(n.) The Altar; a southern constellation, south of the tail of the Scorpion.
(n.) A name of the great blue and yellow macaw (Ara ararauna), native of South America.
Example Sentences:
(1) The antitumor effect of C18PCA and Ara-C was investigated against the P388 ascites tumor in BDF1 mice.
(2) However, the walker 256 intramuscular tumor did not respond to ARA-C capsules implanted, and the animals died at the same rate as the controls, with large ulcerated tumor masses and some metastasis.
(3) 5 heavily pretreated patients with chronic lymphocytic leukaemia or non-Hodgkin lymphoma resistant to alkylating agents were treated with low-dose cytosine arabinoside (ARA-C).
(4) Rat liver microsomes demethylated ara-DMAP much more rapidly than human liver microsomes did.
(5) Enhanced ara-CTP formation was observed in cells lacking cytidine deaminase (L1 210 and HL60), indicating that 3-deazauridine inhibition of deoxycytidylate deaminase may be important in this drug interaction.
(6) This study demonstrates the mutagenic properties of F-ara-A and ara-A and provides evidence for mechanisms by which the arabinosyl nucleosides induce mutation.
(7) Patient cells had low rates for ara-C transport as compared with human and murine experimental cells and correspondingly low binding capacities for the nucleoside transport inhibitor, nitrobenzylmercaptopurine riboside (NBMPR).
(8) The inhibitions by ara-GTP and 9-beta-D-arabinofuranosyladenine 5'-triphosphate were due to competition or partial competition 5'-triphosphate were due to competition or partial competition with deoxynucleoside triphosphate with the same base.
(9) The incorporation of F-ara-A monophosphate into mRNA resulted in premature termination of the RNA transcript and impaired its functioning as a template for protein synthesis.
(10) Pharmacological studies of 5'-esters of 1 beta-D-arabinofuranosylcytosine (ara-C) were performed in three species (mouse, pig, and man).
(11) These results provide some support for the view that cell kill may not be the only basis for the chemotherapeutic effectiveness of ara-C.
(12) Accelerating test at a constant temperature indicates that liposome-entrapped Ara-A has certain chemical stability.
(13) Although statistically significant, the effect of DP on ara-CTP retention in AML blasts was much less pronounced than that previously observed in L5178Y leukemia.
(14) He was treated with the combination chemotherapy of BACOD with high dose ara-C or methotrexate followed by 4 doses of autologous LAK cell infusion resulting in no significant response.
(15) Regardless whether cyclo-C or ara-C is injected, the plasma decay curve of the resultant ara-C is biphasic, with calculated half-lives of 40 min and 2-2.5 hr.
(16) Serial measurements of DNA synthesis and net intracellular ara-C metabolism demonstrated marked increases in both determinants in day 8 residual tumor when compared with the pretreatment cells for newly diagnosed adults achieving complete remission but not for TST-refractory patients.
(17) Determination of the intracellular content of the active metabolite of ara-C, ara-CTP, excluded more prolonged retention of the drug as the basis for potentiation of cytotoxicity.
(18) With the aim of improving the treatment of AML patients the activities of selected nucleoside metabolizing enzymes of possible implication for the initial metabolism of Ara-C have been studied in leukemic and normal cells.
(19) Ara-C. We conclude that prophylactic CNS therapy may cause cognitive dysfunctions.
(20) This was possible because the Ara test, for volatile compounds (such as vinyl bromide), did not require the use of special vaporization techniques, which are difficult to evaluate quantitatively for mutagenic activity.
Arf
Definition:
Example Sentences:
(1) We have previously shown that, with moderate hydration (2.5 L) of the recipient, together with rapid infusion of 250 ml of mannitol 20% just before clamp removal, the incidence of ARF decreased to below 10%.
(2) The factors predisposing to and complicating acute renal failure (ARF) in the medical intensive care unit (ICU), and their relative influence on outcome during ARF are unclear.
(3) Frusemide has been given to try to prevent this change in glycerol-induced ARF because of its effect in redistributing renal blood flow from medulla to cortex.
(4) Five different human ARFs have been identified by cDNA cloning.
(5) Studies of calcium antagonists in humans with ARF have been confined to patients undergoing renal transplantation.
(6) With an additional procedure of adrenalectomy (BN + Ax), the enzyme activity failed to show any increase in ARF rats produced by BN.
(7) Glycerol-induced ARF in rats or rabbits has been studied to investigate the pathogenesis of myoglobinuria-associated ARF.
(8) The results demonstrate that redistribution of ARF to the vesicle membrane correlates with the intravesicular pH established by a vacuolar-type H(+)-ATPase.
(9) Uptake of tetraethylammonium with or without an H+ gradient was decreased in membrane vesicles from ARF rats compared with normal rats.
(10) Hybridization of a bovine ARF 2 cDNA under low stringency with mammalian poly(A)+ RNA resulted in multiple bands that were subsequently assigned to the known ARF genes using ARF-specific oligonucleotide probes.
(11) (2) The interstitium of the cortex and of the outer stripe of the outer medulla is significantly widened in most cases of ARF.
(12) These were characterized by ballooning of the capillaries, thickening and splitting of glomerular basement membrane (GMB), fibrin thrombi in the capillaries, and mesangial cell proliferation most prominently seen in Ecchis carinatus bites resulting in ARF.
(13) ARF was centered in the inner city, where the incidence among black children reached 15.21.
(14) The renin-angiotensin system does not seem to contribute to the reduction of renal function in norepinephrine-induced ARF in dogs.
(15) It is concluded that reciprocal changes in RA and RE are the immediate cause of filtration failure in this form of ARF and that, in the virtual absence of filtration, tubular leakage can play no important role.
(16) No significant differences were present between both groups when they were analyzed for ARF incidence (15% vs 23.8%); overall incidence was 19.5%.
(17) Hospital records from all Swedish children 0-15 years old diagnosed as having acute rheumatic fever (ARF) during 1971-80 were studied.
(18) The spectrum and outcome of acute renal failure (ARF) were studied in 205 children aged between 1 month and 12 yr.
(19) Its presence in Giardia is consistent with the view that ARF emerged before the divergence of this protozoan from other eukaryotes (approximately 1.5 billion years ago), and that an ARF-like protein may have been the ancestor of several other classes of signal-transducing guanine nucleotide-binding proteins, including the alpha subunits of the heterotrimeric G proteins.
(20) The rate of carditis (3 of 10 patients) was similar to that in older studies of adults with ARF.