(v. t.) To render (a person) certain; to cause to feel certain; to make confident; to assure; to apprise.
(v. t.) To make (a thing) certain to the mind; to free from obscurity, doubt, or change; to make sure of; to fix; to determine.
(v. t.) To find out or learn for a certainty, by trial, examination, or experiment; to get to know; as, to ascertain the weight of a commodity, or the purity of a metal.
Example Sentences:
(1) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
(2) Prior to oral feeding, little or no ELA was detected in stools and endotoxinemia was ascertained in only six of 45 infants (13%).
(3) A total of 13 ascertainments of folate sensitive autosomal fragile sites is observed, of which 10q23 fragility appears to be the most frequent.
(4) A similar examination of the effects of PD was also carried out in vitro to ascertain whether PD itself or its metabolites are involved in its action.
(5) The purity and configuration of each isomer of the free acid and N-chloroacetylated derivative were ascertained by: (a) paper chromatography in five solvent systems, (b) elemental analysis, (c) Van Slyke nitrous acid determination of alpha-carbonyl carbon, and (d) Van Slyke ninhydrin determination of alpha-carbonyl carbon, and (e) optical rotation.
(6) In an anthropologic study of illness referral among Latin-American immigrants three phases were ascertained: First, there was extended use of self-treatment.
(7) In 20 adult patients with asthma, we evaluated bronchodilation to a single administration of metered-dose glycopyrrolate aerosol (GA) to ascertain its onset and duration of action along with evaluation of safety.
(8) 64% of the patients without nodular metastases and 45% of the patients with histologically ascertained nodular metastases and 45% of the patients with histologically ascertained nodular metastases survived the 3-year interval.
(9) The results indicated a very good comparability between the dot-blot assay and IF-tests, and this dot-blot method was ascertained as a simple and useful method for the scrub typhus serodiagnosis.
(10) Combinations of YM534 with other anti-cancer agents were examined to ascertain whether YM534 potentiated other anti-cancer agents against the KB cell line and its multidrug-resistant counterpart, VJ-300.
(11) Three experiments in person perception were conducted to investigate the conditions under which naive observers label an actor as aggressive and to ascertain how this label affects the reactions of the observers to the actor.
(12) This study was designed to ascertain the frequency of these problems in our RS patients, whether they were related to other clinical features of RS and what was the extent of the resulting disability.
(13) The nutritional requirements for optimal production of biologically active l-asparaginase by a strain of Escherichia coli have been ascertained.
(14) Fifty-seven strains of enterotoxigenic Escherichia coli isolated from humans and pigs and producing thermolabile (LT) enterotoxin were used to ascertain the efficiency of the Biken test compared to the passive immune haemolysis test (PIH), considered as very sensitive for detecting that enterotoxin.
(15) In the formation of the transformation index the difference between the two groups could be statistically ascertained.
(16) This was a highly significant (p less than 0.0001) predictor of 5-year total mortality, whose ascertainment was virtually complete.
(17) On the basis of segregating phenotypes, the genetic potentials of these compatible nocardiae were ascertained as follows: the formation of a diploid with subsequent segregation of parental or haploid recombinant genomes or both; persistence of the diploid through many generations; continuing reassortment of genetic information by multiple matings between parental or recombinant organisms; and, very probably, second-round recombinations within the diploid.
(18) Based on the ratio of plasma membrane marker enzyme activity determined in the nuclear preparation, the purity of the isolated nuclei was ascertained.
(19) The amount of free testosterone in the saliva was also ascertained for 23 of the subjects.
(20) In addition, re-analysis of previous investigations of the MAB underscores the importance of ascertaining the reading level of subjects prior to the administration of the MAB.
Determine
Definition:
(v. t.) To fix the boundaries of; to mark off and separate.
(v. t.) To set bounds to; to fix the determination of; to limit; to bound; to bring to an end; to finish.
(v. t.) To fix the form or character of; to shape; to prescribe imperatively; to regulate; to settle.
(v. t.) To fix the course of; to impel and direct; -- with a remoter object preceded by to; as, another's will determined me to this course.
(v. t.) To ascertain definitely; to find out the specific character or name of; to assign to its true place in a system; as, to determine an unknown or a newly discovered plant or its name.
(v. t.) To bring to a conclusion, as a question or controversy; to settle authoritative or judicial sentence; to decide; as, the court has determined the cause.
(v. t.) To resolve on; to have a fixed intention of; also, to cause to come to a conclusion or decision; to lead; as, this determined him to go immediately.
(v. t.) To define or limit by adding a differentia.
(v. t.) To ascertain the presence, quantity, or amount of; as, to determine the parallax; to determine the salt in sea water.
(v. i.) To come to an end; to end; to terminate.
(v. i.) To come to a decision; to decide; to resolve; -- often with on.
Example Sentences:
(1) This study was undertaken to determine whether the survival of Hispanic patients with squamous cell carcinoma of the head and neck was different from that of Anglo-American patients.
(2) It is supposed that delta-sleep peptide along with other oligopeptides is one of the factors determining individual animal resistance to emotional stress, which is supported by significant delta-sleep peptide increase in hypothalamus in stable rats.
(3) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(4) The prenatal risk determined by smoking pregnant woman was studied by a fetal electrocardiogram at different gestational ages.
(5) These results indicated that the PG determination was the most accurate predictor of fetal lung well-being prior to birth among the clinical tests so far reported.
(6) The nucleotide sequence of a 2.2-kb DNA fragment which contains the complete RAD7 gene was determined.
(7) We have determined the genomic structure of the fosB gene and shown that it consists of 4 exons and 3 introns at positions also found in the c-fos gene.
(8) We conclude that first-transit and blood-pool techniques are equally accurate methods for determining EF when the time-activity method of analysis is employed.
(9) It is quite interesting to analyse which gene of the virus determines the characteristics of the virus.
(10) Spectrophotometric determination of the sulfhydryl content in the animal tissue before (control) and after using 6,6'-Dithiodinicotinic acid is applied.
(11) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
(12) Quantitative determinations indicate that the amount of PBG-D mRNA is modulated both by the erythroid nature of the tissue and by cell proliferation, probably at the transcriptional level.
(13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(14) Complementarity determining regions (CDR) are conserved to different extents, with the first CDR region in all family members being among the most conserved segments of the molecule.
(15) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(16) In animal experiments pharmacological properties of the low molecular weight heparin derivative CY 216 were determined.
(17) Using the oocyte system to express size-fractionated mRNA, we have also determined that the mRNA coding for this protein is between 1.9-2.4 kilobases in length.
(18) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(19) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
(20) The serum concentration of hyaluronan (HYA) was determined in 59 patients with various myeloproliferative disorders, including 33 patients with idiopathic myelofibrosis.