(n.) Those who live on the side of the globe diametrically opposite.
(n.) The country of those who live on the opposite side of the globe.
(n.) Anything exactly opposite or contrary.
Example Sentences:
(1) R-(+)-Nicotine is a substrate Km = 1.42 X 10(-5)M for an SAM-dependent guinea pig lung aromatic azaheterocycle N-methyltransferase, whereas S-(-)-nicotine acts as a competitive inhibitor (Ki = 6.25 X 10(-5)M) of the N-methylation of its antipode.
(2) The 5-HT depleting potency of (+)-MDMA was significantly greater than that of its (-)-antipode at 3 hr in PB pretreated, but not in SKF-525A pretreated animals.
(3) Potential in the Antipodes for production of unique and abundant fishery products is immense for both local and export markets.
(4) In general antipodals have maximum accumulation of physiologically active substances and intense activity of different enzymes.
(5) Since the transformation goes from the inactive to the pharmacologically active form, the (R)-enantiomer can be considered as a prodrug of its (S)-antipode.
(6) The determination of the enantiomeric composition of the excreted 2-phenylpropionic acid after a single oral dose indicated that the (R)-(-)-enantiomer given as such or in the racemate was inverted to its antipode, which strongly suggests that (S)-(+)-2-phenylpropionic acid is responsible for the inductive effects observed.
(7) The area under the concentration versus time curve values for the two enantiomers were approximately 10% higher for the (R)-antipode because of a slightly slower elimination of this compound.
(8) Both optical antipodes of the pivotal epoxy alcohol intermediate were prepared in 95% enantiomeric excess by the Sharpless epoxidation of a (Z)-allylic alcohol.
(9) Chiral analysis of the human renal epoxyeicosatrienoic acids shows the formation of 8,9-, 11,12- and 14,15-epoxyeicosatrienoic acids in a 1:1, 4:1 and 2:1 ratio of antipodes, respectively.
(10) The limit of determination for the L-antipode is ca.
(11) However, this stereoselectivity of action is not manifest in vivo, due to the thus-far-unique unidirectional metabolic inversion of the chiral centre from the inactive R(-)-isomers to the S(+)-antipodes.
(12) The summation of the results fully defines the overall stereochemistry of the coupled isomerization and cyclization of geranyl pyrophosphate to the antipodal pinenes.
(13) The Bernburg physician and pharmaceutist Bucholz became there for many years his consultee for questions of natural sciences; Gren, who also came from Bernburg, became the antipode in the dispute about problems of optics.
(14) 8a showed potent antifungal activity, while its antipode (+)-cis-2-ACPC (8b) had no activity.
(15) A novel approach to the optical resolution of racemic enones has been introduced by using the binding properties of the transport protein albumin, which chemically binds preferentially one antipode of some alpha, beta-unsaturated cyclic enones in a reversible manner.
(16) The model successfully: (1) explained the relative activity or inactivity of compounds such as cis- and trans-1-methyl-5-hydroxyl ATN derivatives and the corresponding cis- and trans-octohydrobenzo[f]quinolines; (2) predicted the more potent antipode of 2-aminoindan dopaminergic agonists; and (3) explained the structure--activity peculiarities of 3-(3-hydroxyphenyl)-N-alkylpiperidines in which the potency is increased for (3S)-isomers and decreased for (3R)-isomers when the N-alkyl group is greater than propyl.
(17) The three antipodal wave forms were displayed as a single 3-D Lissajous trajectory which contained four apices, corresponding to P40 (apex A), N70 (apex B), P100 (apex C) and N125 (apex D).
(18) Patch currents recorded at the soma cap, antipodal to the origin of the axon, and whole-cell currents were recorded simultaneously and normalized to membrane capacitance.
(19) Structures for such chirally symmetric organisms are outlined, as is the gradual decoupling of their integrated antipodal metabolisms upon an evolutionary progression from meso organism to racemic organism to racemate of organisms.
(20) A marked antipodal potency ratio was observed in strains TA100 and TA1535 when racemic and L-azidoalanine were compared.
Antithesis
Definition:
(n.) An opposition or contrast of words or sentiments occurring in the same sentence; as, "The prodigal robs his heir; the miser robs himself." "He had covertly shot at Cromwell; he how openly aimed at the Queen."
(n.) The second of two clauses forming an antithesis.
(n.) Opposition; contrast.
Example Sentences:
(1) If he’s being charged with publishing false information that seems to be the antithesis of his practice.” Bahgat writes a daily press review for Mada Masr as well as investigative pieces.
(2) The phychological aspects of language show an antithesis between learned and profane languages.
(3) "I got interested in writing about police corruption , it was a different angle, a police version of Bodies: very grown-up, it had mature themes, an antithesis of the escapist cop show.
(4) Mrs Tsvangirai was widely respected in Zimbabwe as the antithesis of President Robert Mugabe's extravagant and free-spending wife, Grace, who showed little concern for the plight of the many hungry and poor in her country.
(5) Ford, to them, is the antithesis of all that liberal namby-pambyness: he's the ordinary working man (albeit one who buys crack) and a good family guy (albeit one who has been repeatedly accused of sexual harassment and who, when asked if he ever told a colleague he wanted to "eat her pussy" he replied that he has "plenty enough to eat at home").
(6) "It is the very antithesis of big data, where you collect every bit of information that you can get hold of and send the lot to a processing centre, which gets clogged up in the process.
(7) In several of these neutrophil abnormalities, ie, neutrophil actin dysfunction, Chédiak-Higashi syndrome, and its "antithesis" described by Gallin and co-workers, the cellular dysfunctions were well documented but the molecular basis was completely obscure prior to cell biologic analysis.
(8) No: the clear winner in this elite-loathing, privilege-hating, populism-riven island is surely the quiet billionaire: Jonathan Harold Esmond Vere Harmsworth, 4th Viscount Rothermere , who emerges ever more obviously as the very antithesis of Lord C. He runs a successful, increasingly diversified business empire.
(9) The investment arm of UK-based Aviva, which manages assets worth $522bn, is the latest international financier to flag concerns over the Carmichael coalmine , which it said could become a “stranded asset” and was “the antithesis of what was needed” ahead of key UN climate talks in Paris in December.
(10) With the Somali women who were the antithesis of the stereotyped, subjugated Muslim female – strong, proud, fighters to the end.
(11) Juventus were rocked when Antonio Conte quit last summer, and further stunned when he was replaced by Allegri, who was fired by Milan months earlier and appeared to be the antithesis of the beloved former coach.
(12) A new nuclear arms race, new states possessing nuclear weapons, and a breakdown of the nonproliferation regime are the antithesis of those goals.
(13) They are the antithesis of the right therapeutics of obesities.
(14) Experiments leading to these conclusions were discussed, the heterogeneity of accessory immune cells is shown, and as an antithesis the possibility emerges that processing is not conditio sine qua non.
(15) And now it’s become the phenomenon that it is.” McKerrow said the show was the “antithesis” of all the norms of a competitive reality TV show.
(16) But they are also the antithesis of conventional political organisation.
(17) The "cot-death syndrome" model is a definition of a non-reality and the antithesis of a scientific model.
(18) Issa's look is the antithesis of fashion eccentrics such as Anna Dello Russo, and has real-life appeal.
(19) I interviewed G-Unit once (minus the banged-up Tony Yayo) and they were the antithesis of the sullen, aggressive rapper stereotype (although they did turn their noses up at the very idea of letting any of the "British food" at their 5-star hotel pass their lips, and sent their manager out for a McDonalds instead).
(20) The sentencing judge told him that he had indulged in “the antithesis of democracy”.