(1) In recent studies, we have found that Gal alpha 1----3Gal beta 1----4GlcNAc residues are abundant on red cells and nucleated cells of nonprimate mammals, prosimians, and New World monkeys, but their expression is diminished in Old World monkeys, apes, and humans.
(2) The sequence of the murine protein differs from that of the human protein in 10% of residues, and it may be presumed that some of these differences are responsible for the inability of gibbon ape leukemia virus to infect mouse fibroblasts.
(3) Other differences in cytoarchitecture, within the great apes and humans, include decreases in the small and giant cell populations of the cochlear complex.
(4) In order to analyse possible mechanisms of N-action of these factors, we have cultured APE explants for 3 or 18 h in the medium containing various concentrations of con A, PHA of EBDNF.
(5) We are by far the most successful of the great apes and have pushed our cousins right up against the wall.
(6) Finally, the M. fuscata replication sequence presented here will provide a necessary foundation for future comparisons between apes and man.
(7) Miocene hominoids from Europe are among the earliest members of the great ape and human clade (the Hominidae).
(8) 4-[[N-(3-Chlorophenyl)-carbamoyl]oxy]-2-butynyltrimethylammonium chloride (McN-A-343) and N-ethyl-guvacine propargyl ester (NEN-APE) produced minimal or no arteriolar vasodilation.
(9) Gibbons that acquired infectious gibbon ape leukemia virus, either naturally by exposure to a virus-shedding ape or experimentally by deliberate virus inoculation, had the same levels of serum lytic activity as did unexposed gibbons that had no detectable antibodies to gibbon ape leukemia virus.
(10) After this separation, the ancestral DRB1 gene of the DRw52 group duplicated in the Old World monkey lineage to give rise to genes at three loci at least, while in the ape lineage this gene may have remained single and diverged into a number of alleles instead.
(11) The results conform to the general pattern that great apes exhibit many cognitive skills comparable to those of 2-year-old humans.
(12) They adhered to and, when capacitated, penetrated the vestments of the oocyte of an ape--the gibbon, Hylobates lar--both in vivo and in vitro.
(13) Relative to human, no translocations were detected in great apes, except for the well-known fusion-origin of human chromosome 2 and a 5;17 translocation in the gorilla.
(14) Replacement of the N-methyl group in arecoline and APE by larger substituents (ethyl, n-propyl, n-butyl, benzyl, phenylethyl) as well as N-methylation resulted in a decrease or even a complete loss of agonistic activity.
(15) The deflecting wrinkle is a well-known character state of the lower m2 and M1 of the human dentition, but there is little information regarding its presence in great apes.
(16) She had no idea what she was saying.” The girl, Julia, was escorted from the ground by security guards after she was identified by Goodes as having called him an “ape” .
(17) Gonococci attached to, damaged, and invaded the oviduct (fallopian tube) mucosa of chimpanzees (which are apes) but not the oviduct mucosa of baboons (which are monkeys).
(18) The TLC analysis indicated that the oligomer produced by APE is not identical to the 2'-5' oligoadenylate.
(19) All positive sera from gibbon apes reacted as HSV-1 positive.
(20) Little evidence exists that apes can use symbols as names, that is, as a means of simply transmitting information.
Apod
Definition:
(n.) Alt. of Apodal
(n.) Alt. of Apode
Example Sentences:
(1) The findings of both apoD and LCAT synthesis in the brain suggest that they play a significant role in lipid transport in the brain.
(2) ApoD, isolated by a procedure combining hydroxylapatite and Sephadex G-100 column chromatography, migrated on 7% polyacrylamide gel as a single band with a mobility intermediate between those of A-II and C-II polypeptides.
(3) However, immunocytochemical localization of apoD in 12 tissues (liver, kidney, bladder, adrenal, cerebrum, duodenum, testis, lung, spleen, pancreas, heart, and skin) showed that a variety of cells contained substantial levels of apolipoprotein.
(4) Carbohydrate analysis demonstrated that ApoD is a glycoprotein with glucose, mannose, galactose, glucosamine, and sialic acid accounting for 18% of the dry weight of ApoD.
(5) The role of ApoD in the plasma lipoprotein system remains to be discovered, but the recent, rapid increase in our knowledge of this protein suggests that it plays an important role in the homeostasis or housekeeping of probably all organs.
(6) The importance of the Stiles-Crawford apodization depends on the wave aberration of the individual subject, but in general it produces an improvement in image quality, and the modulation transfer function becomes more symmetrical.
(7) The relationship between the ultrasound beam and the observed signal spectrum has been investigated by employing a computer-based model of the ultrasound field which enabled the calculation of: 1, pressure (amplitude and phase angle) field distributions from plane disc and focused transducers with unapodized and apodized aperture field distributions; 2, the Doppler signal from a scatterer moving through the field; and 3, the spectrum of this signal.
(8) When injected into rabbits it produced antisera that reacted only with ApoD.
(9) It is concluded that a fraction of human apoD, like other cysteine-containing apolipoproteins, exists as a disulfide-linked heterodimer with other apolipoproteins in all major human lipoprotein fractions.
(10) Thus, our results show that the apoD gene is expressed mainly in peripheral organs, with levels as high as 59-fold that of the liver, unlike other apolipoproteins.
(11) This report describes further studies on the characterization of apolipoprotein D (ApoD), a recently recognized human plasma apolipoprotein, and presents results on the isolation and distribution of its lipoprotein form, lipoprotein D (LP-D).
(12) In this report we have identified the apolipoprotein by partial amino acid sequence analysis as apolipoprotein (apo) D. Characterization of rat apoD by sodium dodecyl sulfate-polyacrylamide gel electrophoresis showed it to be composed of a series of molecular weight isoforms of between 27 kDa and 31 kDa that increase 2 kDa in apparent molecular mass upon reduction.
(13) The chemical structure of the natural ligand, or ligands, of ApoD in normal cells in vivo or in culture is not known, but ApoD has been shown to bind some steroids and bilirubin.
(14) Results showed that patients with GSD-I have a unique apolipoprotein profile characterized by normal or slightly decreased levels of ApoA-I and ApoA-II, reduced concentrations of ApoD, and significantly increased levels of ApoC-I and ApoC-II (p less than 0.01) and ApoB, ApoC-III, and ApoE (p less than 0.0001) in comparison with age- and sex-matched normolipidemic controls.
(15) All plasmas tested contained apoD and an Mr 38,000 antigen, the latter being the most immunoreactive.
(16) The reactions of antibodies to apoA-I, apoA-II, apoE, apoB, apoD, and apoA-IV have revealed discrete bands of particles which differ widely in size and apolipoprotein composition.
(17) The structure of ApoD and its sites of synthesis have been discovered.
(18) Specifically, apoD mRNA was abundant near blood vessels and was expressed mostly in fibroblast-like cells, in particular in the testis, the efferent ducts, the ductus epididymis, the lung, and the subarachnoid space of the CNS.
(19) This high degree of similarity shows that the rabbit system can be used as a model for apoD studies.
(20) In this report, we have identified two apolipoproteins (apo), apoD and apoA-IV, that, together with the previously identified apoA-I and apoE, accumulate in the regenerating peripheral nerve.