(n.) Roughness of surface; unevenness; -- opposed to smoothness.
(n.) Roughness or harshness of sound; that quality which grates upon the ear; raucity.
(n.) Roughness to the taste; sourness; tartness.
(n.) Moral roughness; roughness of manner; severity; crabbedness; harshness; -- opposed to mildness.
(n.) Sharpness; disagreeableness; difficulty.
Example Sentences:
(1) The presence of proteins antigenically related to Bothrops asper myotoxins in various snake venoms, mainly from South America, was investigated by using polyclonal and monoclonal antibodies.
(2) The myotoxin shows partial immunologic identity with a myotoxic phospholipase A2 isolated from Bothrops asper venom.
(3) Mice that received antivenom (0.4 ml) by the iv or im route 15 min after im injection of B. asper venom (100 micrograms) had lower levels of plasma anti-myotoxin antibodies than controls injected with antivenom only, suggesting that at least a fraction of the antibodies combines with myotoxins in vivo.
(4) Metalloproteinase from the venom of Bothrops asper (proteinase G) is a glycoprotein with 1% neutral hexose and 3.5 moles of sialic acid per mole of protein.
(5) A new instrumentation for posterior spinal surgery consists of metallic rods carved with diamond-shaped asperities on which vertebral hooks or screws can be screwed in any position, level, or degree of rotation.
(6) Conditions that inhibited phospholipase A2 activity, i.e., substitution of calcium by EDTA, reduced liposome-disrupting activity of Bothrops asper myotoxin I and Bothrops atrox myotoxin, both of which have high phospholipase A2 activity, but did not affect the action of B. asper myotoxin II and Bothrops moojeni myotoxin II, which have extremely low phospholipase A2 activity.
(7) The time-course and composition of inflammatory infiltrate in mouse gastrocnemius injected with Bothrops asper venom was studied.
(8) Also, the organization of these asperities is directly related to cellular cytoskeletal elements.
(9) The neutralization of two myotoxic phospholipases A2 from the venom of Bothrops asper, myotoxins I and II, by two murine monoclonal antibodies is reported.
(10) Seventeen batches of ICP antivenom were analyzed by EIA, using B. asper myotoxin II as antigen.
(11) No major differences in the DNase electrophoretic pattern were observed between individual venoms of adult B. asper specimens nor between lyophilized and frozen venoms.
(12) It is suggested that muscle regeneration is partially impaired after myonecrosis induced by Bothrops asper venom, probably due to the damage induced by this venom on muscle microvasculature and nerves.
(13) He used fine needle asperation or scraping of pathological tissue and hematoxylin-eosin staining of smears.
(14) Immunochemical results indicate a close immunological relationship between venoms of B. asper, B. nummifer and C. d. durissus collected in Honduras and Guatemala with those of the same species collected in Costa Rica.
(15) A new muscle damaging toxin, myotoxin II, was purified from the venom of Bothrops asper by ion-exchange chromatography on CM-Sephadex C-25.
(16) Ouchterlony immunodiffusion analysis of purified antibodies showed two precipitation bands with a pattern of complete immunologic identity between samples of crude B. asper venoms from specimens collected in the Atlantic and Pacific regions of Costa Rica.
(17) Myotoxin is an abundant component in adult B. asper venom.
(18) Five polyvalent antivenoms (Crotalidae; Orient, North, Central and South Africa) were tested for their ability to neutralize the thrombin-like activity of snake venoms (Bitis gabonica, Agkistrodon acutus, Bothrops asper, B. atrox, Crotalus adamanteus).
(19) A myotoxic, basic phospholipase A2 (pI greater than 9.5) with anticoagulant activity has been purified from the venom of Bothrops asper, and its amino acid sequence determined by automated Edman degradation.
(20) The effects of a myotoxic phospholipase A2 isolated from the venom of the crotaline snake Bothrops asper on skeletal muscle myofibrils were studied by histological, ultrastructural, immunohistochemical, and biochemical parameters.
Austere
Definition:
() Sour and astringent; rough to the state; having acerbity; as, an austere crab apple; austere wine.
() Severe in modes of judging, or living, or acting; rigid; rigorous; stern; as, an austere man, look, life.
() Unadorned; unembellished; severely simple.
Example Sentences:
(1) Since the start of this week, markets have been more cautious, with bond yields in Spain reaching their highest levels in four months on Tuesday amid concern about the scale of the austerity measures being imposed by the government and fears that the country might need a bailout.
(2) In a separate exclusive interview , Alexis Tsipras, the increasingly powerful 37-year-old Greek politician now regarded by many as holding the future of the euro in his hands, told the Guardian that he was determined "to stop the experiment" with austerity policies imposed by Germany.
(3) He campaigned for a no vote and won handsomely, backed by more than 61%, before performing a striking U-turn on Thursday night, re-tabling the same austerity terms he had campaigned to defeat and which the voters rejected.
(4) But that promise was beginning to startle the markets, which admire Monti’s appetite for austerity and fear the free spending and anti-European views of some Italian politicians.
(5) Cable argued that the additional £30bn austerity proposed by the chancellor after 2015 went beyond the joint coalition commitment to eradicate the structural part of the UK's current budget deficit – the part of non-investment spending that will not disappear even when the economy has fully emerged from the recession of 2008-09.
(6) All of the parties have been trying to use Greece to their advantage.” On Monday, the governing People’s party pointed to the referendum to justify their decision to impose austerity measures during the height of the economic crisis.
(7) Greece sincerely had no intention of clashing with its partners, Varoufakis insisted, but the logic of austerity was such that policies conducted in its embrace could only fail.
(8) As Greece pleads with its eurozone creditors for more time in meeting its fiscal adjustment targets, Dombrovskis is a fierce champion of surgical austerity applied quickly and ruthlessly.
(9) Updated at 12.23pm BST 12.04pm BST As Mariano Rajoy and François Hollande prepare to reveal their austerity budgets (Spain goes on Thursday and France on Friday), they might be forgiven for casting an envious eye towards Australia where government statisticians revealed that the country is A$325bn (£200bn) better off than they'd thought.
(10) This proposal is a purely partisan move that will backfire on the government disastrously.” The Green party accused Osborne of making “efforts to limit the democratic scrutiny of his austerity agenda”.
(11) The budget red book contained a chart which suggested that the rich were indeed facing a bigger hit than anyone else, and Liberal Democrats were today pointing to this to justify the austerity package.
(12) "But if public opposition to further austerity measures hardens, the Greek government could find it even tougher to put the public finances back on a sustainable footing."
(13) The austerity programmes administered by western governments in the wake of the 2008 global financial crisis were, of course, intended as a remedy, a tough but necessary course of treatment to relieve the symptoms of debts and deficits and to cure recession.
(14) In the midst of this catastrophe, the troika is insisting on further austerity to achieve massive primary budget surpluses of 3% in 2015, 4.5% in 2016 and even more in future years.
(15) In a Europe (including Britain) where austerity has become the economic dogma of the elite in spite of massive evidence that it is choking growth and worsening the very sickness it claims to heal, there are plenty of rational, sensible arguments for taking to the streets.
(16) The Attlee government was toppled by peacetime austerity that voters no longer trusted.
(17) After heading for Rome with his long-term partner, Howard Auster, he returned to fiction with a bestselling novel, Julian, based on the life of a late Roman emperor; a political novel, Washington DC, based on his own family; and Myra Breckinridge, a subversive satire that examined contradictions of gender and sexuality with enough comic brio to become a worldwide bestseller.
(18) Yesterday, John McDonnell spelled out the new Labour leadership’s public investment-driven economic alternative to austerity.
(19) Then Greece has another chance.” But the intervention by the IMF will undermine EU leaders who argue Greece must submit to a fresh round of austerity measures to release funds for debt repayments.
(20) The IMF itself came under fire after it admitted in its World Economic Outlook report that officials had underestimated the effects of austerity measures on economic growth.