(n.) A crystalline alkaloid obtained from morphia. It is a powerful emetic.
Example Sentences:
(1) Isolates showed a decrease in the intensity of apomorphine-induced stereotyped behaviours but no change in stereotypy induced by AMPH.
(2) The results show that centrally administered serotonin, the serotonin precursor, 5-hydroxytryptophan administered with clorgyline, a selective MAO A inhibitor, quipazine, a serotonin receptor agonist, and fluoxetine, a selective inhibitor of neuronal re-uptake of serotonin, attenuated all paradigms of FIA and apomorphine induced potentiation of FIA.
(3) When injected separately, in control experiments, both compounds had similar effects on the exploratory-motor activity and the emotional behaviour, but when injected simultaneously in various doses a distinct antagonism between l-DOPA and apomorphine, according to all the behaviour tests, was noted (a decrease of sterotypy, aggressiveness and emotional reactivity).
(4) The present experiment was conducted to determine if a single direct dopamine (DA) agonist, apomorphine (APO), pretreatment could produce a rapid uncoupling of the striatal DA D-2 receptor from its G-proteins.
(5) However, when mice pretreated with reserpine 24 h earlier were used, NPA was found to be 6.5 times more active in producing locomotor stimulation and 8.7 times more active in producing stereotypy than apomorphine.
(6) Metoclopramide did not counteract the apomorphine effect and, in higher doses, water intake was even further reduced.
(7) Morphine (0.1 to 5 micrograms), but not U-69,593 (5 micrograms), injected into the PVN 10 minutes before oxytocin or apomorphine, was found to be able to prevent penile erection and yawning induced by the unilateral PVN microinjection of oxytocin (10 ng) or apomorphine (50 ng).
(8) The relative bioavailability of SL apomorphine ranged from 10 to 22% of a parenteral apomorphine dose.
(9) Sleep induction has been studied in humans after the administration of apomorphine, a direct stimulant of the central dopaminergic system.
(10) Apomorphine (Apo), a short acting dopamine (DA) receptor agonist, stimulates growth hormone (GH) secretion, decreases prolactin secretion, induces yawning, penile erections and other physiological effects in man.
(11) of apomorphine or (-) N-n-propylnorapomorphine was increased significantly in the opiate-pretreated mice.
(12) Therefore, there is no evidence as yet that alterations in apomorphine-induced hypothermia after prenatal exposure to PhB indicates changes in DA receptors, and the implications of this phenomenon still remain an open question.
(13) Without shocks, apomorphine-treated rats displayed stereotypy with locomotion and biting of various objects.
(14) Upon administration of low doses of apomorphine and l-amphetamine, less dopamine- and norepinephrine-related behavior occurred with less magnesium in the diet.
(15) The opiate antagonist, naloxone, was used to determine whether endogenous opioids modulate behavioural effects induced by a low dose of apomorphine.
(16) The results suggest that apomorphine-induced gastric relaxation in the dog is mediated via a central site located in the region supplied by the vertebral artery, but that the gastric relaxatory effect of morphine is mediated by both a peripheral and a central site of action.
(17) Apomorphine-induced increase in rearing time was dose-dependently depressed by this antagonist.
(18) Apomorphine showed a high total plasma clearance (165-207 ml min-1 kg-1) and, despite a relatively large volume of distribution (3.4-4.1 litre kg-1), a biological half-life of about 14 min was obtained irrespective of route of administration.
(19) Apomorphine, a dopaminergic agonist was given over a period of 12 months to 14 parkinsonian patients suffering from severe L-dopa induced on-off effects.
(20) Rats with nigral or adrenal suspension grafts, but not rats with adrenal solid grafts, showed reduced apomorphine-induced rotation in comparison with lesion rats.
Treatment
Definition:
(n.) The act or manner of treating; management; manipulation; handling; usage; as, unkind treatment; medical treatment.
(n.) Entertainment; treat.
Example Sentences:
(1) Tryptic digestion of the membranes caused complete disappearance of the binding activity, but heat-treatment for 5 min at 70 degrees C caused only 40% loss of activity.
(2) Once treatment began, no significant changes occurred in Group 1, but both PRA and A2 rose significantly in Groups 2 and 3.
(3) Direct fetal digitalization led to a reduction in umbilical artery resistance, a decline in the abdominal circumference from 20.3 to 17.8 cm, and resolution of the ascites within 72 h. Despite this dramatic response to therapy, fetal death occurred on day 5 of treatment.
(4) In this study of ten consecutive patients sustaining molten metal injuries to the lower extremity who were treated with excision and grafting, treatment with compression Unna paste boot was compared with that with conventional dressing.
(5) The rash presented either as a pityriasis rosea-like picture which appeared about three to six months after the onset of treatment in patients taking low doses, or alternatively, as lichenoid plaques which appeared three to six months after commencement of medication in patients taking high doses.
(6) In conclusion, the efficacy of free tissue transfer in the treatment of osteomyelitis is geared mainly at enabling the surgeon to perform a wide radical debridement of infected and nonviable soft tissue and bone.
(7) Biochemical, immunocytochemical and histochemical methods were used to study the effect of chronic acetazolamide treatment on carbonic anhydrase (CA) isoenzymes in the rat kidney.
(8) Down and up regulation by peptides may be useful for treatment of cough and prevention of aspiration pneumonia.
(9) More than 2 months after the combined treatment were required for the suppression.
(10) Theoretical findings on sterilization and disinfection measures are useless for the dental practice if their efficiency is put into question due to insufficient consideration of the special conditions of dental treatment.
(11) The use of organophosphorus preparations in the treatment of ectoparasites and endoparasites of pigs is discussed.
(12) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
(13) With UVB treatment clinical improvement was achieved, and a less pronounced decrease in epidermal LC was noticed.
(14) Calcium alginate dressings have been used in the treatment of pressure ulcers and leg ulcers.
(15) The patients should have received treatment for at least seven days and they should not be "ill".
(16) Whether hen's egg yolk can be used as a sperm motility stimulant in the treatment of such conditions as asthenospermia and oligospermia is subjected for further study.
(17) Peripheral vascular surgery has become an increasingly common mode of treatment in non-university, community hospitals in Sweden during the last decade.
(18) We have investigated the increase in the spcDNA population upon cycloheximide treatment of individual sequences, which are found to amplify differentially.
(19) The purpose of these studies was to better understand the molecular basis of chromosome aberration formation after mitomycin C treatment.
(20) In all cases the polyarthritis is cured by anti-inflammatory treatment in 1-6 months.