(1) Plasma concentrations of adriamycin and adriamycinol were measured in patients with acute nonlymphocytic leukemia during remission induction therapy with araC adriamycin and cytosine arabinoside.
(2) A retrospective analysis of charts from 15 patients treated with DNR-AraC was used to identify 228 items of cost, including general cost, diagnostic, supportive care, and chemotherapy.
(3) Data presented in this report demonstrate that ToxT is similar to the AraC family of transcriptional activators identified in a variety of gram-negative bacteria.
(4) The nucleotide sequence of the araC gene of C. freundii is 83% homologous to the araC genes of both E. coli and S. typhimurium, but only 60% homologous to that of E. carotovora with respect to the regions they share.
(5) The mutational analysis presented in this paper suggests that both autoregulatory and activator functions are localized to the same determinants of the AraC protein and that the amino acid sequence within the carboxy-terminal region of AraC protein is important for site-specific DNA binding.
(6) In the GM-CSF plus AraC group, 4 out of the 7 patients who completed the treatment showed an improvement of neutropenia as well as anaemia.
(7) The results obtained suggest the importance of tumor ARAC in the tumoral levels of E2 and reinforce the possible biologic significance of tumor ARAC, especially in postmenopausal breast carcinoma patients.
(8) The structure of the araC-containing decamer was solved by the molecular replacement method and refined by the constrained least-squares refinement procedure to obtain a final R factor of 0.187 using 2349 [greater than 2.0 sigma(F)] observed reflections to a resolution of 1.6 A.
(9) Combinations of 1-beta-D-arabinofuranosylcytosine (araC), bleomycin (BLM) or adriamycin (ADM) with the dipeptide bestatin do not result in an enhanced in vitro cytotoxicity in the macrophage-free L5178y mouse lymphoma cell system.
(10) Measurement of the net number of ions apparently displaced as AraC protein binds DNA and of fluorescence changes in the protein lead to the following picture.
(11) Experiments on the AraC regulatory protein of Escherichia coli suggest a mechanism that DNA-binding proteins can use to reduce potentially drastic alterations in their affinity for DNA resulting from changes in salt concentration.
(12) Activation of the polysaccharidic carboxyl group by isobutylchloroformiate and formation of a peptide bond via 4-NH2 group of araC was used for a coupling reaction.
(13) Five patients died in aplasia due to infections, one additional patient succumbed to HD-araC related CNS toxicity.
(14) Single administration of PGA-araC or CMG-araC increased the survival time 1.5 x or 1.7 x, respectively, compared with araC in vivo in L1210-leukemia-bearing mice.
(15) A deoxycytidine kinase-deficient variant of HL60 cells (HL60-araC), isolated by its resistance to 1-beta-D-arabinofuranosyl cytosine (ara-C), shows cross-resistance to the differentiation-inducing and growth-inhibitory effects of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3).
(16) It’s not enough at all,” said Araceli Belaez, 40, lining up for groceries at a supermarket in the Caracas slum of Catia.
(17) Morphometric analysis of the outgrowth zone revealed a statistically significant decrease in the incidence of fibroblastic-reactive microglial cells (from 12 to 0%), and a significant increase in the incidence of protoplasmic astrocytic-epithelial cells (from 82 to 96%), for AraC-treated explants compared to controls.
(18) The Salmonella typhimurium araC gene product is known to be susceptible to proteolytic degradation.
(19) If endoreduplicated cells originate from cells which have undergone rereplication of DNA segments randomly distributed over the genome during araC treatment, the diplochromosomes should exhibit lightly stained bands.
(20) Short treatment (up to 1 h) of cytosine arabinoside (araC) increases the frequencies of aberrations induced by X-rays in human lymphocytes, evaluated at the first mitosis following stimulation, or as prematurely condense chromosomes of G0 nuclei.
Trace
Definition:
(n.) One of two straps, chains, or ropes of a harness, extending from the collar or breastplate to a whiffletree attached to a vehicle or thing to be drawn; a tug.
(v. t.) A mark left by anything passing; a track; a path; a course; a footprint; a vestige; as, the trace of a carriage or sled; the trace of a deer; a sinuous trace.
(v. t.) A very small quantity of an element or compound in a given substance, especially when so small that the amount is not quantitatively determined in an analysis; -- hence, in stating an analysis, often contracted to tr.
(v. t.) A mark, impression, or visible appearance of anything left when the thing itself no longer exists; remains; token; vestige.
(v. t.) The intersection of a plane of projection, or an original plane, with a coordinate plane.
(v. t.) The ground plan of a work or works.
(v. t.) To mark out; to draw or delineate with marks; especially, to copy, as a drawing or engraving, by following the lines and marking them on a sheet superimposed, through which they appear; as, to trace a figure or an outline; a traced drawing.
(v. t.) To follow by some mark that has been left by a person or thing which has preceded; to follow by footsteps, tracks, or tokens.
(v. t.) Hence, to follow the trace or track of.
(v. t.) To copy; to imitate.
(v. t.) To walk over; to pass through; to traverse.
(v. i.) To walk; to go; to travel.
Example Sentences:
(1) Glyceryl p-aminobenzoate and amyl p-dimethyl-aminobenzoate were labeled on 1 and 3 sunscreens, respectively, but glyceryl p-aminobenzoate was not found in any of them and only traces of amyl p-dimethylaminobenzoate were found in 1 sunscreen.
(2) Throughout the entire cultivation cytidyl derivatives occurred in trace quantities.
(3) persisted and was more abnormal in 23% of the cases including specific tracings in 37%.
(4) Traces of the sulphoxide of butylmercapturic acid have been found in rat urine but not in rabbit urine.
(5) No 7 beta-hydroxysteroid dehydrogenase activity and only a trace of 7 alpha-hydroxysteroid dehydrogenase activity could be demonstrated when bile acid was deleted from the growth medium.
(6) Silicon, a relatively unknown trace element in nutritional research, has been uniquely localized in active calcification sites in young bone.
(7) Although various micronutrients (vitamins and trace elements) have also been found to have either a positive or negative association, findings were more clear-cut for the different food items contributing the micronutrients than for the specific micronutrients themselves.
(8) Methods used in tracing and improving cooperation of subjects are described.
(9) Her black persona unravelled this week when Ruthanne and Larry Dolezal, a couple named on her Montana birth certificate as her biological parents, told Spokane’s KREM 2 News that her ancestry was German and Czech, with traces of Native American.
(10) they are shown to inhibit in vitro the release of iron from acidified host cell cytosol, consisting mostly of hemoglobin, a process that could provide this trace element to the parasite.
(11) Thus, the carotid pulse tracing provides an accurate reproduction of the morphology of the pressure tracing recorded from the ascending aorta, and when calibrated by peripheral blood pressure measurement, it can be used to calculate LV pressure throughout ejection.
(12) Mutant C grew anaerobically in the light, whereas mutant G1 was light sensitive and produced only trace amounts of bacteriochlorophyll a (0.6 mumole per ml of protein).
(13) The effect was shown to be due to caldesmon and not to a trace contaminant by its full reversibility after addition of a monospecific caldesmon antibody.
(14) Of 15 organochlorine compounds analyzed, trace amounts mainly of p,p-DDE and polychlorinated biphenyls (PCBs) were detected, but could not be quantitated.
(15) Fifty physiologically characterized units were injected with horseradish peroxidase (HRP) or Lucifer yellow CH (LY) and their processes were traced to the crista.
(16) Polysomnography has revealed that this drug has several interesting qualities that benzodiazepines do not possess: stages 3-4 increase, stage 2 is unchanged or slightly reduced and no abnormal changes are detected on the EEG tracing.
(17) We find that the labelled cell has a myelinated axon, but that the axon loses its myelin within 50 microns of the soma and has not yet been traced further.
(18) He is likely to propose increased funding of plant disease experts, the stepping up of surveillance at ports of entry and a Europe-wide "plant passport" system to trace the origins of all plants coming into Britain.
(19) In addition, the postulated personality for PD may predispose to hard work, perspiration, and increased exposure to putative trace elements in the water supply.
(20) The voltage trace is then analysed with a piece of transparent paper, on which lines corresponding to solutions of the diffusion equation convert the time axis of the voltage trace into a concentration axis.