(1) A sensitive and specific reversed-phase high-performance liquid chromatography (HPLC) method is described for the quantitative determination of albendazole sulfoxide (ASOX); since albendazole sulfone (ASON) appears only in small amounts and albendazole (ABZ) normally does not appear in human plasma, only a qualitative determination of ASON and ABZ was made in human plasma.
(2) Calibration was linear in a concentration range of 0.05-12 microM for ASOX and 0.1-8 microM for ASON, respectively.
(3) The detection limit of the main metabolite ASOX was 50 nM and that of ASON was 100 nM.
Sonant
Definition:
(a.) Of or pertaining to sound; sounding.
(a.) Uttered, as an element of speech, with tone or proper vocal sound, as distinguished from mere breath sound; intonated; voiced; tonic; the opposite of nonvocal, or surd; -- sid of the vowels, semivowels, liquids, and nasals, and particularly of the consonants b, d, g hard, v, etc., as compared with their cognates p, t, k, f, etc., which are called nonvocal, surd, or aspirate.
(n.) A sonant letter.
Example Sentences:
(1) Now, when the Bristol Pound emerges , or when the business-to-business currency SoNantes is introduced for the businesses around the French city of Nantes, commissioned by a former mayor and former French prime minister Jean-Marc Ayrault, the idea gains further weight for sustainable economic development, rather than just for crisis mitigation.
(2) The city of Nantes in France just launched the SoNantes as an way to support SMEs in the region.