(n.) A medicine which prevents or allays spasms or convulsions.
Example Sentences:
(1) The results show that both drugs possess sedative, antispasmodic, antipyretic, antiinflammatory, cardiotonic and hypotensive effects, the strength of effect and toxicity being similar.
(2) Parameters associated with the separation of antianxiety-antispasmodic agents were investigated using high-pressure liquid chromatography.
(3) Himachalol has been identified as the major antispasmodic constituent in the wood of Cedrus deodara.
(4) Based on these observations, tiropramide was considered to be at least as effective an antispasmodic as octilonium and at least as effective a synchronizer as trimebutine, but was different from both reference drugs because it was the only one to act simultanously as both an antispasmodic and a synchronizer.
(5) Anticholinergic or combined anticholinergic, antispasmodic, and local anesthetic treatment resolved the clinical signs in all 3 animals.
(6) As a continuation of our goals to study molecular probes for muscarinic cholinergic receptors, a series of 3-substituted 2-methyl-2-phenylpropanoates with the general structure of C6H5C(CH2X)(CH3)COOCH2CH2NEt2 where X = OH, OTs, F, Cl, Br, I, and OAc were prepared and their antispasmodic activities examined on isolated rat ileum preparations.
(7) Of the patients, 40% were treated surgically, and 69% received some form of medical treatment, including antispasmodics, estrogen, Kegel's exercises, urethral dilatation and bladder drills; 9% were given a trial of medical therapy followed by surgical therapy.
(8) In this factory, two kinds of anti-inflammatory enzyme (bromelain and trypsin), one anti-inflammatory agent (flufenamic acid), one antispasmodic (flopropion) and two kinds of antibiotics (ampicillin and cephalexin) are mainly produced.
(9) Influence of the Na removal from bath solution on the antispasmodic actions of isoproterenol and papaverine against the phasic contractions by K and acetylcholine were investigated in relation to the mobilization of Ca in isolated rectal strip from the rat.
(10) Nicorandil was thus considered to produce its antianginal effect primarily by redistribution of coronary blood flow as a result of dilatation of vascular beds and by its antispasmodic action.
(11) Atropine and two other widely employed antispasmodics (i.e., rociverine and octylonium bromide) were employed as reference compounds.
(12) The study was designed to elicit any interference on the part of dipyrone with the antispasmodic activity of 2-(diethylamino)-1-methylethyl cis-1-hydroxy(bicyclohexyl)-2-carboxylate (rociverine) and on the part of rociverine with the analgesic activity of dipyrone.
(13) The following assumption was obtained on the antispasmodic action of Cd and Mn, on the basis of the influence of Ca removed from bath solution and of addition of high K to bath solution and the analysis with concentration-action curves.
(14) After decreasing the uterine contractions by intravenous isossuprine, sixty patients were subsequently treated with magnesium Oxide, fifty with oral isossisuprine, twenty with a simple antispasmodic and the remaining constituted the control group.
(15) An analysis was made of the prognosis over a one-year follow-up period of a consecutive series of 86 out patients with irritable bowel syndrome (SII) who were treated randomly with an antispasmodic (otilonium) or a tranquilizer (clobazam), and the existence of factors, mainly psychological, that could worsen it was determined with the Zung anxiety test and the Hamilton depression scale.
(16) Reassurance, tranquillizers and antispasmodics help patients with functional dyspepsia.
(17) To postprandial pain antispasmodics or trimebutine are most effective when prescribed before meal.
(18) Antispasmodic operation designed by the authors was performed on them.
(19) These labile ischaemic changes indicate that prior to complete occlusion the vessel may be in a dynamic state when antispasmodic and antithrombotic therapies may be of value.
(20) All the three preparations suppressed the motor activity, decreased the muscle tone and the body temperature, potentiated the action of hexenal, possessed the antispasmodic and hypnotic activity.
Antispastic
Definition:
(a.) Believed to cause a revulsion of fluids or of humors from one part to another.
(a.) Counteracting spasms; antispasmodic.
(n.) An antispastic agent.
Example Sentences:
(1) These data are evidence of a specific glycinergic interaction with putative antispastic agents and can explain some conflicting effects of memantine in experimentally induced seizures.
(2) The three patients have been observed for more than 1 year, during which time the antispastic activity of intrathecally infused baclofen has remained stable.
(3) After stressing the uncertainties of classifying the syndrome exactly and the part played by psychosomatism in its aetiopathogenesis, some forms of acupuncture have been attempted as alternatives to psychodrugs and antispastic substances.
(4) The results support the role of cyproheptadine as an antispastic medication.
(5) In 7 patients MI developed when antispastic agents were not used and in 2, when angina persisted even under treatment with calcium antagonist.
(6) The symptoms developed by the chemical destruction of the interneurones of the spinal cord, with rigidity and spasticity of the hind limbs, are suitable for testing antispastic drugs.
(7) The effectiveness of an antispasticity drug may be too subtle to be perceived subjectively and objectively.
(8) In about one third of patients with violent spasticity due to spinal trauma, multiple sclerosis, and diffuse brain injury adequate control with oral antispastic medication cannot be achieved and successful rehabilitation is severely handicapped.
(9) These results indicate that eperisone possesses the property of a Ca antagonist on smooth muscle tissues of the guinea-pig basilar artery, in addition to the action of antispastic agent, i.e., this agent blocks the voltage-dependent influx of Ca at the smooth muscle membrane, but not at the nerve terminals, and inhibits the action of Ca in cells through inhibition of the contractile protein.
(10) The present study underscores that neither baclofen nor tizanidine are ideal antispastic drugs, and emphasize the need for further research.
(11) The literatures of two antispastic drugs, baclofen and dantrolene sodium, were studied bibliometrically for their first decade and were found to be generally similar.
(12) Spasticity greatly interfered with their activity in daily life and was resistant to oral antispastic medications.
(13) We have studied the effect of isometheptene, an indirectly acting sympathomimetic with analgesic and antispastic properties, on secretin-cholecystokinin-stimulated pancreatic and biliary outputs.
(14) Although there were no statistically significant differences between the two drugs, the global assessment of antispastic efficacy revealed a nearly significant difference (p = 0.057) in favour of tizanidine and the global assessment of tolerability was also in favour of tizanidine.
(15) Intrathecal administration of antispastic medications allows high concentrations of drug near the site of action, which limits side effects.
(16) However, antispastic drugs are usually ineffective.
(17) A double-blind placebo trial was taken with Lioresal, and antispasticity drug acting on the spinal cord level.
(18) A genetically determined syndrome of spasticity in the rat permits the quantitative evaluation of the antispastic effects of drugs by recording activity in the electromyogram (EMG) from a hind limb extensor muscle.
(19) The antispastic efficacy of tizanidine was greater after 8 weeks than after 2 weeks, whereas the efficacy of baclofen decreased slightly with time.
(20) A double-blind placebo trial was taken with Lioresal, an antispasticity drug acting on the spinal cord level.