(a.) Capable of being appreciated or estimated; large enough to be estimated; perceptible; as, an appreciable quantity.
Example Sentences:
(1) There was appreciable variation in toothbrush wear among subjects, some reducing their brush to a poor state in 2 weeks whereas with others the brush was rated as "good" after 10 weeks.
(2) Although solely nociresponsive neurons are clearly likely to fill a role in the processing and signalling of pain in the conscious central nervous system, the way in which such useful specificity could be conveyed by multireceptive neurons is difficult to appreciate.
(3) Once the normal variations are mastered, appreciation of retinal, choroidal, optic nerve, and vitreal abnormalities is possible.
(4) Grisham said she and other aides had not been aware of the trip and “appreciate everyone’s understanding”.
(5) The results suggest that involucrin-like proteins have a wider species distribution than originally appreciated.
(6) The independent but combined use of both antigens, appreciably raises the diagnostic success percentage with regard to that obtained when only one tumour marker was used.
(7) In assessing damaged nets and curtains it must be recognised that anything less than the best vector control may have no appreciable impact on holoendemic malaria.
(8) Furthermore, the AMDP-3 scale and its manual constitute a remarkable teaching instrument for psychopathology, not always enough appreciated.
(9) In retrospect, this parotid disease has similarity to the sonographic finding of Sjögren's syndrome, except for the finding of cervical adenopathy, an observation not previously appreciated.
(10) The rates of oxidation of various substrates and the acceptor control ratios did not differ appreciably between the two types of mitochondria.
(11) Faecal excretion of T3 declined appreciably relative to that of T4.
(12) During ischaemia M1 stretch responses showed a more rapid and pronounced decline than did M2 responses and were abolished before voluntary power was appreciably affected.
(13) No appreciable fusion of vesicles by apocytochrome c is observed.
(14) For Burroughs, who had been publishing ground-breaking books for 20 years without much appreciable financial return, it was association with fame and the music industry, as well as the possible benefits: a wider readership, film hook-ups and more money.
(15) and the turnover of (22)Na in this fluid it does not appreciably affect the turnover of (22)Na in the brain tissue of either rat or rabbit, the small inhibition observed being probably secondary to the effects on the c.s.f.3.
(16) PTH, an inducer of shape change, did not affect the number of gap junctions appreciably.
(17) He speeded the process of decolonisation, and was the first British prime minister to appreciate that Britain's future lay with Europe.
(18) Only the pyroglutamyl-AMC derivative was appreciably hydrolysed.
(19) Diminished pressor responsiveness was considered to be due to concurrent reduction of central sympathetic vasomotor activity, because sympathetic nerve responses to hypothalamic stimulation were appreciably lessened in tripamide-treated SHR.
(20) Gynaecological and neurological lesions are reaffirmed as important causes and pathology within the urinary tract is found to be a more frequent component that is usually appreciated.
Substantial
Definition:
(a.) Belonging to substance; actually existing; real; as, substantial life.
(a.) Not seeming or imaginary; not illusive; real; solid; true; veritable.
(a.) Corporeal; material; firm.
(a.) Having good substance; strong; stout; solid; firm; as, substantial cloth; a substantial fence or wall.
(a.) Possessed of goods or an estate; moderately wealthy; responsible; as, a substantial freeholder.
Example Sentences:
(1) The predicted non-Lorentzian line shapes and widths were found to be in good agreement with experimental results, indicating that the local orientational order (called "packing" by many workers) in the bilayers of small vesicles and in multilamellar membranes is substantially the same.
(2) 10D1 mAb induced a substantial proliferation of peripheral blood T cells when cross-linked with goat anti-mouse Ig antibody.
(3) Estimates of potential for gastrointestinal side effects using the rat enteropooling assay and in vivo monkey effects indicate that diarrhea will be substantially reduced with retention of uterine stimulating potency.
(4) Previous studies in this laboratory with particulate Mn3O4 have shown that preweanling rats have substantially higher tissue Mn concentrations than similarly treated adults, indicating possible differences in uptake or elimination or both.
(5) A more substantial decrease was found in Aberdeen and the larger towns near to Aberdeen than in the smaller towns further from the city.
(6) In contrast, human breast milk contained substantially increased levels of immunoreactive PTHrP.
(7) It was found that there was a substantial increase in mortality rates in the area under the jets where there was large noise radiation.
(8) But the amount of time spent above SPA has differed substantially between men and women due to women both living longer, and reaching state pension age earlier.
(9) Although statistical analysis did not show dramatic changes in all these parameters, some individual extreme values were substantially altered.
(10) Cholestyramine resin was beneficial in reducing stool bulk but had no substantial effect on fat absorption.
(11) Accordingly, LPA proved an extremely stable characteristic which did not show any substantial variations in the course of five years.
(12) This hypothesis is difficult to substantiate with direct measurements using human subjects.
(13) Mitogen-stimulated cells always contain substantially higher levels of LDL receptor messenger RNA than corresponding resting cells.
(14) Considerable glucose 6-phosphatase activity survived 240min of treatment with phospholipase C at 5 degrees C, but in the absence of substrate or at physiological glucose 6-phosphate concentrations the delipidated enzyme was completely inactivated within 10min at 37 degrees C. However, 80mM-glucose 6-phosphate stabilized it and phospholipid dispersions substantially restored thermal stability.
(15) Amine metabolites, 5-hydroxyindoleacetic acid (5HIAA), and homovanillic acid (HVA) were not substantially affected by sleep deprivation, although there was a significant interaction of clinical response and direction of 3-methoxy-4-hydroxyphenylglycol (MHPG) change.
(16) The department of dietetics at a large teaching hospital has substantially reduced its food and labor costs through use of computerized systems that ensure efficient inventory management, recipe standardization, ingredient control, quantity and quality control, and identification of productive man-hours and appropriate staffing levels.
(17) Substantial percentages of both physicians and medical students reported access to drugs, family histories of substance abuse, stress at work and home, emotional problems, and sensation seeking.
(18) For further education, this would be my priority: a substantial increase in funding and an end to tinkering with the form of qualifications and bland repetition of the “parity of esteem” trope.
(19) The family members of depressed patients with six or more groups of DSM-III symptoms of major depression exhibited substantially higher rates of mood disorders than the family members of depressed patients with fewer than six groups of symptoms and the family members of patients with nonaffective disorders.
(20) The results presented here substantiate the hypothesis that in S. cerevisiae trehalose supplies energy during dormancy of the spores and not during the germination process.