(a.) Pertaining to the antipodes; situated on the opposite side of the globe.
(a.) Diametrically opposite.
Example Sentences:
(1) R-(+)-Nicotine is a substrate Km = 1.42 X 10(-5)M for an SAM-dependent guinea pig lung aromatic azaheterocycle N-methyltransferase, whereas S-(-)-nicotine acts as a competitive inhibitor (Ki = 6.25 X 10(-5)M) of the N-methylation of its antipode.
(2) The 5-HT depleting potency of (+)-MDMA was significantly greater than that of its (-)-antipode at 3 hr in PB pretreated, but not in SKF-525A pretreated animals.
(3) Potential in the Antipodes for production of unique and abundant fishery products is immense for both local and export markets.
(4) In general antipodals have maximum accumulation of physiologically active substances and intense activity of different enzymes.
(5) Since the transformation goes from the inactive to the pharmacologically active form, the (R)-enantiomer can be considered as a prodrug of its (S)-antipode.
(6) The determination of the enantiomeric composition of the excreted 2-phenylpropionic acid after a single oral dose indicated that the (R)-(-)-enantiomer given as such or in the racemate was inverted to its antipode, which strongly suggests that (S)-(+)-2-phenylpropionic acid is responsible for the inductive effects observed.
(7) The area under the concentration versus time curve values for the two enantiomers were approximately 10% higher for the (R)-antipode because of a slightly slower elimination of this compound.
(8) Both optical antipodes of the pivotal epoxy alcohol intermediate were prepared in 95% enantiomeric excess by the Sharpless epoxidation of a (Z)-allylic alcohol.
(9) Chiral analysis of the human renal epoxyeicosatrienoic acids shows the formation of 8,9-, 11,12- and 14,15-epoxyeicosatrienoic acids in a 1:1, 4:1 and 2:1 ratio of antipodes, respectively.
(10) The limit of determination for the L-antipode is ca.
(11) However, this stereoselectivity of action is not manifest in vivo, due to the thus-far-unique unidirectional metabolic inversion of the chiral centre from the inactive R(-)-isomers to the S(+)-antipodes.
(12) The summation of the results fully defines the overall stereochemistry of the coupled isomerization and cyclization of geranyl pyrophosphate to the antipodal pinenes.
(13) The Bernburg physician and pharmaceutist Bucholz became there for many years his consultee for questions of natural sciences; Gren, who also came from Bernburg, became the antipode in the dispute about problems of optics.
(14) 8a showed potent antifungal activity, while its antipode (+)-cis-2-ACPC (8b) had no activity.
(15) A novel approach to the optical resolution of racemic enones has been introduced by using the binding properties of the transport protein albumin, which chemically binds preferentially one antipode of some alpha, beta-unsaturated cyclic enones in a reversible manner.
(16) The model successfully: (1) explained the relative activity or inactivity of compounds such as cis- and trans-1-methyl-5-hydroxyl ATN derivatives and the corresponding cis- and trans-octohydrobenzo[f]quinolines; (2) predicted the more potent antipode of 2-aminoindan dopaminergic agonists; and (3) explained the structure--activity peculiarities of 3-(3-hydroxyphenyl)-N-alkylpiperidines in which the potency is increased for (3S)-isomers and decreased for (3R)-isomers when the N-alkyl group is greater than propyl.
(17) The three antipodal wave forms were displayed as a single 3-D Lissajous trajectory which contained four apices, corresponding to P40 (apex A), N70 (apex B), P100 (apex C) and N125 (apex D).
(18) Patch currents recorded at the soma cap, antipodal to the origin of the axon, and whole-cell currents were recorded simultaneously and normalized to membrane capacitance.
(19) Structures for such chirally symmetric organisms are outlined, as is the gradual decoupling of their integrated antipodal metabolisms upon an evolutionary progression from meso organism to racemic organism to racemate of organisms.
(20) A marked antipodal potency ratio was observed in strains TA100 and TA1535 when racemic and L-azidoalanine were compared.
Antipodean
Definition:
(a.) Pertaining to the antipodes, or the opposite side of the world; antipodal.
Example Sentences:
(1) And yet, by spotlighting how very far the brand has travelled under Sarah Burton in the post-Lee years, the Savage Beauty announcement, coming hot on the heels of the Antipodean tour, also flags up the contrasting identities that cohabit the McQueen brand.
(2) His accent is equally indeterminate - part Teeside where he grew up, part Hollywood where he mainly lives, plus a hint of antipodean which he must have caught from Russell Crowe.
(3) Australia and New Zealand have perhaps even stronger emotional and cultural links to Britain, but as the economies of Asia have risen, the antipodean nations have found themselves on the doorstep of the greatest manufacturing region on earth.
(4) Three cases of antipodean squint are reported without known etiology factor.
(5) Parallel features exist among diseases in Antipodean hosts when compared with those in other tropical and temperate regions.
(6) How this charismatic-if-potentially-stinky Antipodean reached rural England is anyone’s guess.
(7) The calamitous British-conceived campaign is seen as the birthplace of the core Antipodean values of endurance, heroism, sacrifice, humour and – above all – “mateship” or camaraderie.
(8) Antipodeans trade matey banter; purposeful Germans with trekking poles overtake on the straights; the French, beautifully turned out, shrug indifferently; fat tattooed Brits huff and puff on the inclines.
(9) The 78-year-old has spent a lifetime building the world's most powerful media group, transforming a single antipodean newspaper into an empire that transcends national boundaries.
(10) As if the regular distance wasn’t enough already, New Zealand’s World Cup qualifying play-off against Mexico on November 13 in Mexico City added an extra element of ‘antipodean traveller’ to the match.
(11) Henning Mankell, Lionel Shriver, Hanif Kureishi and the antipodean writers CK Stead, Thomas Keneally and Anna Funder are other globally renowned signatories.
(12) News Corp, which Murdoch built from a single antipodean newspaper , is home to the biggest-selling stable of newspapers in the English-speaking world, the Fox TV network and Fox News in the US, film studio 20th Century Fox which was responsible for the year's biggest hit Avatar , publishing house Harper Collins and satellite TV companies in Asia, Italy and Australia.
(13) In her 27-year political career, she has gained a reputation for being forthright – an antipodean Margaret Thatcher.
(14) It's the middle of the hot Antipodean summer, but when Stephen Elop comes into the room of journalists he's wearing his suit jacket.
(15) Apparently these cruises are very popular with Aussies – the other three boats were also Antipodean-heavy – who tend to weld them on to larger backpacking odysseys across Europe.
(16) A military debacle of epic proportions and a byword for poor planning and arrogant, incompetent top brass that would blight Churchill’s career for years, Gallipoli has become a cornerstone of Australian and New Zealand national pride, the birthplace of the core Antipodean values of pluck, endurance, heroism, sacrifice, dark humour and – above all – “mateship”.
(17) "The arrival of Flat White and the Antipodeans really was very important," Jeffrey Young of Allegra says.
(18) Foran, who joined Walmart from the antipodean retailer Woolworths in 2011, has been working in retail for 35 years, having started his career as a teenage shelf stacker.
(19) "I like to always ask if someone is from New Zealand if they have a vaguely Antipodean accent, since if they're Australian they won't be offended, but if they actually are a Kiwi they'll be mightily impressed that for once someone hasn't assumed they are Australian.
(20) Using established actors (look out for some of Cave's Harry Potter co-stars) as well as her 14-year-old sister Bebe, these Antipodean antics are dry and poignant – Aunt Jocelyn never got over the death of her cat in 1978, while Mama Pru is a recovering gambling addict.