(n.) Concern or solicitude respecting some thing or event, future or uncertain, which disturbs the mind, and keeps it in a state of painful uneasiness.
(n.) Eager desire.
(n.) A state of restlessness and agitation, often with general indisposition and a distressing sense of oppression at the epigastrium.
Example Sentences:
(1) During and after the infusion of 5HTP, none of the patients showed an increase in anxiety or depressive symptoms, despite the presence of severe side effects.
(2) Several interpretations of the results are examined including the possibility that the effects of Valium use were short-lived rather than long-term and that Valium may have been taken in anticipation of anxiety rather than after its occurrence.
(3) However, it is easier for them to cope with anxiety because premedication pacifies the patients, whereas each of the dependent variables, such as apprehension, is influenced differently.
(4) Anxious mood and other symptoms of anxiety were commonly seen in patients with chronic low back pain.
(5) Lactate-induced anxiety and symptom attacks without panic were seen more often in the groups with panic attacks, but a full-blown panic attack was provoked in only four subjects, all belonging to the groups with a history of panic attacks.
(6) Higher anxiety, depression and psychiatric morbidity scores were reported by all patients at 6 and, to a lesser extent, at 12 weeks with greater differences in women.
(7) Anxiety conditions were measured by monitoring palmar skin resistance with a psychogalvanometer.
(8) Ex-patients of a dental fear clinic were found to have significantly reduced, yet still high, dental anxiety scores in comparison with the pre-intervention scores.
(9) However, a decision-sharing approach had a significant effect on reducing anxiety levels in third-grade children.
(10) Forty five elderly patients undergoing total hip replacements were assessed one day before and two days after surgery in order to explore the relationship between pre-operative anxiety and post-operative delirium.
(11) Seventy-three percent of 90 psychiatric inpatients had a coexisting anxiety disorder.
(12) Although the general guiding principle of pharmacotherapy for anxiety disorders--the lowest effective dose for the shortest possible time--remains, this rule should not interfere with the judicious use of medications as long as the benefits justify it.
(13) Ketazolam was found to be significantly better than placebo in alleviating anxiety and its concomitant symptomatology as measured by the Hamilton Anxiety Rating Scale, three Physician's Global Impressions, two Patient's Global Impressions, and three Target Symptoms.
(14) The following examinations could be proposed: in high risk cases determined before pregnancy, a chorionic villus sampling should be done between the 9th and 11th weeks of gestation; in low risk cases such as advanced maternal age, a first trimester chorionic villus sampling or a second trimester amniocentesis could be chosen; in the case of Down's syndrome, warning signs, for example ultrasonographic or biological parameters, a second trimester placental biopsy to relieve the parents' anxiety; in high risk cases such as ultrasonographic malformations, late placental biopsy or cordocentesis.
(15) Subjective measures of anxiety, frightening cognitions and body sensations were obtained across the phases.
(16) The focus will be on assessment of the gravid woman's anxiety levels and coping skills.
(17) Anxiety, depression, and somatization were greater in RAP mothers than well mothers.
(18) The writer Palesa Morudu told me that she sees, in the South African pride that "we did it", a troubling anxiety that we can't: "Why are we celebrating that we built stadiums on time?
(19) The encouraging pilot results warrant a controlled study of exposure for dysmorphophobic avoidance and anxiety.
(20) Study of the clinical characteristics of depressive state by hemisphere stroke with the use of symptom items of Zung scale and Hamilton scale showed that patients in depressive state with right hemisphere stroke had high values in symptom items considered close to the essence of endogenous depression such as depressed mood, suicide, diurnal variation, loss of weight, and paranoid symptoms, while patients in depressive state with left hemisphere stroke had high values in symptom items having a nuance of so-called neurotic depression such as psychic anxiety, hypochondriasis, and fatigue.
Anxiolytic
Definition:
Example Sentences:
(1) Open field behaviors and isolation-induced aggression were reduced by anxiolytics, at doses which may be within the sedative-hypnotic range.
(2) It is concluded that in the mouse model the ability of buspirone to reduce the aversive response to a brightly illuminated area may reflect an anxiolytic action, that the dorsal raphe nucleus may be an important locus of action, and that the effects of buspirone may reflect an interaction at 5-hydroxytryptamine receptors.
(3) 3 alpha-hydroxylated pregnane steroids have been shown to possess anesthetic, hypnotic, anticonvulsant and anxiolytic properties.
(4) Pharmacokinetic studies revealed that the hydrophilic pyridinium salt form (G-Q+) of the GABA-CDS formed in situ remained in the brain for 12 h but was cleared from the blood and other peripheral tissues by 0.5-4 h. While the lipophilic form (G-DH) of the GABA-CDS caused a marked and sustained anxiolytic response when administered systemically, GABA and the charged pyridinium salt (G-Q+ form) of the GABA-CDS were ineffective.
(5) The novel anxiolytic drug, buspirone, reverses catalepsy induced by haloperidol.
(6) The anxiolytic activity of serotonin agonists (buspirone, ipsapirone, campirone, caplapirone, 1-pyrimidinyl-piperazine) determined in rats on 3 experimental models of anxiety closely correlates with the degree of inhibition of impulse release of 3H-serotonin by electrically stimulated slices of the midbrain raphe dorsal nucleus (r = +0.85) but not the slices of the cerebral hemispheric cortex (r = +0.60) of the rats.
(7) Buspirone, an azapirone derivative and a 5-HT1A partial agonist, is the first nonbenzodiazepine anxiolytic introduced into medicine for the treatment of generalized anxiety disorder.
(8) In general, tolerance has not been found to anxiolytic effects after 7-15 days of treatment, although in the social interaction test it was found after 25 days.
(9) However, antidepressants may enhance the efficiency of responding on DRL schedules whereas anxiolytics tend to disrupt such behavior.
(10) With benzodiazepines, StD of memory retrieval conceivably constitutes a parsimonious explanation of the anxiolytic and untoward (amnesic, drug dependence) actions of these drugs.
(11) Benzodiazepines are highly effective and safe anxiolytics, but with continuous use these agents have demonstrated psychologic and physical dependence problems.
(12) Putative blockers of the GABA-receptor coupled chloride channel, picrotoxin and pentylenetetrazol, and the benzodiazepine receptor antagonists Ro 15-1788 and CGS 8216 each blocked the anxiolytic effect of chlordiazepoxide.
(13) These attenuating effects may be related to the anxiolytic action of barbiturates.
(14) Calls are also sensitive to a variety of purported anxiolytic and anxiogenic drugs, including the benzodiazepines, serotonin agonists, and ligands at the NMDA-glycine receptor complex.
(15) The agonist beta-carboline derivative ZK 93423, the anxiolytic cyclopyrrolones suriclone and zopiclone and the purines inosine and hypoxanthine all failed to inhibit antibody binding, supporting previous suggestions that these drugs may bind at non-benzodiazepine recognition sites on the CNS receptor.
(16) The behavioral effects of several new anxiolytics and putative anxiolytics were evaluated in two tests sensitive for anxiolytic activity.
(17) Pooled data for 427 patients with generalized anxiety disorders were analyzed retrospectively from six double-blind trials evaluating buspirone, a nonbenzodiazepine anxiolytic, in the treatment of generalized anxiety disorder.
(18) The nature of the effects favours an 'anxiolytic' hypothesis of melatonin action rather than the other hypotheses so far proposed.
(19) A good agreement was established between the anxiolytic (tranquilizing) effect of phenazepam after administration to rats per os and the rate of its supply to the systemic blood flow.
(20) The literature on the effects of anxiolytic and hypnotic drugs on performance in tasks requiring sustained attention is confusing.