(a.) Extremely rigid in self-denial and devotions; austere; severe.
(n.) In the early church, one who devoted himself to a solitary and contemplative life, characterized by devotion, extreme self-denial, and self-mortification; a hermit; a recluse; hence, one who practices extreme rigor and self-denial in religious things.
Example Sentences:
(1) Famously ascetic, teetotal and vegetarian, he meditates, practises yoga and shuns the trappings of office.
(2) There are several basic structures upon which anorexia nervosa could develop: hostility between mother and daughter, feministic protest, abandonnism, the ascetic structure, the reluctance against the being-thrown-on-the-world, asw.
(3) As Obama put it himself, decades later, "I was leading an ascetic existence, way too serious for my own good".
(4) Pitt says Malick is nothing like the ascetic monk he's often imagined to be.
(5) But the other point is that unilateral opting out might mean you end up living a somewhat ascetic life.
(6) Now, it's all too easy to portray the average politician as a policy-wonk fed since the age of 14 on position papers on social policy and party outreach, professionally married to the job, ascetically weaned day and night on the company of his or her fellow party workers and political researchers, never seeing daylight, never watching telly, never having any cultural development outside whatever serves their policy purview.
(7) He is described as ascetic, highly disciplined and unfazed by the prospect of violence.
(8) These studies (2, 3, 5, 6) have demonstrated that the high IgE responses induced in low responder mice can be substantially diminished, and even abolished, by passively transfusing serum or ascetic fluid from donor mice previously inoculated with mycobacterial-containing complete Freund's adjuvant (CFA).
(9) (Because obviously, no one minds if you win or lose a game of football – and at the full-time whistle, after meditating for a while, the players pool their wages with the fans, before shyly retiring to their modest homes and ascetic lifestyles.)
(10) They are both people who appeal to better human values.” The Dalai Lama leads an ascetic life, rising before dawn to meditate and spending much of his time reading, thinking and taking long walks before retiring to bed at about 8.30pm.
(11) We’re approaching a point where a significant number of people want to change.” Brand is hardly an ascetic, but he is learning about self-denial.
(12) But Mr Putin has ended that disarray and rehabilitated the KGB as the embodiment of the ascetic, incorruptible public service.
(13) Overshadowed by his father, competent but underwhelming as a minister and shadow minister, high-minded and ascetic in his habits, Benn had seemed set to go through a political life without leaving a great mark.
(14) It is the religious aspects of enigmatic Persia that helped put an 80-year-old exiled ascetic at the head of state 30 years ago, then the charismatic cleric Khatami in office 12 years ago, the honest son of a blacksmith – Ahmedinejad – four years ago, and the same yesterday.
(15) Kafka was slim and underweight throughout his life and showed an ascetic attitude and abjuration of physical enjoyment and pleasure (fasting, vegetarianism, sexual abstinence, emphasis on physical fitness).
(16) Takao is still considered an important religious site, so don't be surprised to find yourself sharing a trail with ascetic Buddhists on their way to pray at Yakuo-in temple or cleanse themselves beneath the freezing waterfalls of Biwa-daki or Hebi-daki.
(17) He likened himself to an ascetic and a house cat and said he rarely left the house, spending most of his days surfing the internet – though visitors have brought him piles of books.
(18) From the 9th century, Sufi ascetics wandered the Islamic world, attracting followers to their gentle form of mystical Islam (the word Sufi is often thought to have come from suuf - wool - from the woollen garments the holy men wore).
(19) In the pre-State era, Israeli society displayed an "ascetic" orientation with emphasis on austerity and egalitarianism.
(20) In the moment of victory Murray dropped his racket and turned, mouth agape, towards the nearest section of the crowd – by happy coincidence also the press box – before crumpling to his knees on Centre Court, overcome at the end point of a gruellingly ascetic, occasionally obsessive journey towards an unassailable career high.
Asperity
Definition:
(n.) Roughness of surface; unevenness; -- opposed to smoothness.
(n.) Roughness or harshness of sound; that quality which grates upon the ear; raucity.
(n.) Roughness to the taste; sourness; tartness.
(n.) Moral roughness; roughness of manner; severity; crabbedness; harshness; -- opposed to mildness.
(n.) Sharpness; disagreeableness; difficulty.
Example Sentences:
(1) The presence of proteins antigenically related to Bothrops asper myotoxins in various snake venoms, mainly from South America, was investigated by using polyclonal and monoclonal antibodies.
(2) The myotoxin shows partial immunologic identity with a myotoxic phospholipase A2 isolated from Bothrops asper venom.
(3) Mice that received antivenom (0.4 ml) by the iv or im route 15 min after im injection of B. asper venom (100 micrograms) had lower levels of plasma anti-myotoxin antibodies than controls injected with antivenom only, suggesting that at least a fraction of the antibodies combines with myotoxins in vivo.
(4) Metalloproteinase from the venom of Bothrops asper (proteinase G) is a glycoprotein with 1% neutral hexose and 3.5 moles of sialic acid per mole of protein.
(5) A new instrumentation for posterior spinal surgery consists of metallic rods carved with diamond-shaped asperities on which vertebral hooks or screws can be screwed in any position, level, or degree of rotation.
(6) Conditions that inhibited phospholipase A2 activity, i.e., substitution of calcium by EDTA, reduced liposome-disrupting activity of Bothrops asper myotoxin I and Bothrops atrox myotoxin, both of which have high phospholipase A2 activity, but did not affect the action of B. asper myotoxin II and Bothrops moojeni myotoxin II, which have extremely low phospholipase A2 activity.
(7) The time-course and composition of inflammatory infiltrate in mouse gastrocnemius injected with Bothrops asper venom was studied.
(8) Also, the organization of these asperities is directly related to cellular cytoskeletal elements.
(9) The neutralization of two myotoxic phospholipases A2 from the venom of Bothrops asper, myotoxins I and II, by two murine monoclonal antibodies is reported.
(10) Seventeen batches of ICP antivenom were analyzed by EIA, using B. asper myotoxin II as antigen.
(11) No major differences in the DNase electrophoretic pattern were observed between individual venoms of adult B. asper specimens nor between lyophilized and frozen venoms.
(12) It is suggested that muscle regeneration is partially impaired after myonecrosis induced by Bothrops asper venom, probably due to the damage induced by this venom on muscle microvasculature and nerves.
(13) He used fine needle asperation or scraping of pathological tissue and hematoxylin-eosin staining of smears.
(14) Immunochemical results indicate a close immunological relationship between venoms of B. asper, B. nummifer and C. d. durissus collected in Honduras and Guatemala with those of the same species collected in Costa Rica.
(15) A new muscle damaging toxin, myotoxin II, was purified from the venom of Bothrops asper by ion-exchange chromatography on CM-Sephadex C-25.
(16) Ouchterlony immunodiffusion analysis of purified antibodies showed two precipitation bands with a pattern of complete immunologic identity between samples of crude B. asper venoms from specimens collected in the Atlantic and Pacific regions of Costa Rica.
(17) Myotoxin is an abundant component in adult B. asper venom.
(18) Five polyvalent antivenoms (Crotalidae; Orient, North, Central and South Africa) were tested for their ability to neutralize the thrombin-like activity of snake venoms (Bitis gabonica, Agkistrodon acutus, Bothrops asper, B. atrox, Crotalus adamanteus).
(19) A myotoxic, basic phospholipase A2 (pI greater than 9.5) with anticoagulant activity has been purified from the venom of Bothrops asper, and its amino acid sequence determined by automated Edman degradation.
(20) The effects of a myotoxic phospholipase A2 isolated from the venom of the crotaline snake Bothrops asper on skeletal muscle myofibrils were studied by histological, ultrastructural, immunohistochemical, and biochemical parameters.