(a.) Pertaining to the antipodes; situated on the opposite side of the globe.
(a.) Diametrically opposite.
Example Sentences:
(1) R-(+)-Nicotine is a substrate Km = 1.42 X 10(-5)M for an SAM-dependent guinea pig lung aromatic azaheterocycle N-methyltransferase, whereas S-(-)-nicotine acts as a competitive inhibitor (Ki = 6.25 X 10(-5)M) of the N-methylation of its antipode.
(2) The 5-HT depleting potency of (+)-MDMA was significantly greater than that of its (-)-antipode at 3 hr in PB pretreated, but not in SKF-525A pretreated animals.
(3) Potential in the Antipodes for production of unique and abundant fishery products is immense for both local and export markets.
(4) In general antipodals have maximum accumulation of physiologically active substances and intense activity of different enzymes.
(5) Since the transformation goes from the inactive to the pharmacologically active form, the (R)-enantiomer can be considered as a prodrug of its (S)-antipode.
(6) The determination of the enantiomeric composition of the excreted 2-phenylpropionic acid after a single oral dose indicated that the (R)-(-)-enantiomer given as such or in the racemate was inverted to its antipode, which strongly suggests that (S)-(+)-2-phenylpropionic acid is responsible for the inductive effects observed.
(7) The area under the concentration versus time curve values for the two enantiomers were approximately 10% higher for the (R)-antipode because of a slightly slower elimination of this compound.
(8) Both optical antipodes of the pivotal epoxy alcohol intermediate were prepared in 95% enantiomeric excess by the Sharpless epoxidation of a (Z)-allylic alcohol.
(9) Chiral analysis of the human renal epoxyeicosatrienoic acids shows the formation of 8,9-, 11,12- and 14,15-epoxyeicosatrienoic acids in a 1:1, 4:1 and 2:1 ratio of antipodes, respectively.
(10) The limit of determination for the L-antipode is ca.
(11) However, this stereoselectivity of action is not manifest in vivo, due to the thus-far-unique unidirectional metabolic inversion of the chiral centre from the inactive R(-)-isomers to the S(+)-antipodes.
(12) The summation of the results fully defines the overall stereochemistry of the coupled isomerization and cyclization of geranyl pyrophosphate to the antipodal pinenes.
(13) The Bernburg physician and pharmaceutist Bucholz became there for many years his consultee for questions of natural sciences; Gren, who also came from Bernburg, became the antipode in the dispute about problems of optics.
(14) 8a showed potent antifungal activity, while its antipode (+)-cis-2-ACPC (8b) had no activity.
(15) A novel approach to the optical resolution of racemic enones has been introduced by using the binding properties of the transport protein albumin, which chemically binds preferentially one antipode of some alpha, beta-unsaturated cyclic enones in a reversible manner.
(16) The model successfully: (1) explained the relative activity or inactivity of compounds such as cis- and trans-1-methyl-5-hydroxyl ATN derivatives and the corresponding cis- and trans-octohydrobenzo[f]quinolines; (2) predicted the more potent antipode of 2-aminoindan dopaminergic agonists; and (3) explained the structure--activity peculiarities of 3-(3-hydroxyphenyl)-N-alkylpiperidines in which the potency is increased for (3S)-isomers and decreased for (3R)-isomers when the N-alkyl group is greater than propyl.
(17) The three antipodal wave forms were displayed as a single 3-D Lissajous trajectory which contained four apices, corresponding to P40 (apex A), N70 (apex B), P100 (apex C) and N125 (apex D).
(18) Patch currents recorded at the soma cap, antipodal to the origin of the axon, and whole-cell currents were recorded simultaneously and normalized to membrane capacitance.
(19) Structures for such chirally symmetric organisms are outlined, as is the gradual decoupling of their integrated antipodal metabolisms upon an evolutionary progression from meso organism to racemic organism to racemate of organisms.
(20) A marked antipodal potency ratio was observed in strains TA100 and TA1535 when racemic and L-azidoalanine were compared.
Opposite
Definition:
(a.) Placed over against; standing or situated over against or in front; facing; -- often with to; as, a house opposite to the Exchange.
(a.) Applied to the other of two things which are entirely different; other; as, the opposite sex; the opposite extreme.
(a.) Set over against each other, but separated by the whole diameter of the stem, as two leaves at the same node.
(a.) Placed directly in front of another part or organ, as a stamen which stands before a petal.
(n.) One who opposes; an opponent; an antagonist.
(n.) That which is opposed or contrary; as, sweetness and its opposite.
Example Sentences:
(1) "Zayani reportedly cited the political sensitivity of naturalising Sunni expatriates and wanted to avoid provoking the opposition," the embassy said.
(2) A triphasic pattern was evident for the neck moments including a small phase which represented a seating of the headform on the nodding blocks of the uppermost ATD neck segment, and two larger phases of opposite polarity which represented the motion of the head relative to the trunk during the first 350 ms after impact.
(3) Eye movements which were either complementary or in opposition to the induced vestibular nystagmus were produced with an optokinetic drum.
(4) Enamel was exclusively present opposite well developed dentine.
(5) She knows you can’t force the opposition to submit to your point of view.
(6) Problems associated with school-based clinics include vehement opposition to sex education, financing, and the sheer magnitude of the adolescents' health needs.
(7) Environment groups Environment groups that have strongly backed low-carbon power have barely wavered in their opposition to nuclear in the last decade, although their arguments now are now much about the cost than the danger it might pose.
(8) 10 women in the study developed carcinoma in the same or opposite breast within 16-20 years, a rate of incidence 480% greater than among the general population of women of the same age.
(9) To understand the reason for the opposite effect of the molar ratio observed at the middle of and at four residues away from the lysine-rich sequence, actual cross-linked residue(s) was (were) determined by subjecting cross-linked product to a protein sequencer.
(10) Effective medical or surgical therapy increased DAO activity and decreased CDAI, while clinical recurrence had the opposite effect.
(11) Hfr strains B4 and B8 transfer the Escherichia coli chromosome in opposite directions, each transferring lac(+) as the last known marker.
(12) Others said it might appeal to Russia, Assad's chief ally, which backs talks between the regime and the opposition.
(13) The ruling centre-right coalition government of Angela Merkel was dealt a blow by voters in a critical regional election on Sunday after the centre-left opposition secured a wafer-thin victory, setting the scene for a tension-filled national election in the autumn when everything will be up for grabs.
(14) Application of a mirror at the serosal surface opposite to the probe, resulted in an average increase of the output signal by 50% using the large fibre diameter probe, whereas no increase was observed with the small fibre probe.
(15) Her speech suggested the kind of Republican who would truly "raise the conversation", and if it seems like settling to want an opposition party to simply not be so utterly vindictive, well, yes, I will settle for that.
(16) 2) Left-right PHR coherence spectra had no distinct peaks, indicating that correlations between opposite PHR discharges were now not frequency specific.
(17) What we see from those opposite and we see in this chamber every day is the 'born to rule mentality' of those opposite.
(18) Of those, 39 were civilians, 34 armed opposition fighters and 35 members of the state security forces, said the UK-based group.
(19) Opposition politicians such as Joshua Benjamin Jeyaretnam and Chee Soon Juan , brought low for daring to disagree.
(20) A property may be considered overcrowded if two children above 10 of the opposite sex have to share the same bedroom.