(n.) A plant, drug, or medicine, characterized by a fragrant smell, and usually by a warm, pungent taste, as ginger, cinnamon, spices.
Example Sentences:
(1) In granulosa cells containing full aromatase activity, treatment with cortisol and dexamethasone did not inhibit aromatization of androstenedione to estrogens whereas two known aromatase inhibitors (dihydrotestosterone and 4-androstene-3, 6, 17-trione) were effective.
(2) The chemical shift changes observed on the binding of trimethoprim to dihydrofolate reductase are interpreted in terms of the ring-current shift contributions from the two aromatic rings of trimethoprim and from that of phenylalanine-30.
(3) Enzyme-inhibiting ability for individual alkylphenols can be estimated based on the quantitative structure-activity relationship developed by Dewhirst (1980) and is a function of the free hydroxyl group, electron-donating ring substituents, and hydrophobic aromatic ring substituents.
(4) N-heterocyclic aromatics are environmentally important carcinogenic pollutants produced by incomplete combustion of organic material.
(5) Deviations from isotropic motion observed for the non-aromatic moieties are discussed.
(6) Aromatic adducts present in the digest that were resistant to nuclease P1 were thus 32P-labelled while unmodified nucleotides were not.
(7) The possible occupational cause of the disease, as more solvents in the mud have the structure of aromatic hydrocarbons is discussed.
(8) Interaction between aromatic diamidines (pentamidine, propamidine, and stilbamidine) and nucleic acids were studied to elucidate the mechanism underlying renal toxicity included by pentamidine in patients.
(9) The D-Phe peptides, which are cleaved especially rapidly by thrombin in water, have structures (in deuterated DMSO) in which the aromatic ring of the D-Phe residue is folded back over the Val or Pip residue.
(10) Results of enzyme immunoassay also showed that dipeptides composed of two aromatic amino acids were more inhibitory than dipeptides of which one residue was aromatic amino acid.
(11) The enzyme has a significant preference for substrates with a P1 Phe over those with the other aromatic amino acids Tyr and Trp.
(12) Their absorption spectra are at sufficiently long wavelength to be unobscured by cellular chromophores such as nucleotides and aromatic amin acids.
(13) As experimental findings indicated inhibitory action of aromatic retinoid on microtubule polymerisation and collagen metabolism of mesenchymal cells, we decided to treat 5 patients suffering from progressive systemic sclerosis as well as 3 patients with Sharp's syndrome with aromatic retinoid (Tigason).
(14) The results also demonstrated that there was not any apparent correlation between the receptor-binding avidities and in vitro monooxygenase enzyme-induction potencies for the most active polynuclear aromatic hydrocarbons.
(15) The complexes are produced by attachment of a carbon of the butenolide ring to an aromatic carbon of the nitro compound with formation of a charge-delocalized cyclohexadienate anion.
(16) Aromatization of [3H]androstenedione and [3H]19-hydroxyandrostenedione to [3H]estrone has been demonstrated to occur in one to two week old primary monolayer cultures of fetal rat hypothalamus.
(17) Both main-stream and side-stream cigarette smoke condensates and some fractions, containing water-soluble bases, water-insoluble bases, and polycyclic aromatic hydrocarbons, were found to induce AHH activity in lung and liver, the lung being induced to the greatest extent.
(18) The greater frequency of dysovulation in obese women, notably those who put on weight rapidly, is accompanied by numerous hormonal changes, including reduced sex hormone-binding globulin, increased ovarian and adrenal androgen production, increased peripheral aromatization of androgens to oestrogens, and altered gonadotropin pulsatile secretion.
(19) R-(+)-Nicotine is a substrate Km = 1.42 X 10(-5)M for an SAM-dependent guinea pig lung aromatic azaheterocycle N-methyltransferase, whereas S-(-)-nicotine acts as a competitive inhibitor (Ki = 6.25 X 10(-5)M) of the N-methylation of its antipode.
(20) In the group of patients with the hyperkinetic form the most significant changes were seen for valine, methionine, serine, alanine and cystine, while as the spectrum of aminoacids of the aromatic line is practically unchanged.
Olfactory
Definition:
(a.) Of, pertaining to, or connected with, the sense of smell; as, the olfactory nerves; the olfactory cells.
(n.) An olfactory organ; also, the sense of smell; -- usually in the plural.
Example Sentences:
(1) Most survivors reported a range of problems that they attributed to having had cancer: 35%, proven or perceived infertility; 24%, sexual problems; 31%, health and life insurance problems; 26%, a negative socioeconomic effect; and 51%, conditioned nausea, associated with visual or olfactory reminders of chemotherapy.
(2) Lectin binding and tridimensional reconstruction provided new information on the distribution of olfactory glomeruli and on regional and interspecific differences.
(3) Pathological changes may, thus, be initially confined to projecting and intrinsic neurons localized in cortical and subcortical olfactory structures; arguments are advanced which favor the view that excitotoxic phenomena could be mainly responsible for the overall degenerative picture.
(4) Fifteen days after axotomy of the olfactory nerves, two stained patterns which were numerously or sparsely labelled regions were observed.
(5) However, in early neonates, granule cells close to the lateral olfactory tract exhibited p75NGFR-ir.
(6) The olfactory organs of fishes are diversely developed.
(7) This observation provides corroboration for the identification of the principal CCK-I neuron in the rat olfactory bulb as the centrally projecting middle tufted cell.
(8) One PCR product hybridized to a 4.0 kb RNA concentrated in subpopulations of putative glutamatergic neurons including mitral cells of the olfactory bulb, pyramidal cells of layer V of the cerebral cortex, pyramidal cells of the piriform cortex, and pyramidal cells of field CA3 of the hippocampus.
(9) Olfactory bulbs are relatively smaller in felids than in canids or viverrids.
(10) A possible role of the olfactory tubercle in olfactory transduction will also be discussed.
(11) Microautoradiography showed that melanin-containing cells in the trunk and head kidney and in the olfactory rosettes also accumulated high amounts of radioactivity.
(12) Examines research in cognitive psychology, which has in the past paid little attention to the olfactory modality.
(13) The staining of HRP-immunopositive cell bodies indicates that the pallial regions studied receive afferent projections from the main olfactory bulb and are reciprocally interconnected by intrapallial associative fiber systems.
(14) The MA and BNST in general are involved in regulation of several sexually dimorphic functions, including aggression, sexual behavior, gonadotropin secretion and integration of olfactory information.
(15) The results also indicate that the two parts of the teleost olfactory bulb are differentiated not only functionally but also morphologically.
(16) Chemosensory cilia of olfactory receptor neurons contain an adenylate cyclase which is stimulated by high concentrations of odorants.
(17) The rhythmic waves induced by these ions were recorded in the olfactory bulb.
(18) Information about olfactory neuron microtubules may be applicable to neurons in general (e.g., the discovery that axons contain microtubules of uniform polarity was first made in the olfactory neuron) or to microtubules in other eukaryotic cells.
(19) Exposure to short photoperiod increased the number of immunoreactive cell bodies within the anterior hypothalamus and preoptic area (AHPOA) and also increased the optical density for staining of immunoreactive cell bodies in the AHPOA and olfactory peduncle.
(20) In younger animals, olfactory receptor cells were observed within the epithelial area isolating the septal organ from the olfactory epithelium, whereas this area was reported to be an exclusive respiratory region in adult rats.