(n.) Roughness of surface; unevenness; -- opposed to smoothness.
(n.) Roughness or harshness of sound; that quality which grates upon the ear; raucity.
(n.) Roughness to the taste; sourness; tartness.
(n.) Moral roughness; roughness of manner; severity; crabbedness; harshness; -- opposed to mildness.
(n.) Sharpness; disagreeableness; difficulty.
Example Sentences:
(1) The presence of proteins antigenically related to Bothrops asper myotoxins in various snake venoms, mainly from South America, was investigated by using polyclonal and monoclonal antibodies.
(2) The myotoxin shows partial immunologic identity with a myotoxic phospholipase A2 isolated from Bothrops asper venom.
(3) Mice that received antivenom (0.4 ml) by the iv or im route 15 min after im injection of B. asper venom (100 micrograms) had lower levels of plasma anti-myotoxin antibodies than controls injected with antivenom only, suggesting that at least a fraction of the antibodies combines with myotoxins in vivo.
(4) Metalloproteinase from the venom of Bothrops asper (proteinase G) is a glycoprotein with 1% neutral hexose and 3.5 moles of sialic acid per mole of protein.
(5) A new instrumentation for posterior spinal surgery consists of metallic rods carved with diamond-shaped asperities on which vertebral hooks or screws can be screwed in any position, level, or degree of rotation.
(6) Conditions that inhibited phospholipase A2 activity, i.e., substitution of calcium by EDTA, reduced liposome-disrupting activity of Bothrops asper myotoxin I and Bothrops atrox myotoxin, both of which have high phospholipase A2 activity, but did not affect the action of B. asper myotoxin II and Bothrops moojeni myotoxin II, which have extremely low phospholipase A2 activity.
(7) The time-course and composition of inflammatory infiltrate in mouse gastrocnemius injected with Bothrops asper venom was studied.
(8) Also, the organization of these asperities is directly related to cellular cytoskeletal elements.
(9) The neutralization of two myotoxic phospholipases A2 from the venom of Bothrops asper, myotoxins I and II, by two murine monoclonal antibodies is reported.
(10) Seventeen batches of ICP antivenom were analyzed by EIA, using B. asper myotoxin II as antigen.
(11) No major differences in the DNase electrophoretic pattern were observed between individual venoms of adult B. asper specimens nor between lyophilized and frozen venoms.
(12) It is suggested that muscle regeneration is partially impaired after myonecrosis induced by Bothrops asper venom, probably due to the damage induced by this venom on muscle microvasculature and nerves.
(13) He used fine needle asperation or scraping of pathological tissue and hematoxylin-eosin staining of smears.
(14) Immunochemical results indicate a close immunological relationship between venoms of B. asper, B. nummifer and C. d. durissus collected in Honduras and Guatemala with those of the same species collected in Costa Rica.
(15) A new muscle damaging toxin, myotoxin II, was purified from the venom of Bothrops asper by ion-exchange chromatography on CM-Sephadex C-25.
(16) Ouchterlony immunodiffusion analysis of purified antibodies showed two precipitation bands with a pattern of complete immunologic identity between samples of crude B. asper venoms from specimens collected in the Atlantic and Pacific regions of Costa Rica.
(17) Myotoxin is an abundant component in adult B. asper venom.
(18) Five polyvalent antivenoms (Crotalidae; Orient, North, Central and South Africa) were tested for their ability to neutralize the thrombin-like activity of snake venoms (Bitis gabonica, Agkistrodon acutus, Bothrops asper, B. atrox, Crotalus adamanteus).
(19) A myotoxic, basic phospholipase A2 (pI greater than 9.5) with anticoagulant activity has been purified from the venom of Bothrops asper, and its amino acid sequence determined by automated Edman degradation.
(20) The effects of a myotoxic phospholipase A2 isolated from the venom of the crotaline snake Bothrops asper on skeletal muscle myofibrils were studied by histological, ultrastructural, immunohistochemical, and biochemical parameters.
Endure
Definition:
(v. i.) To continue in the same state without perishing; to last; to remain.
(v. i.) To remain firm, as under trial or suffering; to suffer patiently or without yielding; to bear up under adversity; to hold out.
(v. t.) To remain firm under; to sustain; to undergo; to support without breaking or yielding; as, metals endure a certain degree of heat without melting; to endure wind and weather.
(v. t.) To bear with patience; to suffer without opposition or without sinking under the pressure or affliction; to bear up under; to put up with; to tolerate.
(v. t.) To harden; to toughen; to make hardy.
Example Sentences:
(1) Patients had improved sitting balance and endurance after surgery.
(2) There was no significant correlation between mitochondrial volume and number of SO fibers following endurance exercise training.
(3) Thus it appears that a portion of the adaptation to prolonged and intense endurance training that is responsible for the higher lactate threshold in the trained state persists for a long time (greater than 85 days) after training is stopped.
(4) Her novels have an enduring and universal appeal and she is recognised as one of the greatest writers in English literature.
(5) Respiratory muscle endurance at a given level of load was assessed from the time of exhaustion and from the time course of the change in the power spectrum (centroid frequency) of the diaphragm electromyogram (EMG).
(6) The investigation included the measurement of heart rate, bioelectrical muscle activity of the right and left M. biceps brachii and M. deltoideus and muscular endurance at 50% MVC.
(7) First, the decrement in the maximal heart rate response to exercise (known as "chronotropic incompetence") found in the sedentary MI rat was completely reversed by endurance training.
(8) Collins later thanked the condemned man for what he said was the respect he showed toward the execution team and for the way he endured the ordeal.
(9) There were discrete linear relationships between muscle temperature and isometric endurance associated with cycling at 60% and 80% VO2max.
(10) Endurance times with the vest were 300 min (175 W) and 242-300 min (315 W).
(11) Because the changes of the arterial blood lactate (Laa) and VE coincide we defined this point as the "point of the optimal ventilatory efficiency," identical with the "O2 endurance performance limit," later called "anaerobic threshold" by Wasserman et al.
(12) Zuma, who had endured booing during Mandela's memorial service at this stadium, received a rapturous welcome as he entered to the sound of a military drumroll trailed by young, flag-waving majorettes.
(13) In multiple regression analysis of endurance capacity, the standardized regression coefficient for smoking was -0.14 for distance covered in the 12-min run and 0.10 for 16-km running time, the latter despite the low prevalence (6.9%) of regular cigarette smokers among the joggers.
(14) I think that those who go there, to Isis, they hate Russia for the conditions they have to endure to live,” Nazarov’s brother says.
(15) These results indicate that the increase in glucose storage by acute exercise is not systematically associated with an improved glucose homeostasis, suggesting that other adaptive mechanisms also contribute to the improvement of insulin sensitivity in endurance athletes.
(16) Nine mild to moderate asthmatic adults (three males, six females) and six non-asthmatics (one male, five females) underwent endurance running training three times per week for five weeks, at self selected running speeds on a motorized treadmill.
(17) But to endure a cut of £100m just after becoming the mayor and a further £23m this year has been daunting.
(18) Further, to study the effect of endurance training on this response, animals from each age group underwent ten weeks of treadmill running at 75% of their functional capacity.
(19) Already much work has been done to re-establish enduring components for Labour's electoral success: clarity of strategy, effective rebuttal, and superior field organisation with our network of community organisers.
(20) As expected, preexercise values of non-trained subjects revealed a much higher insulin response to glucose, and a lower glucose storage and lipid oxidation compared to results obtained in endurance trained individuals.