(a.) Pertaining to the antipodes; situated on the opposite side of the globe.
(a.) Diametrically opposite.
Example Sentences:
(1) R-(+)-Nicotine is a substrate Km = 1.42 X 10(-5)M for an SAM-dependent guinea pig lung aromatic azaheterocycle N-methyltransferase, whereas S-(-)-nicotine acts as a competitive inhibitor (Ki = 6.25 X 10(-5)M) of the N-methylation of its antipode.
(2) The 5-HT depleting potency of (+)-MDMA was significantly greater than that of its (-)-antipode at 3 hr in PB pretreated, but not in SKF-525A pretreated animals.
(3) Potential in the Antipodes for production of unique and abundant fishery products is immense for both local and export markets.
(4) In general antipodals have maximum accumulation of physiologically active substances and intense activity of different enzymes.
(5) Since the transformation goes from the inactive to the pharmacologically active form, the (R)-enantiomer can be considered as a prodrug of its (S)-antipode.
(6) The determination of the enantiomeric composition of the excreted 2-phenylpropionic acid after a single oral dose indicated that the (R)-(-)-enantiomer given as such or in the racemate was inverted to its antipode, which strongly suggests that (S)-(+)-2-phenylpropionic acid is responsible for the inductive effects observed.
(7) The area under the concentration versus time curve values for the two enantiomers were approximately 10% higher for the (R)-antipode because of a slightly slower elimination of this compound.
(8) Both optical antipodes of the pivotal epoxy alcohol intermediate were prepared in 95% enantiomeric excess by the Sharpless epoxidation of a (Z)-allylic alcohol.
(9) Chiral analysis of the human renal epoxyeicosatrienoic acids shows the formation of 8,9-, 11,12- and 14,15-epoxyeicosatrienoic acids in a 1:1, 4:1 and 2:1 ratio of antipodes, respectively.
(10) The limit of determination for the L-antipode is ca.
(11) However, this stereoselectivity of action is not manifest in vivo, due to the thus-far-unique unidirectional metabolic inversion of the chiral centre from the inactive R(-)-isomers to the S(+)-antipodes.
(12) The summation of the results fully defines the overall stereochemistry of the coupled isomerization and cyclization of geranyl pyrophosphate to the antipodal pinenes.
(13) The Bernburg physician and pharmaceutist Bucholz became there for many years his consultee for questions of natural sciences; Gren, who also came from Bernburg, became the antipode in the dispute about problems of optics.
(14) 8a showed potent antifungal activity, while its antipode (+)-cis-2-ACPC (8b) had no activity.
(15) A novel approach to the optical resolution of racemic enones has been introduced by using the binding properties of the transport protein albumin, which chemically binds preferentially one antipode of some alpha, beta-unsaturated cyclic enones in a reversible manner.
(16) The model successfully: (1) explained the relative activity or inactivity of compounds such as cis- and trans-1-methyl-5-hydroxyl ATN derivatives and the corresponding cis- and trans-octohydrobenzo[f]quinolines; (2) predicted the more potent antipode of 2-aminoindan dopaminergic agonists; and (3) explained the structure--activity peculiarities of 3-(3-hydroxyphenyl)-N-alkylpiperidines in which the potency is increased for (3S)-isomers and decreased for (3R)-isomers when the N-alkyl group is greater than propyl.
(17) The three antipodal wave forms were displayed as a single 3-D Lissajous trajectory which contained four apices, corresponding to P40 (apex A), N70 (apex B), P100 (apex C) and N125 (apex D).
(18) Patch currents recorded at the soma cap, antipodal to the origin of the axon, and whole-cell currents were recorded simultaneously and normalized to membrane capacitance.
(19) Structures for such chirally symmetric organisms are outlined, as is the gradual decoupling of their integrated antipodal metabolisms upon an evolutionary progression from meso organism to racemic organism to racemate of organisms.
(20) A marked antipodal potency ratio was observed in strains TA100 and TA1535 when racemic and L-azidoalanine were compared.
Globe
Definition:
(n.) A round or spherical body, solid or hollow; a body whose surface is in every part equidistant from the center; a ball; a sphere.
(n.) Anything which is nearly spherical or globular in shape; as, the globe of the eye; the globe of a lamp.
(n.) The earth; the terraqueous ball; -- usually preceded by the definite article.
(n.) A round model of the world; a spherical representation of the earth or heavens; as, a terrestrial or celestial globe; -- called also artificial globe.
(n.) A body of troops, or of men or animals, drawn up in a circle; -- a military formation used by the Romans, answering to the modern infantry square.
(v. t.) To gather or form into a globe.
Example Sentences:
(1) Over a period of 9 months a 12-year-old girl spontaneously developed a palpable cystic tumor in the upper eye lid which led to an indentation and downward displacement of the globe.
(2) "For a better world, not only for the Iranian people but for the next generation across the globe, I earnestly hope that President Rouhani will receive a warm welcome and meaningful responses during his visit to the UN."
(3) Lawmakers across the globe are beginning to recognize the need to deter this destructive conduct.
(4) The oblique interface between corneal and scleral stroma determines the appearance of the surgical limbus whose landmarks vary around the circumference of the globe but predictably correlate with structures of the anterior chamber angle.
(5) Levinson's film, to be titled Black Mass, will be based on the New York Times bestseller Black Mass: The True Story of an Unholy Alliance Between the FBI and the Irish Mob , by Boston Globe reporters Dick Lehr and Gerard O'Neill.
(6) In several other cases, MR provided information beyond that obtained with CT. MR has the advantage of providing exquisite anatomic detail in multiplanar images, and it appears to be more sensitive than CT in detecting small, subacute and chronic hemorrhage within soft-tissue masses in the orbit and in detecting ischemia of the globe.
(7) The relationships of age, gender, height, and weight to axial length of the globe were considered.
(8) The resection included the skin, globe, sphenoid wings, and orbitofrontal bone.
(9) Cat corneas were stored at refrigerator temperatures in M-K medium (TC-199, 5% dextran), modified M-K medium (TC-199, 1% chondroitin sulfate), or on the intact globe in moist chambers for intervals of one to nine days.
(10) The idea that these problems exist on the other side of the world, and that we Australians can ignore them by sheltering comfortably in our own sequestered corner of the globe, is a fool’s delusion.” Brandis sought to reach out to Australian Muslims, saying the threat came “principally from a small number of people among us who try to justify criminal acts by perverting the meaning of Islam”.
(11) That he was able to keep his secret treasures here, not in some remote corner of the globe but in the centre of the city that gave birth to the National Socialist movement, is both extraordinary and not short of a certain dark irony.
(12) He said: “We have seen a huge increase in the amount of inquiries and activities across the globe.
(13) The method is especially suited for the treatment of detachments in globes with posterior staphylomas.
(14) The UK-Colombia bilateral investment treaty is one of thousands criss-crossing the globe but is the first Britain will have ratified since 2009.
(15) And it has left the international community floundering as it tries to respond to conflicts spilling across the globe.
(16) In a long piece on the Daily Beast, he also revealed that Mia Farrow had granted permission for her image to be used in film clips honouring Allen during the Golden Globes, and expressed surprise at her Twitter reaction.
(17) It represents something of a vindication for Spielberg whose last high-minded awards contender, the first-world-war drama War Horse, failed to win anything at the last edition of either the Globes or the Oscars.
(18) "I don't think it will come as any surprise to anyone that the government is looking for alternative options and there certainly will be other players around the globe interested in this particular plant," Swinney told the BBC's Good Morning Scotland programme.
(19) Artists round the globe may plead free speech, but to treat the Pussy Riot gesture as a glorious stand for artistic liberty is like praising Johnny Rotten, who did similar things, as the Voltaire of our day.
(20) Significantly, the one thing that is making him worry is the Globe's stipulation that no English should be used – something that takes little account of how in India language itself has become globalised, along with so much else.