(1) Plasma concentrations of adriamycin and adriamycinol were measured in patients with acute nonlymphocytic leukemia during remission induction therapy with araC adriamycin and cytosine arabinoside.
(2) A retrospective analysis of charts from 15 patients treated with DNR-AraC was used to identify 228 items of cost, including general cost, diagnostic, supportive care, and chemotherapy.
(3) Data presented in this report demonstrate that ToxT is similar to the AraC family of transcriptional activators identified in a variety of gram-negative bacteria.
(4) The nucleotide sequence of the araC gene of C. freundii is 83% homologous to the araC genes of both E. coli and S. typhimurium, but only 60% homologous to that of E. carotovora with respect to the regions they share.
(5) The mutational analysis presented in this paper suggests that both autoregulatory and activator functions are localized to the same determinants of the AraC protein and that the amino acid sequence within the carboxy-terminal region of AraC protein is important for site-specific DNA binding.
(6) In the GM-CSF plus AraC group, 4 out of the 7 patients who completed the treatment showed an improvement of neutropenia as well as anaemia.
(7) The results obtained suggest the importance of tumor ARAC in the tumoral levels of E2 and reinforce the possible biologic significance of tumor ARAC, especially in postmenopausal breast carcinoma patients.
(8) The structure of the araC-containing decamer was solved by the molecular replacement method and refined by the constrained least-squares refinement procedure to obtain a final R factor of 0.187 using 2349 [greater than 2.0 sigma(F)] observed reflections to a resolution of 1.6 A.
(9) Combinations of 1-beta-D-arabinofuranosylcytosine (araC), bleomycin (BLM) or adriamycin (ADM) with the dipeptide bestatin do not result in an enhanced in vitro cytotoxicity in the macrophage-free L5178y mouse lymphoma cell system.
(10) Measurement of the net number of ions apparently displaced as AraC protein binds DNA and of fluorescence changes in the protein lead to the following picture.
(11) Experiments on the AraC regulatory protein of Escherichia coli suggest a mechanism that DNA-binding proteins can use to reduce potentially drastic alterations in their affinity for DNA resulting from changes in salt concentration.
(12) Activation of the polysaccharidic carboxyl group by isobutylchloroformiate and formation of a peptide bond via 4-NH2 group of araC was used for a coupling reaction.
(13) Five patients died in aplasia due to infections, one additional patient succumbed to HD-araC related CNS toxicity.
(14) Single administration of PGA-araC or CMG-araC increased the survival time 1.5 x or 1.7 x, respectively, compared with araC in vivo in L1210-leukemia-bearing mice.
(15) A deoxycytidine kinase-deficient variant of HL60 cells (HL60-araC), isolated by its resistance to 1-beta-D-arabinofuranosyl cytosine (ara-C), shows cross-resistance to the differentiation-inducing and growth-inhibitory effects of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3).
(16) It’s not enough at all,” said Araceli Belaez, 40, lining up for groceries at a supermarket in the Caracas slum of Catia.
(17) Morphometric analysis of the outgrowth zone revealed a statistically significant decrease in the incidence of fibroblastic-reactive microglial cells (from 12 to 0%), and a significant increase in the incidence of protoplasmic astrocytic-epithelial cells (from 82 to 96%), for AraC-treated explants compared to controls.
(18) The Salmonella typhimurium araC gene product is known to be susceptible to proteolytic degradation.
(19) If endoreduplicated cells originate from cells which have undergone rereplication of DNA segments randomly distributed over the genome during araC treatment, the diplochromosomes should exhibit lightly stained bands.
(20) Short treatment (up to 1 h) of cytosine arabinoside (araC) increases the frequencies of aberrations induced by X-rays in human lymphocytes, evaluated at the first mitosis following stimulation, or as prematurely condense chromosomes of G0 nuclei.
Brace
Definition:
(n.) That which holds anything tightly or supports it firmly; a bandage or a prop.
(n.) A cord, ligament, or rod, for producing or maintaining tension, as a cord on the side of a drum.
(n.) The state of being braced or tight; tension.
(n.) A piece of material used to transmit, or change the direction of, weight or pressure; any one of the pieces, in a frame or truss, which divide the structure into triangular parts. It may act as a tie, or as a strut, and serves to prevent distortion of the structure, and transverse strains in its members. A boiler brace is a diagonal stay, connecting the head with the shell.
(n.) A vertical curved line connecting two or more words or lines, which are to be taken together; thus, boll, bowl; or, in music, used to connect staves.
(n.) A rope reeved through a block at the end of a yard, by which the yard is moved horizontally; also, a rudder gudgeon.
(n.) A curved instrument or handle of iron or wood, for holding and turning bits, etc.; a bitstock.
(n.) A pair; a couple; as, a brace of ducks; now rarely applied to persons, except familiarly or with some contempt.
(n.) Straps or bands to sustain trousers; suspenders.
(n.) Harness; warlike preparation.
(n.) Armor for the arm; vantbrace.
(n.) The mouth of a shaft.
(v. t.) To furnish with braces; to support; to prop; as, to brace a beam in a building.
(v. t.) To draw tight; to tighten; to put in a state of tension; to strain; to strengthen; as, to brace the nerves.
(v. t.) To bind or tie closely; to fasten tightly.
(v. t.) To place in a position for resisting pressure; to hold firmly; as, he braced himself against the crowd.
(v. t.) To move around by means of braces; as, to brace the yards.
(v. i.) To get tone or vigor; to rouse one's energies; -- with up.
Example Sentences:
(1) Gains in gait pattern, ease of bracing, and reduced pelvic obliquity were noted.
(2) We assessed the relative restraints that are provided by fourteen currently available functional knee-braces, using six limbs in cadavera.
(3) During the last 21 months, 12 additional children have been managed with a more stringent protocol combining neck immobilization in a rigid cervical brace for 3 months and restriction of both contact and noncontact sports, together with a major emphasis on patient compliance.
(4) The classic scoliosis was resistant to brace treatment; bracing failed in 70% of patients, necessitating spinal fusion.
(5) Cotrel-Dubousset instrumentation (CDI) has been gaining popularity in scoliosis surgery because of their improved rigidity which can obviate the need for a brace in most cases.
(6) The brace extended from the proximal radius and ulna to the level of the radial styloid and allowed a full range of movement at the radiocarpal joint.
(7) The purpose of this project was to determine if commercially available braces could be shown to produce objective evidence of medial stabilization of the knee.
(8) The schemes will be scrutinised for evidence that the government has accepted criticism that it is not acting fast or hard enough to reverse the continuing slump in the economy, with ministers braced for further bad news on jobs and investment over the summer.
(9) Effective bracing of the severely spastic wrist and hand may not be possible.
(10) All patients were placed in Minerva braces postoperatively.
(11) Contact between the owner of the Times and the Sun and Ofcom in the run-up to Christmas left insiders at News Corp's Wapping headquarters braced for a referral.
(12) It is concluded that treatment with a patellar brace with a lateral pad is not likely to succeed in the majority of patients with retropatellar pain syndrome.
(13) Costa got his second while David Silva and substitute Álvaro Morata also got braces and Vitolo opened his international account as the former world champions ran riot.
(14) Rattled investors brace for big week as Federal Reserve considers rate increase Read more The Dow Jones industrial average fell 114 points, or 0.7%, to 16,528.
(15) Anti-globalisation activists and international bankers are bracing themselves for a week of street action and possible confrontation planned to coincide with the annual meeting of the World Bank and International Monetary Fund in Prague.
(16) Then, in English, a simple statement that has come to define a Japanese summer of public discontent, the likes of which it has not seen in a generation: “This is what democracy looks like!” Amid the trade union and civic group banners were colourful, bilingual placards held aloft by a new generation of activists who have assumed the mantle of mass protest as Japan braces for the biggest shift in its defence posture for 70 years.
(17) This retrospective study of lateral electrical surface stimulation (LESS) treatment for patients with progressive idiopathic scoliosis was performed to document patient compliance in the standard electrical stimulation program and to gain objective data to perform a relative comparison of electrical stimulation and bracing compliance.
(18) The brace has been used for 22 years and found practical and reliable.
(19) Shortening in severe comminution was the main complication and was not controlled by supplementary cast-bracing.
(20) Defensive players who wore prophylactic knee braces had statistically fewer knee injuries than players who served as controls.