What's the difference between asperity and grimness?
Asperity
Definition:
(n.) Roughness of surface; unevenness; -- opposed to smoothness.
(n.) Roughness or harshness of sound; that quality which grates upon the ear; raucity.
(n.) Roughness to the taste; sourness; tartness.
(n.) Moral roughness; roughness of manner; severity; crabbedness; harshness; -- opposed to mildness.
(n.) Sharpness; disagreeableness; difficulty.
Example Sentences:
(1) The presence of proteins antigenically related to Bothrops asper myotoxins in various snake venoms, mainly from South America, was investigated by using polyclonal and monoclonal antibodies.
(2) The myotoxin shows partial immunologic identity with a myotoxic phospholipase A2 isolated from Bothrops asper venom.
(3) Mice that received antivenom (0.4 ml) by the iv or im route 15 min after im injection of B. asper venom (100 micrograms) had lower levels of plasma anti-myotoxin antibodies than controls injected with antivenom only, suggesting that at least a fraction of the antibodies combines with myotoxins in vivo.
(4) Metalloproteinase from the venom of Bothrops asper (proteinase G) is a glycoprotein with 1% neutral hexose and 3.5 moles of sialic acid per mole of protein.
(5) A new instrumentation for posterior spinal surgery consists of metallic rods carved with diamond-shaped asperities on which vertebral hooks or screws can be screwed in any position, level, or degree of rotation.
(6) Conditions that inhibited phospholipase A2 activity, i.e., substitution of calcium by EDTA, reduced liposome-disrupting activity of Bothrops asper myotoxin I and Bothrops atrox myotoxin, both of which have high phospholipase A2 activity, but did not affect the action of B. asper myotoxin II and Bothrops moojeni myotoxin II, which have extremely low phospholipase A2 activity.
(7) The time-course and composition of inflammatory infiltrate in mouse gastrocnemius injected with Bothrops asper venom was studied.
(8) Also, the organization of these asperities is directly related to cellular cytoskeletal elements.
(9) The neutralization of two myotoxic phospholipases A2 from the venom of Bothrops asper, myotoxins I and II, by two murine monoclonal antibodies is reported.
(10) Seventeen batches of ICP antivenom were analyzed by EIA, using B. asper myotoxin II as antigen.
(11) No major differences in the DNase electrophoretic pattern were observed between individual venoms of adult B. asper specimens nor between lyophilized and frozen venoms.
(12) It is suggested that muscle regeneration is partially impaired after myonecrosis induced by Bothrops asper venom, probably due to the damage induced by this venom on muscle microvasculature and nerves.
(13) He used fine needle asperation or scraping of pathological tissue and hematoxylin-eosin staining of smears.
(14) Immunochemical results indicate a close immunological relationship between venoms of B. asper, B. nummifer and C. d. durissus collected in Honduras and Guatemala with those of the same species collected in Costa Rica.
(15) A new muscle damaging toxin, myotoxin II, was purified from the venom of Bothrops asper by ion-exchange chromatography on CM-Sephadex C-25.
(16) Ouchterlony immunodiffusion analysis of purified antibodies showed two precipitation bands with a pattern of complete immunologic identity between samples of crude B. asper venoms from specimens collected in the Atlantic and Pacific regions of Costa Rica.
(17) Myotoxin is an abundant component in adult B. asper venom.
(18) Five polyvalent antivenoms (Crotalidae; Orient, North, Central and South Africa) were tested for their ability to neutralize the thrombin-like activity of snake venoms (Bitis gabonica, Agkistrodon acutus, Bothrops asper, B. atrox, Crotalus adamanteus).
(19) A myotoxic, basic phospholipase A2 (pI greater than 9.5) with anticoagulant activity has been purified from the venom of Bothrops asper, and its amino acid sequence determined by automated Edman degradation.
(20) The effects of a myotoxic phospholipase A2 isolated from the venom of the crotaline snake Bothrops asper on skeletal muscle myofibrils were studied by histological, ultrastructural, immunohistochemical, and biochemical parameters.
Grimness
Definition:
(n.) Fierceness of look; sternness; crabbedness; forbiddingness.
Example Sentences:
(1) This is the grim Fury on a rainy winter morning in Cannes.
(2) The level of prescribing of opioid painkillers – Percocet in Geni’s case – has soared, and with it the incidence of addiction, and addiction’s grim best friend: fatal overdoses.
(3) Patients with anti-NC1 antibodies were characterised by linear immune deposits along the glomerular basement membrane and the clinical outcome was invariably grim.
(4) The Mail branded the deal "a grim day for all who value freedom" and, like the Times, accused David Cameron of crossing the Rubicon and threatening press freedom for the first time since newspapers were licensed in the 17th century.
(5) ARD TV showing grim-faced FDP cadres: could this be the first time they fall out of national parliament in 60 years?
(6) It has said a better productivity performance and rising North Sea oil revenues will make the budgetary position less grim.
(7) Shields accepted that the Irish appeared more inclined to send up their grim fiscal situation than go out and riot.
(8) Inside the Islamic State ‘capital’: no end in sight to its grim rule Read more The Kurdish People’s Protection Units (YPG) militia and an alliance of rebels known as the “Euphrates Volcano” – backed US-led coalition air strikes – have seized swaths of territory from Isis, including the strategic border town of Tal Abyad .
(9) Yet, if that flurry of form pepped optimism, the injuries and displays in recent friendlies have provided a grim reality check.
(10) The dark, luxury air in the silent bedrooms of empty riverside apartments, their identical curving blocks clustered in threes and fours, grim and silent as gill slits, will be theirs.
(11) Chinese media and bloggers published images of three young children in blue school uniforms lying dead on the pavement – a grim echo of the high casualty rate at poorly constructed schools in Sichuan in 2008, when a bigger quake killed 87,000 people.
(12) The BCC survey represents a turnround from the end of last year, when it was predicting stagflation – a grim combination of zero growth and inflation.
(13) The human rights organisation, which has produced a series of in-depth reports detailing the grim working conditions of many of the 1.5 million migrant labourers engaged in a huge construction boom, said “little has changed in law, policy and practice” since the government promised limited reforms 12 months ago.
(14) Carcinoma of unknown histogenesis or primary site is an increasingly recognized syndrome regarded by most physicians as having a grim prognosis.
(15) "There are times when a swingeing sentence can act as a deterrent", as the judge at the trial was grimly to pronounce.
(16) The footage beamed back from the liberated districts of Ramadi is grim: a ghost town littered with debris and smashed concrete, destroyed storefronts, plumes of smoke, the sound of gunfire piercing the air as Iraqi soldiers speak on camera.
(17) It was my shortcomings as coach that caused this result,” said a grim-faced South Korea manager, Hong Myung-bo, who spent most of the post-match press-conference scratching his nose in apparent distress and deflecting comments about whether he would stay on as manager until next year’s Asian Cup.
(18) After grim news on the recession, at least one thing should become clearer: going back to where we were is no longer an option.
(19) While deplorable and to a degree self-defeating, this insouciant defiance also makes a grim kind of sense, both historically and reinforced by recent events.
(20) The entity carries a grim visual prognosis, as all ten eyes initially had no perception of light; improvement to light perception occurred in one instance.