What's the difference between association and linkage?

Association


Definition:

  • (n.) The act of associating, or state of being associated; union; connection, whether of persons of things.
  • (n.) Mental connection, or that which is mentally linked or associated with a thing.
  • (n.) Union of persons in a company or society for some particular purpose; as, the American Association for the Advancement of Science; a benevolent association. Specifically, as among the Congregationalists, a society, consisting of a number of ministers, generally the pastors of neighboring churches, united for promoting the interests of religion and the harmony of the churches.

Example Sentences:

  • (1) All mutant proteins could associate with troponin I and troponin T to form a troponin complex.
  • (2) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
  • (3) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
  • (4) Perinatal mortality is strongly associated with obstetrical factors, respiratory distress syndrome, and prematurity.
  • (5) We also show that proliferation of primary amnion cells is not dependent on a high c-fos expression, suggesting that the function of c-fos is more likely to be associated with other cellular functions in the differentiated amnion cell.
  • (6) Increased plasmin activity was associated with advancing stage of lactation and older cows after appropriate adjustments were made for the effects of milk yield and SCC.
  • (7) We propose that this dependence on coexpression reflects the association between the LTA::STa hybrids and LTB subunits.
  • (8) Weddellite calcification was associated with benign lesions in 16 cases, but incidental atypical lobular hyperplasia and lobular carcinoma in situ were present, each in one case.
  • (9) The fraction of the viral dose which became cell associated was independent of the incubation temperature and increased with increasing target membrane concentration.
  • (10) Together these results suggest that IVC may operate as a selective activator of calpain both in the cytosol and at the membrane level; in the latter case in synergism with the activation induced by association of the proteinase to the cell membrane.
  • (11) The combined analysis of pathogenesis and genetics associated with the salmonella virulence plasmids may identify new systems of bacterial virulence and the genetic basis for this virulence.
  • (12) Histological studies showed that the resulting pancreatitis was usually mild to moderate, being severe only in association with sepsis.
  • (13) Meanwhile the efficiency of muscarinic antagonists in inhibition of tremor reaction induced by arecoline administration is associated with interaction between the drugs and the M2-subtype.
  • (14) Biden will meet with representatives from six gun groups on Thursday, including the NRA and the Independent Firearms Owners Association, which are both publicly opposed to stricter gun-control laws.
  • (15) This clinical improvement was also associated with a decrease of erythrocyte sedimentation rate (p less than 0.001), decrease of C-reactive protein (p less than 0.0001) and with improvement of anaemia (p less than 0.05).
  • (16) Some of those drugs are able to stimulate the macrophages, even in an aspecific way, via the gut associated lymphatic tissue (GALT), that is in connection with the bronchial associated lymphatic tissue (BALT).
  • (17) Most of the radioactivity in spleen cells from these rats were associated with antigen-reactive cells which formed rosettes specifically with HO erythrocytes.
  • (18) The findings suggest that these two syndromes are associated with dysfunction at two different sites within the frontal lobes.
  • (19) The strongest predictor of non-sudden cardiac death was the New York Heart Association functional class.
  • (20) Male sex, age under 19 or over 45, few social supports, and a history of previous suicide attempts are all factors associated with increased suicide rates.

Linkage


Definition:

  • (n.) The act of linking; the state of being linked; also, a system of links.
  • (n.) Manner of linking or of being linked; -- said of the union of atoms or radicals in the molecule.
  • (n.) A system of straight lines or bars, fastened together by joints, and having certain of their points fixed in a plane. It is used to describe straight lines and curves in the plane.

Example Sentences:

  • (1) The presence of O-glycosidic linkages between carbohydrate and protein in the DF3 antigenic site was further supported by the presence of NaBH4-sensitive sites.
  • (2) Twelve families with Wiskott-Aldrich syndrome (WAS) were studied by linkage analysis using 10 polymorphic marker loci from the X-chromosome pericentromeric region.
  • (3) A complex linkage between the cytoskeleton and the extracellular matrix is illustrated both in the cord forming Sertoli and granulosa cells, and in the adjacent mesenchymal cells.
  • (4) The assumption was also corroborated using reagents from a family in which DR3 and DQw2 were not found in the usually described linkage.
  • (5) This linkage information was used to design complementation tests to determine allelism with previously characterized complementation groups affecting sensitivity to radiation.
  • (6) Sensitivity and specificity were enhanced when we linked multiple predictors, but this linkage was seldom successful because few patients had more than one positive predictor.
  • (7) Analysis of the product by equilibrium density centrifugation and processive hydrolysis with snake venom phosphodiesterase suggested that the noncomplementary nucleotides were present in phosphodiester linkage.
  • (8) The same segments have been described to be responsible for the hexamer-hexamer linkage (Yu, M.-H. & Glazer, A.N.
  • (9) The two disorders may associate within families through genetic linkage or a failure of neurotransmitter homoeostasis.
  • (10) Isopycnic analyses of the ribonucleotide initiated fd DNA replication products demonstrated covalent linkage between the initiator RNA and newly synthesized DNA.
  • (11) The others had the structures galactosyl-galactosyl-xylosyl-4-methylumbelliferone and galactosyl-xylosyl-4-methylumbelliferone, respectively, representing the linkage region between the glycosaminoglycan chains and core protein, except that 4-methylumbelliferone replaced the amino acid.
  • (12) Absence of linkage in a large group of families shows that lamp genes are not involved in Salla disease.
  • (13) Because each linkage project is different, the modular nature of the software allows for better control of the programming process and development of unique strategies.
  • (14) Family clustering suggests a genetic pathogenesis, but linkage to HLA or other blood group markers has not been found.
  • (15) Biosynthesis of the two N-glycosyl linkage units involves dolichol monophosphate and dolicholdiphosphate-linked saccharide precursors.
  • (16) In addition, the distances between markers in the mouse and human were similar except for one region of the conserved linkage group where we could detect a larger distance in the mouse compared to the human.
  • (17) The inter-connecting linkage system develops postnatally, and the 'tip-linkages' are already found in one-week-old mice, suggesting that the critical organization of the micromechanics of the stereocilia matures rapidly during the postnatal period.
  • (18) Using molecular probes to examine somatic cell lines and recombinant inbred and congenic strains of mice, we have re-evaluated these linkage relationships.
  • (19) We now report linkage between CF and pJ3.11 (Z = 4.92, theta = 0) and between CF and 7C22 (Z = 3.42, theta = 0).
  • (20) Recently, a gene for ITD (DYT1) in a non-Jewish kindred was located on chromosome 9q32-34, with tight linkage to the gene encoding gelsolin (GSN).