, antiparallel beta 5.6-helical dimer that is 31 A long and an average of 4.8 A in diameter.
(17) As shown in a companion paper (Rippe et al., 1989), the two combinations D1.D3 and D2.D4 form normal antiparallel duplexes, whereas the pairs D1.D2 and D3.D4 constitute duplexes with the same sequences, but with the two strands parallel to each other.
(18) Contrary to assertions by Makinen & Sigountos (1984), our results unambigously demonstrate that adjacent rows of double strands in macrofibers are oriented in an antiparallel manner, as in the Wishner-Love crystal.
(19) Oxidized glutaredoxin contains a four-stranded beta-sheet, with the peripheral strand 32-37 arranged parallel to the strand 2-7, which further combines with the two additional strands 61-64 and 67-69 in an antiparallel fashion.
(20) By overlapping two photographic transparencies of the polar paracrystal antiparallel, directly observed images of polymorphic bipolar paracrystals could be synthesized photographically with fidelity.
Line
Definition:
(n.) Flax; linen.
(n.) The longer and finer fiber of flax.
(v. t.) To cover the inner surface of; as, to line a cloak with silk or fur; to line a box with paper or tin.
(v. t.) To put something in the inside of; to fill; to supply, as a purse with money.
(v. t.) To place persons or things along the side of for security or defense; to strengthen by adding anything; to fortify; as, to line works with soldiers.
(v. t.) To impregnate; -- applied to brute animals.
(n.) A linen thread or string; a slender, strong cord; also, a cord of any thickness; a rope; a hawser; as, a fishing line; a line for snaring birds; a clothesline; a towline.
(n.) A more or less threadlike mark of pen, pencil, or graver; any long mark; as, a chalk line.
(n.) The course followed by anything in motion; hence, a road or route; as, the arrow descended in a curved line; the place is remote from lines of travel.
(n.) Direction; as, the line of sight or vision.
(n.) A row of letters, words, etc., written or printed; esp., a row of words extending across a page or column.
(n.) A short letter; a note; as, a line from a friend.
(n.) A verse, or the words which form a certain number of feet, according to the measure.
(n.) Course of conduct, thought, occupation, or policy; method of argument; department of industry, trade, or intellectual activity.
(n.) That which has length, but not breadth or thickness.
(n.) The exterior limit of a figure, plat, or territory; boundary; contour; outline.
(n.) A threadlike crease marking the face or the hand; hence, characteristic mark.
(n.) Lineament; feature; figure.
(n.) A straight row; a continued series or rank; as, a line of houses, or of soldiers; a line of barriers.
(n.) A series or succession of ancestors or descendants of a given person; a family or race; as, the ascending or descending line; the line of descent; the male line; a line of kings.
(n.) A connected series of public conveyances, and hence, an established arrangement for forwarding merchandise, etc.; as, a line of stages; an express line.
(n.) A circle of latitude or of longitude, as represented on a map.
(n.) The equator; -- usually called the line, or equinoctial line; as, to cross the line.
(n.) A long tape, or a narrow ribbon of steel, etc., marked with subdivisions, as feet and inches, for measuring; a tapeline.
(n.) A measuring line or cord.
(n.) That which was measured by a line, as a field or any piece of land set apart; hence, allotted place of abode.
(n.) Instruction; doctrine.
(n.) The proper relative position or adjustment of parts, not as to design or proportion, but with reference to smooth working; as, the engine is in line or out of line.
(n.) The track and roadbed of a railway; railroad.
(n.) A row of men who are abreast of one another, whether side by side or some distance apart; -- opposed to column.
(n.) The regular infantry of an army, as distinguished from militia, guards, volunteer corps, cavalry, artillery, etc.
(n.) A trench or rampart.
(n.) Dispositions made to cover extended positions, and presenting a front in but one direction to an enemy.
(n.) Form of a vessel as shown by the outlines of vertical, horizontal, and oblique sections.
(n.) One of the straight horizontal and parallel prolonged strokes on and between which the notes are placed.
(n.) A number of shares taken by a jobber.
(n.) A series of various qualities and values of the same general class of articles; as, a full line of hosiery; a line of merinos, etc.
(n.) The wire connecting one telegraphic station with another, or the whole of a system of telegraph wires under one management and name.
(n.) The reins with which a horse is guided by his driver.
(n.) A measure of length; one twelfth of an inch.
(v. t.) To mark with a line or lines; to cover with lines; as, to line a copy book.
(v. t.) To represent by lines; to delineate; to portray.
(v. t.) To read or repeat line by line; as, to line out a hymn.
(v. t.) To form into a line; to align; as, to line troops.
Example Sentences:
(1) Similar experimental manipulation has yielded in vitro lines established from avian B-cell lymphomas expressing elevated levels of c-myc or v-rel.
(2) The effect of insulin-like growth factor I (IGF-I) on growth of small cell lung cancer (SCLC) cell lines was studied.
(3) The liver metastasis was produced by intrasplenic injection of the fluid containing of KATOIII in nude mouse and new cell line was established using the cells of metastatic site.
(4) After stimulation with lipopolysaccharide and calcium ionophore A23187, culture supernatants of clones c18A and c29A showed cytotoxic activity against human melanoma A375 Met-Mix and other cell lines which were resistant to the tumor necrosis factor, lymphotoxin and interleukin 1.
(5) The predicted non-Lorentzian line shapes and widths were found to be in good agreement with experimental results, indicating that the local orientational order (called "packing" by many workers) in the bilayers of small vesicles and in multilamellar membranes is substantially the same.
(6) On the other hand, human IL-9, which is a homologue to murine P40, was cloned from a cDNA library prepared with mRNA isolated from PHA-induced T-cell line (C5MJ2).
(7) However, four of ten young adult outer arm (relatively sun-exposed) and one of ten young adult inner arm (relatively sun-protected) fibroblasts lines increased their saturation density in response to retinoic acid.
(8) The promoters of the adenovirus 2 major late gene, the mouse beta-globin gene, the mouse immunoglobulin VH gene and the LTR of the human T-lymphotropic retrovirus type I were tested for their transcription activities in cell-free extracts of four cell lines; HeLa, CESS (Epstein-Barr virus-transformed human B cell line), MT-1 (HTLV-I-infected human T cell line without viral protein synthesis), and MT-2 (HTLV-I-infected human T cell line producing viral proteins).
(9) In contrast to L2 and L3 in L1 the mid gut runs down in a straight line without any looping.
(10) In addition, KM231 could detect a small amount of the antigen ganglioside in human gastric normal and cancerous mucosa and in gastric cancer cell lines by HPTLC-immunostaining.
(11) Taken together these results are consistent with the view that primary CTL, as well as long term cloned CTL cell lines, exercise their cytolytic activity by means of perforin.
(12) It is my desperate hope that we close out of town.” In the book, God publishes his own 'It Getteth Better' video and clarifies his original writings on homosexuality: I remember dictating these lines to Moses; and afterward looking up to find him staring at me in wide-eyed astonishment, and saying, "Thou do knowest that when the Israelites read this, they're going to lose their fucking shit, right?"
(13) The aetiological factors concerned in the production of paraumbilical and epigastric hernias have been reviewed along structural--functional lines.
(14) The antiproliferative activity of IFN was studied using the parental L cell line, a tk- derivative, and a tk- (tk+) subline into which the tk gene of herpes simplex virus was introduced.
(15) A murine keratinocyte cell line that is resistant to the growth-inhibitory effects of transforming growth factor beta 1 (TGF beta 1) was examined for differential gene expression patterns that may be related to the mechanism of the loss of TGF beta 1 responsiveness.
(16) "This was very strategic and it was in line of the ideology of the Bush administration which has been to put in place a free market and conservative agenda."
(17) Cell lines specific for class I or class II loci of the MHC produced interferon and colony-stimulating factors.
(18) Seven patients were treated with combination chemotherapy, consisting of CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) or MOPP (chloromethine, vincristine, procarbazine, prednisone), in some cases followed by non-cross-resistant second line chemotherapy, if no complete response was attained.
(19) Displacement of a colinear line over the same range without an offset evoked little, if any, response.
(20) N-Ethylmaleimide-sensitive 5'-nucleotide phosphodiesterase and alkaline phosphatase activities from other cell lines were also recovered in the cytosol.