(n.) A plant, drug, or medicine, characterized by a fragrant smell, and usually by a warm, pungent taste, as ginger, cinnamon, spices.
Example Sentences:
(1) In granulosa cells containing full aromatase activity, treatment with cortisol and dexamethasone did not inhibit aromatization of androstenedione to estrogens whereas two known aromatase inhibitors (dihydrotestosterone and 4-androstene-3, 6, 17-trione) were effective.
(2) The chemical shift changes observed on the binding of trimethoprim to dihydrofolate reductase are interpreted in terms of the ring-current shift contributions from the two aromatic rings of trimethoprim and from that of phenylalanine-30.
(3) Enzyme-inhibiting ability for individual alkylphenols can be estimated based on the quantitative structure-activity relationship developed by Dewhirst (1980) and is a function of the free hydroxyl group, electron-donating ring substituents, and hydrophobic aromatic ring substituents.
(4) N-heterocyclic aromatics are environmentally important carcinogenic pollutants produced by incomplete combustion of organic material.
(5) Deviations from isotropic motion observed for the non-aromatic moieties are discussed.
(6) Aromatic adducts present in the digest that were resistant to nuclease P1 were thus 32P-labelled while unmodified nucleotides were not.
(7) The possible occupational cause of the disease, as more solvents in the mud have the structure of aromatic hydrocarbons is discussed.
(8) Interaction between aromatic diamidines (pentamidine, propamidine, and stilbamidine) and nucleic acids were studied to elucidate the mechanism underlying renal toxicity included by pentamidine in patients.
(9) The D-Phe peptides, which are cleaved especially rapidly by thrombin in water, have structures (in deuterated DMSO) in which the aromatic ring of the D-Phe residue is folded back over the Val or Pip residue.
(10) Results of enzyme immunoassay also showed that dipeptides composed of two aromatic amino acids were more inhibitory than dipeptides of which one residue was aromatic amino acid.
(11) The enzyme has a significant preference for substrates with a P1 Phe over those with the other aromatic amino acids Tyr and Trp.
(12) Their absorption spectra are at sufficiently long wavelength to be unobscured by cellular chromophores such as nucleotides and aromatic amin acids.
(13) As experimental findings indicated inhibitory action of aromatic retinoid on microtubule polymerisation and collagen metabolism of mesenchymal cells, we decided to treat 5 patients suffering from progressive systemic sclerosis as well as 3 patients with Sharp's syndrome with aromatic retinoid (Tigason).
(14) The results also demonstrated that there was not any apparent correlation between the receptor-binding avidities and in vitro monooxygenase enzyme-induction potencies for the most active polynuclear aromatic hydrocarbons.
(15) The complexes are produced by attachment of a carbon of the butenolide ring to an aromatic carbon of the nitro compound with formation of a charge-delocalized cyclohexadienate anion.
(16) Aromatization of [3H]androstenedione and [3H]19-hydroxyandrostenedione to [3H]estrone has been demonstrated to occur in one to two week old primary monolayer cultures of fetal rat hypothalamus.
(17) Both main-stream and side-stream cigarette smoke condensates and some fractions, containing water-soluble bases, water-insoluble bases, and polycyclic aromatic hydrocarbons, were found to induce AHH activity in lung and liver, the lung being induced to the greatest extent.
(18) The greater frequency of dysovulation in obese women, notably those who put on weight rapidly, is accompanied by numerous hormonal changes, including reduced sex hormone-binding globulin, increased ovarian and adrenal androgen production, increased peripheral aromatization of androgens to oestrogens, and altered gonadotropin pulsatile secretion.
(19) R-(+)-Nicotine is a substrate Km = 1.42 X 10(-5)M for an SAM-dependent guinea pig lung aromatic azaheterocycle N-methyltransferase, whereas S-(-)-nicotine acts as a competitive inhibitor (Ki = 6.25 X 10(-5)M) of the N-methylation of its antipode.
(20) In the group of patients with the hyperkinetic form the most significant changes were seen for valine, methionine, serine, alanine and cystine, while as the spectrum of aminoacids of the aromatic line is practically unchanged.
Phenylene
Definition:
(n.) A hypothetic radical (C6H4) occurring in certain derivatives of benzene; as, phenylene diamine.
Example Sentences:
(1) Efficacy of polyvinyl chloride collars containing temephos [0,0'-(thiodi-4,1-phenylene) 0,0,0',0'-tetramethyl bis-(phosphorothioate)] was elevaluated in dogs and cats against the cat flea (Ctenocephalides felis).
(2) The PCAH's identified in SRF-carbon black were: anthracene, phenanthrene, fluoranthene, pyrene, benzo(mno)fluoranthene, chrysene, 1,2-benzanthracene, 9,10-dimethyl-1,2-benzanthracene, 1,2-benzopyrene, 3,4-benzopyrene, perylene, o-phenylene pyrene 1,2-benzoperylene, anthanthrene, and coronene.
(3) Inhibition of MDA production to below control levels using the antioxidant N,N'-diphenyl-phenylene diamine (DPPD) however, had no inhibitory effect on cocaine-induced cytotoxicity in either mouse or rat cells.
(4) Platelet function studies, both in vitro and in vivo of dl-4,5,6-trinor-3,7-inter-m-phenylene-3-oxa-PGE1, methyl ester (VIII) are presented.
(5) The retention of radioactivity in the heart was also significantly prolonged when the p-phenylene group was in this position.
(6) New 1,4-diarylimidazole and 1,4-pyrrolimidazol-phenylene derivatives were prepared in attempt to deepen S.A.R.
(7) The activity of diamfenetide (N,N'-[oxybis(2,1-ethan diyloxy-4,1-phenylene)] bis acetamide) was studied in lambs experimentally inoculated with Fasciola hepatica.
(8) Acute effects of 200 mg of orally given 4-[2-(methylamino)ethyl]-o-phenylene diisobutyrate hydrochloride (ibopamine hydrochloride) which is a new diisobutyric ester of N-methyldopamine, on hemodynamics and metabolism were evaluated in 11 patients with severe heart failure (New York Heart Association class IV).
(9) Moreover, it is supposed that MDI may give rise to cross-sensitization to p-phenylene diamine and chemically related compounds.
(10) Muscle fibres in transverse "semithin" sections of osmium-fixed and plastic embedded muscle tissue stained with p-phenylene-diamine has been classified into three types (M, INT and H) and correlated to the same fibres in neighboring sequential preincubated myofibrillar ATP-ase sections.
(11) Several N,N'-(p-phenylene)dioxamic acids were synthesized also in the same manner starting with the requisite p-phenylenediamines.
(12) A close correlation, but no equality was found between the fibre types classified according to the ATP-ase and the p-phenylene-diamine methods.
(13) 2 was conducted to determine the effects of varying the length of the ortho-phenylene-diamine (OPD) incubation time upon assay results.
(14) In an alternative, but less satisfactory synthesis of 10, the compound (5-nitro-1, 3-phenylene) biscarbamic acid diphenyl ester (11), or the corresponding diethyl ester 12, was converted by ammonolysis to 13.
(15) Dogs and cats were treated with 2% temephos [0,0'-(thiodi-p-phenylene) 0,0',0'-tetramethyl bis (phosphorothioate)] powder to evaluate its insecticidal activity against the cat flea (Ctenocephalides felis).
(16) This addition may result in the saturation of the bridgehead double bond, thus allowing the two triple bonds to approach each other, causing cyclization of the diyn-ene to form a phenylene diradical.
(17) The peak heart uptake and the loss of radioactivity from the myocardium of fasted Sprague-Dawley rats depended on the alkyl-chain length and p-phenylene position.
(18) The consequences of incorporating variable-length flexible and rigid tethers [poly(methylene), Z and E ethylene, m- and p-phenylene] between the two netropsin-like moieties on the DNA binding properties were assessed by DNase I footprinting.
(19) The analyzing column is packed with porous polymer beads of 2,6-diphenyl-1,4-phenylene oxide.
(20) Surprisingly it turned out that the domain structure of S1 with ADP trapped by p-phenylene-N, N'-dimaleimide (pPDM) thiol cross-linking almost does not differ from that of the nucleotide-free S1.