(1) The findings of both apoD and LCAT synthesis in the brain suggest that they play a significant role in lipid transport in the brain.
(2) ApoD, isolated by a procedure combining hydroxylapatite and Sephadex G-100 column chromatography, migrated on 7% polyacrylamide gel as a single band with a mobility intermediate between those of A-II and C-II polypeptides.
(3) However, immunocytochemical localization of apoD in 12 tissues (liver, kidney, bladder, adrenal, cerebrum, duodenum, testis, lung, spleen, pancreas, heart, and skin) showed that a variety of cells contained substantial levels of apolipoprotein.
(4) Carbohydrate analysis demonstrated that ApoD is a glycoprotein with glucose, mannose, galactose, glucosamine, and sialic acid accounting for 18% of the dry weight of ApoD.
(5) The role of ApoD in the plasma lipoprotein system remains to be discovered, but the recent, rapid increase in our knowledge of this protein suggests that it plays an important role in the homeostasis or housekeeping of probably all organs.
(6) The importance of the Stiles-Crawford apodization depends on the wave aberration of the individual subject, but in general it produces an improvement in image quality, and the modulation transfer function becomes more symmetrical.
(7) The relationship between the ultrasound beam and the observed signal spectrum has been investigated by employing a computer-based model of the ultrasound field which enabled the calculation of: 1, pressure (amplitude and phase angle) field distributions from plane disc and focused transducers with unapodized and apodized aperture field distributions; 2, the Doppler signal from a scatterer moving through the field; and 3, the spectrum of this signal.
(8) When injected into rabbits it produced antisera that reacted only with ApoD.
(9) It is concluded that a fraction of human apoD, like other cysteine-containing apolipoproteins, exists as a disulfide-linked heterodimer with other apolipoproteins in all major human lipoprotein fractions.
(10) Thus, our results show that the apoD gene is expressed mainly in peripheral organs, with levels as high as 59-fold that of the liver, unlike other apolipoproteins.
(11) This report describes further studies on the characterization of apolipoprotein D (ApoD), a recently recognized human plasma apolipoprotein, and presents results on the isolation and distribution of its lipoprotein form, lipoprotein D (LP-D).
(12) In this report we have identified the apolipoprotein by partial amino acid sequence analysis as apolipoprotein (apo) D. Characterization of rat apoD by sodium dodecyl sulfate-polyacrylamide gel electrophoresis showed it to be composed of a series of molecular weight isoforms of between 27 kDa and 31 kDa that increase 2 kDa in apparent molecular mass upon reduction.
(13) The chemical structure of the natural ligand, or ligands, of ApoD in normal cells in vivo or in culture is not known, but ApoD has been shown to bind some steroids and bilirubin.
(14) Results showed that patients with GSD-I have a unique apolipoprotein profile characterized by normal or slightly decreased levels of ApoA-I and ApoA-II, reduced concentrations of ApoD, and significantly increased levels of ApoC-I and ApoC-II (p less than 0.01) and ApoB, ApoC-III, and ApoE (p less than 0.0001) in comparison with age- and sex-matched normolipidemic controls.
(15) All plasmas tested contained apoD and an Mr 38,000 antigen, the latter being the most immunoreactive.
(16) The reactions of antibodies to apoA-I, apoA-II, apoE, apoB, apoD, and apoA-IV have revealed discrete bands of particles which differ widely in size and apolipoprotein composition.
(17) The structure of ApoD and its sites of synthesis have been discovered.
(18) Specifically, apoD mRNA was abundant near blood vessels and was expressed mostly in fibroblast-like cells, in particular in the testis, the efferent ducts, the ductus epididymis, the lung, and the subarachnoid space of the CNS.
(19) This high degree of similarity shows that the rabbit system can be used as a model for apoD studies.
(20) In this report, we have identified two apolipoproteins (apo), apoD and apoA-IV, that, together with the previously identified apoA-I and apoE, accumulate in the regenerating peripheral nerve.
Feet
Definition:
(n. pl.) See Foot.
(n.) Fact; performance.
(pl. ) of Foot
Example Sentences:
(1) 7 right-handed male university students stood behind a large Plexiglas screen and spatially matched a ball projected over a distance of 20 feet.
(2) The Vatican spokesman said two of the 12 whose feet were washed were Muslim inmates.
(3) The present study includes six patients, (involving ten feet), who developed hallux varus and great toe clawing after McBride procedures were performed by various orthopedic surgeons.
(4) Often they were 3-0 up by then, but that is unlikely to be the case in the World Cup , and in 30 degrees we could be out on our feet after 20 minutes.
(5) The area occupied by parenchymal cells, in sections comprising the entire half of the surface of the carotid body, is significantly greater in people born and living at 14,350 feet than in those at sea level.
(6) Deformities of the foot were common, and twelve feet had been operated on for correction.
(7) Nonmetallic foreign bodies were embedded in cadaver feet.
(8) I was so tired I just used to fall asleep on my feet.
(9) Callosities under at least one metatarsophalangeal joint were noted in fifty (69 per cent) of the feet that had a physical examination.
(10) Although the majority of pigs had lesions in feet, or had dyschondroplastic changes typical of osteochondrosis in many growth cartilages, particularly physes, there were no significant differences in frequency of pigs with lesions between groups.
(11) A matter of minutes after his appointment was announced on Thursday, the newly minted minister for Portsmouth was on his feet answering questions in the Commons.
(12) His balancing pole swayed uncontrollably, nearly tapping the sides of his feet.
(13) Cabin altitudes ranged from sea level to 8,915 feet (2717 m).
(14) The authors have presented a forensic anthropology case that established positive identification by comparison of antemortem and postmortem x-rays of the legs and feet.
(15) This is a team who have found their feet after that winless group section, a side who have already seen off the much admired Croatia and who can ruffle the feathers of the hosts or the reigning world champions.
(16) He was looking down at his feet - and she realised he felt the shame, too.
(17) The presence of flat feet and excessive laxity of the joints, associated with the characteristic facies, macro-orchidism, and behavior, justifies a referral for developmental and genetic evaluation.
(18) Fifteen feet had a good and two had a poor correction of the deformity of the hind part of the foot, the result being directly related to the intraoperative correction of the equinus deformity.
(19) The findings showed that flat feet are usual in infants, common in children, and within the normal range of the observations made in adult feet.
(20) A case is presented where the bones of both hands and both feet exhibited bone metastases.