(a.) Pertaining to the antipodes; situated on the opposite side of the globe.
(a.) Diametrically opposite.
Example Sentences:
(1) R-(+)-Nicotine is a substrate Km = 1.42 X 10(-5)M for an SAM-dependent guinea pig lung aromatic azaheterocycle N-methyltransferase, whereas S-(-)-nicotine acts as a competitive inhibitor (Ki = 6.25 X 10(-5)M) of the N-methylation of its antipode.
(2) The 5-HT depleting potency of (+)-MDMA was significantly greater than that of its (-)-antipode at 3 hr in PB pretreated, but not in SKF-525A pretreated animals.
(3) Potential in the Antipodes for production of unique and abundant fishery products is immense for both local and export markets.
(4) In general antipodals have maximum accumulation of physiologically active substances and intense activity of different enzymes.
(5) Since the transformation goes from the inactive to the pharmacologically active form, the (R)-enantiomer can be considered as a prodrug of its (S)-antipode.
(6) The determination of the enantiomeric composition of the excreted 2-phenylpropionic acid after a single oral dose indicated that the (R)-(-)-enantiomer given as such or in the racemate was inverted to its antipode, which strongly suggests that (S)-(+)-2-phenylpropionic acid is responsible for the inductive effects observed.
(7) The area under the concentration versus time curve values for the two enantiomers were approximately 10% higher for the (R)-antipode because of a slightly slower elimination of this compound.
(8) Both optical antipodes of the pivotal epoxy alcohol intermediate were prepared in 95% enantiomeric excess by the Sharpless epoxidation of a (Z)-allylic alcohol.
(9) Chiral analysis of the human renal epoxyeicosatrienoic acids shows the formation of 8,9-, 11,12- and 14,15-epoxyeicosatrienoic acids in a 1:1, 4:1 and 2:1 ratio of antipodes, respectively.
(10) The limit of determination for the L-antipode is ca.
(11) However, this stereoselectivity of action is not manifest in vivo, due to the thus-far-unique unidirectional metabolic inversion of the chiral centre from the inactive R(-)-isomers to the S(+)-antipodes.
(12) The summation of the results fully defines the overall stereochemistry of the coupled isomerization and cyclization of geranyl pyrophosphate to the antipodal pinenes.
(13) The Bernburg physician and pharmaceutist Bucholz became there for many years his consultee for questions of natural sciences; Gren, who also came from Bernburg, became the antipode in the dispute about problems of optics.
(14) 8a showed potent antifungal activity, while its antipode (+)-cis-2-ACPC (8b) had no activity.
(15) A novel approach to the optical resolution of racemic enones has been introduced by using the binding properties of the transport protein albumin, which chemically binds preferentially one antipode of some alpha, beta-unsaturated cyclic enones in a reversible manner.
(16) The model successfully: (1) explained the relative activity or inactivity of compounds such as cis- and trans-1-methyl-5-hydroxyl ATN derivatives and the corresponding cis- and trans-octohydrobenzo[f]quinolines; (2) predicted the more potent antipode of 2-aminoindan dopaminergic agonists; and (3) explained the structure--activity peculiarities of 3-(3-hydroxyphenyl)-N-alkylpiperidines in which the potency is increased for (3S)-isomers and decreased for (3R)-isomers when the N-alkyl group is greater than propyl.
(17) The three antipodal wave forms were displayed as a single 3-D Lissajous trajectory which contained four apices, corresponding to P40 (apex A), N70 (apex B), P100 (apex C) and N125 (apex D).
(18) Patch currents recorded at the soma cap, antipodal to the origin of the axon, and whole-cell currents were recorded simultaneously and normalized to membrane capacitance.
(19) Structures for such chirally symmetric organisms are outlined, as is the gradual decoupling of their integrated antipodal metabolisms upon an evolutionary progression from meso organism to racemic organism to racemate of organisms.
(20) A marked antipodal potency ratio was observed in strains TA100 and TA1535 when racemic and L-azidoalanine were compared.
Cross
Definition:
(n.) A gibbet, consisting of two pieces of timber placed transversely upon one another, in various forms, as a T, or +, with the horizontal piece below the upper end of the upright, or as an X. It was anciently used in the execution of criminals.
(n.) The sign or mark of the cross, made with the finger, or in ink, etc., or actually represented in some material; the symbol of Christ's death; the ensign and chosen symbol of Christianity, of a Christian people, and of Christendom.
(n.) Affiction regarded as a test of patience or virtue; trial; disappointment; opposition; misfortune.
(n.) A piece of money stamped with the figure of a cross, also, that side of such a piece on which the cross is stamped; hence, money in general.
(n.) An appendage or ornament or anything in the form of a cross; a badge or ornamental device of the general shape of a cross; hence, such an ornament, even when varying considerably from that form; thus, the Cross of the British Order of St. George and St. Michael consists of a central medallion with seven arms radiating from it.
(n.) A monument in the form of a cross, or surmounted by a cross, set up in a public place; as, a market cross; a boundary cross; Charing Cross in London.
(n.) A common heraldic bearing, of which there are many varieties. See the Illustration, above.
(n.) The crosslike mark or symbol used instead of a signature by those unable to write.
(n.) Church lands.
(n.) A line drawn across or through another line.
(n.) A mixing of breeds or stock, especially in cattle breeding; or the product of such intermixture; a hybrid of any kind.
(n.) An instrument for laying of offsets perpendicular to the main course.
(n.) A pipe-fitting with four branches the axes of which usually form's right angle.
(a.) Not parallel; lying or falling athwart; transverse; oblique; intersecting.
(a.) Not accordant with what is wished or expected; interrupting; adverse; contrary; thwarting; perverse.
(a.) Characterized by, or in a state of, peevishness, fretfulness, or ill humor; as, a cross man or woman.
(a.) Made in an opposite direction, or an inverse relation; mutually inverse; interchanged; as, cross interrogatories; cross marriages, as when a brother and sister marry persons standing in the same relation to each other.
(prep.) Athwart; across.
(v. t.) To put across or athwart; to cause to intersect; as, to cross the arms.
(v. t.) To lay or draw something, as a line, across; as, to cross the letter t.
(v. t.) To pass from one side to the other of; to pass or move over; to traverse; as, to cross a stream.
(v. t.) To pass, as objects going in an opposite direction at the same time.
(v. t.) To run counter to; to thwart; to obstruct; to hinder; to clash or interfere with.
(v. t.) To interfere and cut off; to debar.
(v. t.) To make the sign of the cross upon; -- followed by the reflexive pronoun; as, he crossed himself.
(v. t.) To cancel by marking crosses on or over, or drawing a line across; to erase; -- usually with out, off, or over; as, to cross out a name.
(v. t.) To cause to interbreed; -- said of different stocks or races; to mix the breed of.
(v. i.) To lie or be athwart.
(v. i.) To move or pass from one side to the other, or from place to place; to make a transit; as, to cross from New York to Liverpool.
(v. i.) To be inconsistent.
(v. i.) To interbreed, as races; to mix distinct breeds.
Example Sentences:
(1) However, when cross-linked to anti-CD4 or anti-CD8 antibodies a markedly enhanced proliferation of the corresponding subpopulation is observed.
(2) The cross sectional area of the aortic lumen was gradually decreased while the length of the stenotic lesion gradually increased by using strips with different width.
(3) The quaternary structure of ribonucleotide reductase of Escherichia coli was investigated, with the use of purified B1 and B2 proteins and bifunctional cross-linking agents.
(4) Multiple overlapping thin 3D slab acquisition is presented as a magnitude contrast (time of flight) technique which combines advantages from multiple thin slice 2D and direct 3D volume acquisitions to obtain high-resolution cross-sectional images of vessel detail.
(5) The mobility on sodium dodecyl sulfate-polyacrylamide gel electrophoresis is anomalous since the undenatured, cross-linked proteins have the same Stokes radius as the native, uncross-linked alpha beta gamma heterotrimer.
(6) 10D1 mAb induced a substantial proliferation of peripheral blood T cells when cross-linked with goat anti-mouse Ig antibody.
(7) Mapping of the cross-link position between U2 and U6 RNAs is consistent with base-pairing between the 5' domain of U2 and the 3' end of U6 RNA.
(8) There was however no difference in the cross-sectional studies and no significant deleterious effect detected of tobacco use on forearm bone mineral content.
(9) Plasma for beta-endorphin assay was preincubated with sepharose-bound anti-beta-lipotropin to remove beta-lipotropin that cross-reacted with the beta-endorphin RIA.
(10) In crosses between inverted repeats, a single intrachromatid reciprocal exchange leads to inversion of the sequence between the crossover sites and recovery of both genes involved in the event.
(11) Further purification of ZAB by filtration through Sephadex G-100 gave a preparation (ZAB2) which contained the common antigen as shown by the cross-reactivity of anti-ZAB2 rat serum with seven stains of N. gonorrhoeae.
(12) On the other hand, as a cross-reference experiment, we developed a paper work test to do in the same way as on the VDT.
(13) No reversions to wild-type levels were observed in 555 heterozygous offspring of crosses between homozygous Campines and normals.
(14) No cross reactions were found between bluetongue and epizootic haemorrhagic disease of deer viruses.
(15) Seven patients were treated with combination chemotherapy, consisting of CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) or MOPP (chloromethine, vincristine, procarbazine, prednisone), in some cases followed by non-cross-resistant second line chemotherapy, if no complete response was attained.
(16) [125I]AaIT was shown to cross the midgut of Sarcophaga through a morphologically distinct segment of the midgut previously shown to be permeable to a cytotoxic, positively charged polypeptide of similar molecular weight.
(17) Blood was cross-matched preoperatively in 47.7% of patients and 90% of this blood was either not administered or given as a delayed nonurgent procedure.
(18) Conjugational recombination in Escherichia coli was investigated by monitoring synthesis of the lacZ+ product, beta-galactosidase, in crosses between lacZ mutants.
(19) Crossed immunoelectrophoresis and sucrose density gradient ultracentrifugation of the patient's plasma showed his prothrombin to be qualitatively indistinguishable from normal prothrombin by these techniques.
(20) Eighty micrograms of the topically active parasympatholytic drug ipratropium were applied intranasally four times daily in 20 adults with perennial rhinitis and severe watery rhinorrhoea in a double-blind controlled cross-over trial.