(n.) A plant, drug, or medicine, characterized by a fragrant smell, and usually by a warm, pungent taste, as ginger, cinnamon, spices.
Example Sentences:
(1) In granulosa cells containing full aromatase activity, treatment with cortisol and dexamethasone did not inhibit aromatization of androstenedione to estrogens whereas two known aromatase inhibitors (dihydrotestosterone and 4-androstene-3, 6, 17-trione) were effective.
(2) The chemical shift changes observed on the binding of trimethoprim to dihydrofolate reductase are interpreted in terms of the ring-current shift contributions from the two aromatic rings of trimethoprim and from that of phenylalanine-30.
(3) Enzyme-inhibiting ability for individual alkylphenols can be estimated based on the quantitative structure-activity relationship developed by Dewhirst (1980) and is a function of the free hydroxyl group, electron-donating ring substituents, and hydrophobic aromatic ring substituents.
(4) N-heterocyclic aromatics are environmentally important carcinogenic pollutants produced by incomplete combustion of organic material.
(5) Deviations from isotropic motion observed for the non-aromatic moieties are discussed.
(6) Aromatic adducts present in the digest that were resistant to nuclease P1 were thus 32P-labelled while unmodified nucleotides were not.
(7) The possible occupational cause of the disease, as more solvents in the mud have the structure of aromatic hydrocarbons is discussed.
(8) Interaction between aromatic diamidines (pentamidine, propamidine, and stilbamidine) and nucleic acids were studied to elucidate the mechanism underlying renal toxicity included by pentamidine in patients.
(9) The D-Phe peptides, which are cleaved especially rapidly by thrombin in water, have structures (in deuterated DMSO) in which the aromatic ring of the D-Phe residue is folded back over the Val or Pip residue.
(10) Results of enzyme immunoassay also showed that dipeptides composed of two aromatic amino acids were more inhibitory than dipeptides of which one residue was aromatic amino acid.
(11) The enzyme has a significant preference for substrates with a P1 Phe over those with the other aromatic amino acids Tyr and Trp.
(12) Their absorption spectra are at sufficiently long wavelength to be unobscured by cellular chromophores such as nucleotides and aromatic amin acids.
(13) As experimental findings indicated inhibitory action of aromatic retinoid on microtubule polymerisation and collagen metabolism of mesenchymal cells, we decided to treat 5 patients suffering from progressive systemic sclerosis as well as 3 patients with Sharp's syndrome with aromatic retinoid (Tigason).
(14) The results also demonstrated that there was not any apparent correlation between the receptor-binding avidities and in vitro monooxygenase enzyme-induction potencies for the most active polynuclear aromatic hydrocarbons.
(15) The complexes are produced by attachment of a carbon of the butenolide ring to an aromatic carbon of the nitro compound with formation of a charge-delocalized cyclohexadienate anion.
(16) Aromatization of [3H]androstenedione and [3H]19-hydroxyandrostenedione to [3H]estrone has been demonstrated to occur in one to two week old primary monolayer cultures of fetal rat hypothalamus.
(17) Both main-stream and side-stream cigarette smoke condensates and some fractions, containing water-soluble bases, water-insoluble bases, and polycyclic aromatic hydrocarbons, were found to induce AHH activity in lung and liver, the lung being induced to the greatest extent.
(18) The greater frequency of dysovulation in obese women, notably those who put on weight rapidly, is accompanied by numerous hormonal changes, including reduced sex hormone-binding globulin, increased ovarian and adrenal androgen production, increased peripheral aromatization of androgens to oestrogens, and altered gonadotropin pulsatile secretion.
(19) R-(+)-Nicotine is a substrate Km = 1.42 X 10(-5)M for an SAM-dependent guinea pig lung aromatic azaheterocycle N-methyltransferase, whereas S-(-)-nicotine acts as a competitive inhibitor (Ki = 6.25 X 10(-5)M) of the N-methylation of its antipode.
(20) In the group of patients with the hyperkinetic form the most significant changes were seen for valine, methionine, serine, alanine and cystine, while as the spectrum of aminoacids of the aromatic line is practically unchanged.
Pungent
Definition:
(v. t.) Causing a sharp sensation, as of the taste, smell, or feelings; pricking; biting; acrid; as, a pungent spice.
(1) While his organising framework was Marxian (beginning as "an attempt to understand the arts", as he said himself), the subjects included mountain-climbing, opera, jazz and sartorial and eating fashions as well as work patterns, class solidarity and the movements of international finance – all delivered in a marvellously flexible and pungent style.
(2) Capsaicin is a pungent irritant present in peppers of the Capsicum family.
(3) This variety is not considered in this series of reviews covering primary processing, production, international trade, chemistry, and biochemistry of functional components--the red keto carotenoids, the aromatic volatiles and the pungent capsaicinoids in Parts I to III.
(4) It has a metallic, pungently sweaty kick to it, as if someone has absorbed the fluids of a gym changing-room floor into a lump of gluey cheese-like matter.
(5) Administration of capsaicin (CAP) and its related pungent, nonanoyl vanillylamide (NVA) produced significant dose-dependent hypothermic response in mice at an ambient temperature of 24 degrees C. CAP was approximately equieffective to NVA in producing hypothermia.
(6) The Ned Waihopai River Sauvignon Blanc, Marlborough, New Zealand (£9.99, Waitrose ; Majestic ) There's all the pungent verdant grass-and-gooseberry of classic Kiwi sauvignon here to match with asparagus, plus the generosity of fruit and limey acidity that will work just as well with a mildly spicy and herby Vietnamese or Thai stir-fry.
(7) Capsaicin is the main pungent principle of hot pepper, which is consumed in high quantities by humans worldwide.
(8) An increase in catecholamine, especially epinephrine, secretion was observed not only on capsaicin infusion but also on piperine (a pungent principle of pepper) and zingerone (ginger) infusion.
(9) After 170 years, his rehabilitation is complete, and for Toledo his elongated figures and pungent colours are now an object of civic pride, as Gaudí is for Barcelona.
(10) It is anxiety at the great acceleration of social, economic and demographic change wrought by the age of globalisation, expressed most pungently in resentment of mass migration.
(11) Measurement of a reflex, transitory apnea produced upon inhalation of pungent chemicals holds promise as an objective indicator of the functional status of the CCS.
(12) The pain-mediating function of SP can be blocked selectively by capsaicin, the pungent component of red pepper, which leads to desensitization of the receptors and degeneration of the afferent C fibers without affecting other sensory qualities.
(13) Capsaicin, the pungent principal in red pepper, has been shown to damage small-diameter peptide-containing sensory neurons.
(14) When they first encounter their "admirer and pupil Zola" he strikes them as a "worn-out Normalien, at once sturdy and puny" but with "a vibrant note of pungent determination and furious energy".
(15) And yet the country has some of the most pungent views on immigration on the continent.
(16) Results show that the characteristics of the mutual effects of tastant and pungent stimulus depend on the particular tastant employed.
(17) This wasn't the usual loveless EastEnders bouquet – a sickly-sweet accompaniment to the ever-present stench of batter mix, rotting market produce and Phil Mitchell's blouson runoff – but a pungent, altogether denser concoction.
(18) Among the three new compounds, hazeleamide (3) was found to show a pungent taste and to exert a moderate antimalarial activity in an in vitro test system.
(19) While, sulfur-containing and volatile pungent principles, allylisothiocyanate (mustard, etc.)
(20) The non-pungent nonenoyl benzylamide produces neither hypothermia nor desensitization.7.