(n.) One of the antipodes; anything exactly opposite.
Example Sentences:
(1) R-(+)-Nicotine is a substrate Km = 1.42 X 10(-5)M for an SAM-dependent guinea pig lung aromatic azaheterocycle N-methyltransferase, whereas S-(-)-nicotine acts as a competitive inhibitor (Ki = 6.25 X 10(-5)M) of the N-methylation of its antipode.
(2) The 5-HT depleting potency of (+)-MDMA was significantly greater than that of its (-)-antipode at 3 hr in PB pretreated, but not in SKF-525A pretreated animals.
(3) Potential in the Antipodes for production of unique and abundant fishery products is immense for both local and export markets.
(4) In general antipodals have maximum accumulation of physiologically active substances and intense activity of different enzymes.
(5) Since the transformation goes from the inactive to the pharmacologically active form, the (R)-enantiomer can be considered as a prodrug of its (S)-antipode.
(6) The determination of the enantiomeric composition of the excreted 2-phenylpropionic acid after a single oral dose indicated that the (R)-(-)-enantiomer given as such or in the racemate was inverted to its antipode, which strongly suggests that (S)-(+)-2-phenylpropionic acid is responsible for the inductive effects observed.
(7) The area under the concentration versus time curve values for the two enantiomers were approximately 10% higher for the (R)-antipode because of a slightly slower elimination of this compound.
(8) Both optical antipodes of the pivotal epoxy alcohol intermediate were prepared in 95% enantiomeric excess by the Sharpless epoxidation of a (Z)-allylic alcohol.
(9) Chiral analysis of the human renal epoxyeicosatrienoic acids shows the formation of 8,9-, 11,12- and 14,15-epoxyeicosatrienoic acids in a 1:1, 4:1 and 2:1 ratio of antipodes, respectively.
(10) The limit of determination for the L-antipode is ca.
(11) However, this stereoselectivity of action is not manifest in vivo, due to the thus-far-unique unidirectional metabolic inversion of the chiral centre from the inactive R(-)-isomers to the S(+)-antipodes.
(12) The summation of the results fully defines the overall stereochemistry of the coupled isomerization and cyclization of geranyl pyrophosphate to the antipodal pinenes.
(13) The Bernburg physician and pharmaceutist Bucholz became there for many years his consultee for questions of natural sciences; Gren, who also came from Bernburg, became the antipode in the dispute about problems of optics.
(14) 8a showed potent antifungal activity, while its antipode (+)-cis-2-ACPC (8b) had no activity.
(15) A novel approach to the optical resolution of racemic enones has been introduced by using the binding properties of the transport protein albumin, which chemically binds preferentially one antipode of some alpha, beta-unsaturated cyclic enones in a reversible manner.
(16) The model successfully: (1) explained the relative activity or inactivity of compounds such as cis- and trans-1-methyl-5-hydroxyl ATN derivatives and the corresponding cis- and trans-octohydrobenzo[f]quinolines; (2) predicted the more potent antipode of 2-aminoindan dopaminergic agonists; and (3) explained the structure--activity peculiarities of 3-(3-hydroxyphenyl)-N-alkylpiperidines in which the potency is increased for (3S)-isomers and decreased for (3R)-isomers when the N-alkyl group is greater than propyl.
(17) The three antipodal wave forms were displayed as a single 3-D Lissajous trajectory which contained four apices, corresponding to P40 (apex A), N70 (apex B), P100 (apex C) and N125 (apex D).
(18) Patch currents recorded at the soma cap, antipodal to the origin of the axon, and whole-cell currents were recorded simultaneously and normalized to membrane capacitance.
(19) Structures for such chirally symmetric organisms are outlined, as is the gradual decoupling of their integrated antipodal metabolisms upon an evolutionary progression from meso organism to racemic organism to racemate of organisms.
(20) A marked antipodal potency ratio was observed in strains TA100 and TA1535 when racemic and L-azidoalanine were compared.
Opposed
Definition:
(imp. & p. p.) of Oppose
Example Sentences:
(1) A study revealed that the percentage of active sperm in semen 30 seconds after ejaculation was 10.3% when a nonoxynol 9 latex condom was used as opposed to 55.9% in a nonspermicidal condom.
(2) Biden will meet with representatives from six gun groups on Thursday, including the NRA and the Independent Firearms Owners Association, which are both publicly opposed to stricter gun-control laws.
(3) The results indicated that smoke, as opposed to sham puffs, significantly reduced reports of cigarette craving, and local anesthesia significantly blocked this immediate reduction in craving produced by smoke inhalation.
(4) 3) The magnitude of K+ release is the ratio of two opposing mechanisms, a passive efflux and an active reuptake.
(5) We are firmly opposed to that," an unidentified spokesman from the ministry of industry and information technology told the state news agency, Xinhua.
(6) Each axon had a characteristic head position which was maximally excitatory to it, and a diametrically opposed head position which was minimally excitatory.3.
(7) As opposed to the other tests for LPD, awareness of the usefulness of the biopsy has increased as we have learned more about CL physiology.
(8) Strict fundamentalists oppose music in any form as a sensual distraction - the Taliban, of course, banned music in Afghanistan.
(9) The interaction between PE and E-IgG involved the extension of micropseudopods toward adherent E-IgG, the formation of a linear uniform cap of roughly 200 A between opposing cell membranes, the ingestion of E-IgG by PE into a membrane-lined compartment, and the disintegration of the ingested ligand into membranous debris.
(10) It is contended that the latter is the main factor in its production as opposed to the more common external rotation variety.
(11) Loyalists are opposed to any restrictions and have blocked roads and rioted over the issue.
(12) But today, Americans increasingly no longer shy away from saying they oppose mosques on the grounds that Muslims are a threat or different.
(13) In contrast, large territories may reflect widespread motor-unit actions, advantageous in force development where fine movement control is less important, as in biting in the intercuspal position or opposing gravity.
(14) Burns has a successful track record of opposing fees.
(16) And in terms of genuine defence needs (as opposed to state militarism), what greater known threat is there to human security than the prospect of runaway climate change?
(17) As opposed to nifedipine charybdotoxin shows no effect if added 18 h after the initiation of the activation process.
(18) RR spectra of fatty acyl-CoA and its complexes are consistent with the previous hypothesis that visible spectral shifts observed during formation of acetoacetyl-CoA and crotonyl-CoA complexes of fatty acyl-CoA dehydrogenase result from charge-transfer interactions in which the ground state is essentially nonbonding as opposed to interactions in which complete electron transfer occurs to form FAD semiquinone.
(19) The remarks are the most direct official response on the issue, although the government has previously said that it "resolutely opposes" hacking and criticised "baseless" claims.
(20) A lawyer advising one of the newspaper groups opposing the deal said: "All the regulator has to prove is that there is a potential for a reduction in plurality in the UK.