(n.) Roughness of surface; unevenness; -- opposed to smoothness.
(n.) Roughness or harshness of sound; that quality which grates upon the ear; raucity.
(n.) Roughness to the taste; sourness; tartness.
(n.) Moral roughness; roughness of manner; severity; crabbedness; harshness; -- opposed to mildness.
(n.) Sharpness; disagreeableness; difficulty.
Example Sentences:
(1) The presence of proteins antigenically related to Bothrops asper myotoxins in various snake venoms, mainly from South America, was investigated by using polyclonal and monoclonal antibodies.
(2) The myotoxin shows partial immunologic identity with a myotoxic phospholipase A2 isolated from Bothrops asper venom.
(3) Mice that received antivenom (0.4 ml) by the iv or im route 15 min after im injection of B. asper venom (100 micrograms) had lower levels of plasma anti-myotoxin antibodies than controls injected with antivenom only, suggesting that at least a fraction of the antibodies combines with myotoxins in vivo.
(4) Metalloproteinase from the venom of Bothrops asper (proteinase G) is a glycoprotein with 1% neutral hexose and 3.5 moles of sialic acid per mole of protein.
(5) A new instrumentation for posterior spinal surgery consists of metallic rods carved with diamond-shaped asperities on which vertebral hooks or screws can be screwed in any position, level, or degree of rotation.
(6) Conditions that inhibited phospholipase A2 activity, i.e., substitution of calcium by EDTA, reduced liposome-disrupting activity of Bothrops asper myotoxin I and Bothrops atrox myotoxin, both of which have high phospholipase A2 activity, but did not affect the action of B. asper myotoxin II and Bothrops moojeni myotoxin II, which have extremely low phospholipase A2 activity.
(7) The time-course and composition of inflammatory infiltrate in mouse gastrocnemius injected with Bothrops asper venom was studied.
(8) Also, the organization of these asperities is directly related to cellular cytoskeletal elements.
(9) The neutralization of two myotoxic phospholipases A2 from the venom of Bothrops asper, myotoxins I and II, by two murine monoclonal antibodies is reported.
(10) Seventeen batches of ICP antivenom were analyzed by EIA, using B. asper myotoxin II as antigen.
(11) No major differences in the DNase electrophoretic pattern were observed between individual venoms of adult B. asper specimens nor between lyophilized and frozen venoms.
(12) It is suggested that muscle regeneration is partially impaired after myonecrosis induced by Bothrops asper venom, probably due to the damage induced by this venom on muscle microvasculature and nerves.
(13) He used fine needle asperation or scraping of pathological tissue and hematoxylin-eosin staining of smears.
(14) Immunochemical results indicate a close immunological relationship between venoms of B. asper, B. nummifer and C. d. durissus collected in Honduras and Guatemala with those of the same species collected in Costa Rica.
(15) A new muscle damaging toxin, myotoxin II, was purified from the venom of Bothrops asper by ion-exchange chromatography on CM-Sephadex C-25.
(16) Ouchterlony immunodiffusion analysis of purified antibodies showed two precipitation bands with a pattern of complete immunologic identity between samples of crude B. asper venoms from specimens collected in the Atlantic and Pacific regions of Costa Rica.
(17) Myotoxin is an abundant component in adult B. asper venom.
(18) Five polyvalent antivenoms (Crotalidae; Orient, North, Central and South Africa) were tested for their ability to neutralize the thrombin-like activity of snake venoms (Bitis gabonica, Agkistrodon acutus, Bothrops asper, B. atrox, Crotalus adamanteus).
(19) A myotoxic, basic phospholipase A2 (pI greater than 9.5) with anticoagulant activity has been purified from the venom of Bothrops asper, and its amino acid sequence determined by automated Edman degradation.
(20) The effects of a myotoxic phospholipase A2 isolated from the venom of the crotaline snake Bothrops asper on skeletal muscle myofibrils were studied by histological, ultrastructural, immunohistochemical, and biochemical parameters.
Sarcastic
Definition:
(a.) Alt. of Sarcastical
Example Sentences:
(1) As Robert Vittek put Slovakia 5-1 ahead on 59 minutes, hundreds were heading for the exits while many of the remaining fans sarcastically cheered the most routine saves from their goalkeeper.
(2) Persepolis , the Greek name for Persia, is desperately moving and extremely funny - a little girl's sarcastic love letter to her family.
(3) "When you read the book, he sounds more sarcastic and snarky, closer to Holden Caulfield ," he says, "but with Dustin Hoffman it feels genuinely rabbit-in-the-headlights."
(4) Now, though, the staycationers are coming and the donkeys are less sarcastic.
(5) There's nothing defensive or snippy or sarcastic about his tone when he tells you that he can't act, or carries on as if his entire professional life is a kind of complicated mistake: he's actually rather charming company.
(6) "There's the side that wants to go along with it, but there's also a very sarcastic, sceptical side."
(7) They make sarcastic remarks about Reader being a so- called “master criminal”.
(8) "Here are the internet terrorists," their lawyer Rémy Josseaume sarcastically told the court in the southern town of Rodez on Tuesday.
(9) He does not have experience but he has potential.” Mourinho had a sarcastic comment for Fifa, after hearing that the governing body had made a statement about the on-going fallout from Mohamed Salah’s season-long loan move to Roma.
(10) It grinds us down until we adopt a worldview that is pessimistic, desensitised, sarcastic and fatalistic.
(11) From the opening lines of Vietnam, Grant's set was sad, funny, tortured, sarcastic and, frankly, pure bloody perfection.
(12) That match too had its moments – notably when the Serb made a sarcastic racket-slap in response to the crowd’s cheer for a double fault that led to a break in a sloppy second set.
(13) The Chelsea manager, José Mourinho , has been fined after his sarcastic appraisal of officials following the defeat by Sunderland.
(14) But what Clegg's rightwing and leftwing critics miss, as do predictably sarcastic journalists, is that this is precisely the point.
(15) Or as CBS Sports' Zach Harper sarcastically noted : "Can't wait for that nationally televised Heat-Bobcats game coming up."
(16) He said Christie laughed and made a sarcastic joke when he learned of Sokolich’s distress over not getting his calls returned.
(17) Countering that complaint Israel’s UN ambassador, Ron Prosor, sent what the Israeli mission called a “sarcastic letter” to the security council listing acts of incitement by the Palestinian leadership, including last month’s drive-by shooting of a Jewish activist who had pushed for greater Jewish access to the sacred hilltop compound.
(18) The Valencia reporter for Onda Cero radio called it a “lack of respect”, while in AS it was described sarcastically as “English humour”.
(19) Not only did it get a sarcastic jeer from the Tories, but it made Vince ratty.
(20) Here's where I should warn readers that I may sometimes be sarcastic.