(1) Side effect incidence in patients treated with the paracetamol-sobrerol combination (3.7%) was significantly lower than that observed in subjects treated with paracetamol (6.1% - P less than 0.01), salicylics (25.1% - P less than 0.001), pyrazolics (12.6% - P less than 0.001), propionics (20.3%, P less than 0.001) or other antipyretics (17.9% - P less than 0.001).
(2) The results show that both drugs possess sedative, antispasmodic, antipyretic, antiinflammatory, cardiotonic and hypotensive effects, the strength of effect and toxicity being similar.
(3) The effects of continuous illumination, adrenalectomy and induction or inhibition of microsomal enzymes on antipyretic action of phenacetin were evaluated.
(4) This compound did not affect normal body temperature of rabbits and rats, this observation being similar to that noted with antipyretic analgesics and nonsteroidal anti-inflammatory agents.
(5) The compounds were subjected to pharmacological screening, and some were found to possess antiinflammatory and antipyretic properties.
(6) Since prostaglandins (PG) are known to potentiate (facilitate) the peripheral effects of BK and display a hyperthermic action, their synthesis being inhibited by antipyretics, we studied the effect of indomethacin and paracetamol on the BK-induced rise in rectal temperature in rabbits.
(7) Decrease in Te induced by hypothalamic cooling was also reversed by the intravenous injection of antipyretics.
(8) The benzisothiazoliltetrazoles showed high antipyretic activity and each tetrazole, except one, was appreciably more potent than the corresponding acid.
(9) Pyridyl-biphenylyl-acetamide (diphenpyramide, Z-876) is a new bisphenylalcanoic derivative with marked anti-inflammatory, analgesic, antipyretic and uricosuric properties.
(10) Paracetamol may be recommended as a safe analgesic-antipyretic during pregnancy and labour.
(11) The influence of initial temperature on the magnitude of the response to an antipyretic drug is a previously unappreciated finding with potential impact on pharmacodynamic investigations of antipyretic medications.
(12) Antipyretic and analgesic effects for dapsone have been demonstrated and are similar to those produced by phenylbutazone.
(13) A series of acyloxy- and alkyloxymethyl esters of meclofenamic, flufenamic and mefenamic acids has been synthesized and its antiinflammatory, analgesic and antipyretic activities have been compared with those of the corresponding acids and the methyl, beta,gamma-isopropylidene-dioxypropyl, N,N-diethylaminoethyl esters.
(14) An open trial of piroxicam, a new nonsteroidal anti-inflammatory agent with long-lasting analgesic and antipyretic activities, was carried out on 49 children as outpatients with viral rhinopharyngitis.
(15) Three studies that describe antipyretic bioassay are detailed.
(16) The second place was held by antipyretics, most frequently Acylpyrin, during the summer months--20.4%.
(17) The antiinflammatory activity of the novel pyrrolidin-2-one derivative N-methoxy-3-(3,5-di-tert-butyl-4-hydroxybenzylidene)pyrrolidin-2-o ne (E-5110) was investigated and compared with those of indomethacin and piroxicam in various antiinflammatory, analgesic and antipyretic animal models.
(18) By these criteria, meclofenamic acid is a highly potent, acceptably safe and exceptionally well tolerated anti-inflammatory-antipyretic agent in rats when compared with other such drugs.
(19) These findings suggest that ibuprofen is a good alternative to paracetamol as an antipyretic.
(20) Acetaminophen is an effective mild analgesic and antipyretic agent.
Pharmaceutical
Definition:
(a.) Of or pertaining to the knowledge or art of pharmacy, or to the art of preparing medicines according to the rules or formulas of pharmacy; as, pharmaceutical preparations.
Example Sentences:
(1) Senator Bernie Sanders of Vermont, who is also seeking the Democratic presidential nomination, recently proposed a bill that would ease the financial burden of prescription drugs on elderly Americans by allowing Medicare, the national social health insurance program, to negotiate with the pharmaceutical companies to keep prices down.
(2) Pharmaceutical services were provided from a large tent near the hospital, which consisted of an emergency treatment facility, two operating rooms, and a small medical-surgical ward.
(3) An investigation was done on the action in vitro of two pharmaceutical preparations containing Bi, De Nol and Pepto Bismol, on the fermentative capacity of intestinal bacteria.
(4) The conference was held from December 3 to 5, 1990 in the Washington, DC area and was sponsored by the American Association of Pharmaceutical Scientists, US Food and Drug Administration, Federation International Pharmaceutique, Health Protection Branch (Canada) and Association of Official Analytical Chemists.
(5) Silufol plates can be used for the control of the production of vitamins, their analysis in varying biological objects, as well as in biochemistry, medicine and pharmaceutics.
(6) Variations in bioavailability and intestinal absorption are important factors in the determination of dosage and should be reduced to a minimum by improved pharmaceutical formulations.
(7) This new derivative could represent a desirable complementation to rhbFGF for the development of more stable pharmaceutical formulations in wound healing applications.
(8) A report of the meeting will be published tomorrow in the Pharmaceutical Journal.
(9) There was no statistically significant difference between the figures obtained by the 2 methods, except for pharmaceutical expenditures (P = 0.005) which were grossly underevaluated by the program.
(10) Pharmaceutical services in a medical screening clinic are described.
(11) Slow release lithium was found a reliable pharmaceutical tool in both providing therapeutic results and avoiding severe side-effects.
(12) The efficacy and tolerability of a new pharmaceutical formulation of a non-steroid anti-inflammatory drug, nimesulide were studied in a double blind study in comparison with flurbiprofen and diclofenac sodium, in 150 patients suffering from postsurgical pain-inflammatory symptoms.
(13) A health committee meeting in Sacramento, the state capital, on Wednesday turned into a tense showdown between lawmakers seeking to argue that the science is unequivocally on the side of universal vaccination, and activists accusing them of being in the pocket of unscrupulous big pharmaceutical companies.
(14) Clarithromycin (TE-031, A-56268) is a new 14-membered ring macrolide antibiotic developed by Taisho Pharmaceutical Co., Ltd. TE-031 has a methoxy group at position 6 in its structure.
(15) This is especially relevant in light of the use of laboratory mammals to predict the metabolism of novel pharmaceutical agents in humans.
(16) The Double Irish loophole allows US companies, mostly in the technology and pharmaceutical sectors, to reduce their effective tax bill far below Ireland’s already generous 12.5% corporate tax rate by shifting most of their taxable income from an operating company in Ireland to another Irish-registered firm located in an offshore tax haven, such as Bermuda.
(17) Propylene glycol (PG) is widely used as a drug solvent in the pharmaceutical industry.
(18) The experimental drug, known as GSK2606414, is made by pharmaceutical company GlaxoSmithKline.
(19) The Office for National Statistics reported a drop in output across the manufacturing sector, from pharmaceutical firm to makers of computers, electronic & optical products; and food products, beverages & tobacco goods.
(20) The second approach for a UK-listed drug company by a US rival underlined the deal-making zeal that has seized the pharmaceutical sector.