(1) The findings of both apoD and LCAT synthesis in the brain suggest that they play a significant role in lipid transport in the brain.
(2) ApoD, isolated by a procedure combining hydroxylapatite and Sephadex G-100 column chromatography, migrated on 7% polyacrylamide gel as a single band with a mobility intermediate between those of A-II and C-II polypeptides.
(3) However, immunocytochemical localization of apoD in 12 tissues (liver, kidney, bladder, adrenal, cerebrum, duodenum, testis, lung, spleen, pancreas, heart, and skin) showed that a variety of cells contained substantial levels of apolipoprotein.
(4) Carbohydrate analysis demonstrated that ApoD is a glycoprotein with glucose, mannose, galactose, glucosamine, and sialic acid accounting for 18% of the dry weight of ApoD.
(5) The role of ApoD in the plasma lipoprotein system remains to be discovered, but the recent, rapid increase in our knowledge of this protein suggests that it plays an important role in the homeostasis or housekeeping of probably all organs.
(6) The importance of the Stiles-Crawford apodization depends on the wave aberration of the individual subject, but in general it produces an improvement in image quality, and the modulation transfer function becomes more symmetrical.
(7) The relationship between the ultrasound beam and the observed signal spectrum has been investigated by employing a computer-based model of the ultrasound field which enabled the calculation of: 1, pressure (amplitude and phase angle) field distributions from plane disc and focused transducers with unapodized and apodized aperture field distributions; 2, the Doppler signal from a scatterer moving through the field; and 3, the spectrum of this signal.
(8) When injected into rabbits it produced antisera that reacted only with ApoD.
(9) It is concluded that a fraction of human apoD, like other cysteine-containing apolipoproteins, exists as a disulfide-linked heterodimer with other apolipoproteins in all major human lipoprotein fractions.
(10) Thus, our results show that the apoD gene is expressed mainly in peripheral organs, with levels as high as 59-fold that of the liver, unlike other apolipoproteins.
(11) This report describes further studies on the characterization of apolipoprotein D (ApoD), a recently recognized human plasma apolipoprotein, and presents results on the isolation and distribution of its lipoprotein form, lipoprotein D (LP-D).
(12) In this report we have identified the apolipoprotein by partial amino acid sequence analysis as apolipoprotein (apo) D. Characterization of rat apoD by sodium dodecyl sulfate-polyacrylamide gel electrophoresis showed it to be composed of a series of molecular weight isoforms of between 27 kDa and 31 kDa that increase 2 kDa in apparent molecular mass upon reduction.
(13) The chemical structure of the natural ligand, or ligands, of ApoD in normal cells in vivo or in culture is not known, but ApoD has been shown to bind some steroids and bilirubin.
(14) Results showed that patients with GSD-I have a unique apolipoprotein profile characterized by normal or slightly decreased levels of ApoA-I and ApoA-II, reduced concentrations of ApoD, and significantly increased levels of ApoC-I and ApoC-II (p less than 0.01) and ApoB, ApoC-III, and ApoE (p less than 0.0001) in comparison with age- and sex-matched normolipidemic controls.
(15) All plasmas tested contained apoD and an Mr 38,000 antigen, the latter being the most immunoreactive.
(16) The reactions of antibodies to apoA-I, apoA-II, apoE, apoB, apoD, and apoA-IV have revealed discrete bands of particles which differ widely in size and apolipoprotein composition.
(17) The structure of ApoD and its sites of synthesis have been discovered.
(18) Specifically, apoD mRNA was abundant near blood vessels and was expressed mostly in fibroblast-like cells, in particular in the testis, the efferent ducts, the ductus epididymis, the lung, and the subarachnoid space of the CNS.
(19) This high degree of similarity shows that the rabbit system can be used as a model for apoD studies.
(20) In this report, we have identified two apolipoproteins (apo), apoD and apoA-IV, that, together with the previously identified apoA-I and apoE, accumulate in the regenerating peripheral nerve.
Pod
Definition:
(n.) A bag; a pouch.
(n.) A capsule of plant, especially a legume; a dry dehiscent fruit. See Illust. of Angiospermous.
(n.) A considerable number of animals closely clustered together; -- said of seals.
(v. i.) To swell; to fill; also, to produce pods.
Example Sentences:
(1) Middle component particles of bean pod mottle virus (BPMV) containing small protein subunits with a cleaved C terminus were used to produce monoclonal antibodies (MAbs).
(2) The length of small intestine, large intestine and caeca and the weight of gizzard expressed per kg of body weight increased with an increase in the level of carob pods meal, which is rich in fibre, in the diets.
(3) The other group of patients (n = 52) received CsA from the first POD, together with AZA and steroids.
(4) The anastomotic index was similar on postoperative day (POD) 1, 4, and 7; but on day 28 all handsewn anastomoses had larger diameters than the widest CEEA anastomosis.
(5) Sleep in the grand house (B&B doubles from £90) or in a yurt, eco-pod or your own tent.
(6) The trypsin inhibitor of Phaseolus vulgaris L. pods is thermosensitive but stable at low pH.
(7) The peroxidase-(POD)-thiocyanate-hydrogenperoxide-system is a well-known antibacterial system, which has been demonstrated to exist, for example, in milk and saliva.
(8) The other drowned patient (53 years) died on the 3rd postoperative day (POD) from ARDS.
(9) One farmer in Hebei province built seven buoyant steel-and-fibreglass "survival pods" in his garage.
(10) All control animals showed destructive grade 4 changes by POD 7.
(11) For the custard 4 egg yolks 400ml double cream 60g caster sugar 1 tbsp cornflour 1 tsp vanilla essence (or ½ vanilla pod, split) 1 Whisk the egg yolks for a minute in a largish heat-proof bowl (you need to be able to whisk the hot cream in later without worrying about it spilling over.)
(12) Long respiratory care was continued after tracheotomy, and finally he could wean from the mechanical respiratory care utilizing acetazolamide (carbonic anhydrase inhibitor) on 59 POD.
(13) Dimethylsulfoxide (15%) does not alter the LMG conversion rate of free POD, whilst a rate loss by 60% was observed for the immobilized enzyme.
(14) All patients with unfavourable neurological outcome were considered POD if absolute or relative contraindications to organ procurement were absent.
(15) We report here on a paternity analysis, using DNA fingerprinting, of mother-fetus pairs and males sampled from complete pods.
(16) I've just been in the pod listening to Sid Lowe talking about the possible Real Madrid players that Arsenal may be able to shake out of the Bernabéu in a Gareth Bale deal.
(17) In normal livers, only occasional sinusoid-lining cells were stained, whereas in SHN following POD or presumed viral hepatitis, hepatocytes of variable morphology showed significant immunoreactivity.
(18) Yang told the South China Morning Post that his biggest customers are businessmen from coal-rich Shanxi province; they have decided to remain anonymous for fear that panicked neighbors will try to steal their pods.
(19) At 53 days POD, lymphoblastic neoplastic cells in the dermis reacted with anti-T lymphocyte monoclonal antibody by the avidin biotin peroxidase complex method.
(20) The POD-like behavior of different DMEP esters indicates that specific attachment of the R group to the C-4 glucoside moiety is required for VM26-like activity.