(a.) Steep and lofty, in a literal sense; hard to climb.
(a.) Attended with great labor, like the ascending of acclivities; difficult; laborious; as, an arduous employment, task, or enterprise.
Example Sentences:
(1) Shaping and fine working of restorations necessitated by cervical lesions, abrasions at the necks of teeth, or root surface caries can often be arduous to complete.
(2) Greece standoff over €86bn bailout eases after Brussels deal Read more But while the bailout chiefs are poised to agree on a route map, the journey for the Greek people seems no less long and arduous.
(3) Such sentiments are not uncommon in job agencies, particularly those that specialise in factory and food work, where labour demand is variable and geographically shifting, and conditions often arduous.
(4) Although the technique is costly and arduous, grafting patients who are severely burned with cultured epidermal autografts has proved to be a life-saving measure where few alternatives exist.
(5) Kim Jong-un has little to offer in the way of policy except more of the same "Arduous march” North Koreans have had to endure since 1993.
(6) The confidence vote was but one step in a long and arduous journey to putting near-bankrupt Greece back on its feet – financially, politically and increasingly socially – barely a year after it secured €110bn (£97bn) in emergency aid, the biggest bailout in western history.
(7) After all, it was the state system that allowed an estimated one million people to starve during the ‘arduous march’ famine of the late 1990s .
(8) The etiopathogenesis is still controversial and differential diagnosis, especially from giant cell tumors of bone, is arduous.
(9) But financial constraints were arduous and interminable, and he declined the invitation to renew his contract.
(10) Legislative change is arduous and can be slow to come.
(11) John Terry insists players support José Mourinho to turn around Chelsea slump Read more Most obviously there is the fact that Mourinho is again finding being Chelsea manager for a third successive season an arduous undertaking.
(12) Click here to view video Dean Cundey, director of photography Romancing the Stone had been a very muddy, arduous shoot, so Back to the Future was simple by comparison – most of it was shot on the lot at Universal, or in neighbourhoods in Pasadena.
(13) Deficit reduction is a difficult and arduous task, which will put pressures on both business and consumers over the coming years.
(14) We are greatly heartened there will not be a long, arduous wait for the next milestone to arrive,” he said.
(15) Using Khi-2 tests and logistic models, the negative health effects of arduous shift work appear to be less than expected.
(16) | Anne Perkins Read more The failure of different providers of services to join up and share information has been highlighted repeatedly over the years; some efforts have been made, such as the integration of health and social care, but it’s often an arduous and unenviable task .
(17) This prevents unnecessary delay in treatment and makes contact tracing less arduous.
(18) Automated DNA sequencing methods using robotic workstations have been previously reported, however it is often an arduous task to import these technologies into a laboratory.
(19) The reconstruction of nasal deformities after trauma or surgical procedures presents an arduous task for the reconstructive surgeon.
(20) Freud considered the third phase to be an arduous task for the patient, and a trial of patience for the analyst, probably because of two additional determinants: (1) the patient's 'will' to change, and (2) his re-adaptation to his environment.
Exhausting
Definition:
(p. pr. & vb. n.) of Exhaust
(a.) Producing exhaustion; as, exhausting labors.
Example Sentences:
(1) Peak Expiratory Flow and Forced Expiratory Mean Flows in the ranges 0-25%, 25-50% and 50-75% of Forced Vital Capacity were significantly reduced in animals exposed to gasoline exhaust fumes, whereas the group exposed to ethanol exhaust fumes did not differ from the control group.
(2) The use of functional test with the ACTH administration demonstrated organic affection of the CNS to sharply aggravate the weakening and even the exhaustion of the functional reserves of the glomerular and the reticular zones of the adrenal cortex developing during thyrotoxicosis, and also the reserve possibilities of the sympathico-adrenal system.
(3) Administration of one of the precursors of noradrenaline l-DOPA not only prevented the decrease in tissue noradrenaline content in myocardium, but restored completely its reserves, exhausted by electrostimulation of the aortic arch.
(4) Respiratory muscle endurance at a given level of load was assessed from the time of exhaustion and from the time course of the change in the power spectrum (centroid frequency) of the diaphragm electromyogram (EMG).
(5) 9 Women performed plantarflexion and dorsalflexion with maximum strength and at constant load of 60% MVC to exhaustion.
(6) The results suggest that, in PMA-stimulated neutrophils, cytosolic activation factors may be consumed or exhausted with an increasing period of time after the stimulation of neutrophils, and that the affinity of PMA-stimulated neutrophil NADPH oxidase to NADPH may almost be the same as that of control neutrophil oxidase.
(7) During heavy exercise at 65-75% of VO2 max, time till exhaustion correlates with the pre-exercise muscle glycogen concentration and exhaustion coincides with empty glycogen stores.
(8) Glycogen content of the rabbit vastus lateralis muscle was also significantly depleted after exhaustive, intermittent exercise.
(9) Currently, entitlement to CTC for families with one to three children is fully exhausted when gross household earnings reach about £26,000 and £40,000 a year respectively.
(10) Pseudomonas aeruginosa PAO and 15 other strains of this species synthesized a polyester with 3-hydroxydecanoate as the main constituent (55 to 76 mol%) if the cells were cultivated in the presence of gluconate and if the nitrogen source was exhausted; 3-hydroxyhexanoate, 3-hydroxyoctanoate, and 3-hydroxydodecanoate were minor constituents of the polymer.
(11) It is concluded that acute intravenous injections of AVT augment the LH-releasing activity of LRH; chronic treatment for 48 h, however, with LRH + AVT leads to a significant depression of plasma LH perhaps due to an exhaustion of the releasable pool of LH in the anterior pituitary.
(12) On exhaustion of NADH, with residual oxygen, decay occurs in two phases to give a form in which haem b and flavin are oxidized.
(13) Their lipid metabolism did not seem to be affected at least partially by NO3- exhaustion.
(14) She was so exhausted from her trip to London she said she might stay there for 48 hours.
(15) Are we moving from a culture where MPs stayed in parliament until booted out, to one where many do five years and move on, frustrated and exhausted?
(16) The effect of various fuel additives on the ability of platinum-palladium catalytic converters to remove the carbon monoxide and hydrocarbon components of automotive exhaust has been examined.
(17) Regional functional recovery following 2-minute CO was examined under two different conditions in eight dogs: patent coronary artery stenosis and fixed CSS that exhausted coronary reserve but did not cause a deficit in resting coronary flow or regional function.
(18) The reduction in the mechanical clearance in adult humans caused by exposure to high concentrations of diesel exhaust was found to be much less than that observed in rats.
(19) A timed sprint to exhaustion was performed after 45 min of exercise at 70% of VO2max, and a Wingate anaerobic test was used to measure total work and peak power.
(20) Oxygenator exhaust capnographic measurements systematically underestimated PaCO2 measured by a bench blood gas analyzer.