(n.) A disease, characterized by difficulty of breathing (due to a spasmodic contraction of the bronchi), recurring at intervals, accompanied with a wheezing sound, a sense of constriction in the chest, a cough, and expectoration.
Example Sentences:
(1) Until the 1960's there was great confusion, both within and between countries, on the meaning of diagnostic terms such as emphysema, asthma, and chronic brochitis.
(2) 278 children with bronchial asthma were medically, socially and psychologically compared to 27 rheumatic and 19 diabetic children.
(3) Asthma is probably the commonest chronic disease in the United Kingdom, and its attendant morbidity extends outside the possible scope of the hospital sector.
(4) The asthma group's fall in FEV1 was also abolished.
(5) We conclude that both exogenously applied PAF by inhalation and antigen exposure are capable of inducing LAR in sensitized guinea pigs, and thus the priming effect of immunization and PAF may contribute to the development of LAR observed in asthma.
(6) The effect of ipratropium bromide administered at two dosage levels, 40 and 80 mug, isoproterenol, 150 mug, and placebo using a metered dose inhaler was evaluated in ten adult patients with asthma in a double-blind, crossover study.
(7) Relative to the perceived severity of their asthma, both Maoris and Pacific Islanders lost more time from work or school and used hospital services more than European asthmatics using A & E. The increased use of A & E by Maori and Pacific Island asthmatics seemed not attributable to the intrinsic severity of their asthma and was better explained by ethnic, socioeconomic and sociocultural factors.
(8) We repeat our call for them to do so at the earliest opportunity, and to share those findings so that we can take any appropriate actions.” In the BBC programme the 29-year-old Rupp, who won 10,000m silver at the London 2012 Olympics behind Farah, was accused of having taken testosterone and being a regular user of the asthma drug prednisone, which is banned in competition.
(9) In 20 adult patients with asthma, we evaluated bronchodilation to a single administration of metered-dose glycopyrrolate aerosol (GA) to ascertain its onset and duration of action along with evaluation of safety.
(10) While much research has examined the aetiology and treatment of asthma, little work has been done on its social impact.
(11) There was no statistical difference between atopic children with asthma and those with allergic rhinitis as compared with an age-matched control population of 20 non-atopic children in terms of levels of active T lymphocytes or total T lymphocytes.
(12) This dose is safe and efficient in the maintenance treatment of childhood asthma.
(13) Indicators of the blood kinin system were studied in 57 persons including 42 patients with asthma and 15 healthy persons (control group) in the Kislovodsk health resort area.
(14) Poor workplace health and safety, inadequate toilet facilities and dangerous fumes from mosquito fogging that led to one asylum seeker with asthma collapsing were all raised as concerns by Kilburn, although he stressed that he believed G4S management and expatriate G4S staff acted appropriately.
(15) Two patients died from asthma after leaving our service, one patient having left the hospital against medical advice with arterial blood gases demonstrating acute respiratory acidosis during status asthmaticus.
(16) The findings of respiratory and sensitivity tests suggest: (i) that passive smoking may trigger asthma attacks in subjects who suffer from asthma and (ii) that the airways of such subjects show increased histamine reactivity four hours after the passive smoke exposure.
(17) The circumstances surrounding 142 hospital admissions for acute asthma in 110 children during a one year period were examined.
(18) Breathing pattern was no more variable during severe asthma than during recovery.
(19) There is a need for further education of health professionals in the appropriate assessment, documentation and treatment of asthma in children.
(20) For pollen asthma, six studies conclude that there were superior results with desensitization than to placebo.
Chitin
Definition:
(n.) A white amorphous horny substance forming the harder part of the outer integument of insects, crustacea, and various other invertebrates; entomolin.
Example Sentences:
(1) The effect of O-(carboxymethyl)chitins (CM-chitins) on the activation of mouse-peritoneal macrophages in vivo and their mitogenic activity on mouse spleen-cells were investigated.
(2) The pH activity profile, cofactor requirements, and kinetic parameters of the endogenously activated chitin synthase were identical to those of the trypsin-activated enzyme in protoplast membranes.
(3) Results obtained from isotopic dilution experiments are consistent with the operation of the chitin pathway as it has been established in fungal preparations.
(4) The significance of these results is discussed in connection with the mechanism of chitin synthesis and cell wall morphogenesis in S. cerevisiae.
(5) Here we show that the nodulation genes of this bacterium determine the production of a large family of Nod-factors which are N-acylated chitin pentamers carrying a variety of substituents.
(6) In a permeabilized-cell assay, Oct-Gln-UPOC had a 10-fold-lower inhibitory activity toward chitin synthetase than did the Oct-Lys-UPOC analog.
(7) The preparation yielded an apparent Km of 3.9 mg chitin ml-1 [17.6 mM-N-acetylglucosamine (GlcNAc) equivalents] and V of 2.3 nmol GlcNAc formed min-1 (mg protein)-1.
(8) In the case of the [14C]chitin synthesized, which does not show inhibition by alpha factor, the lowering of the specific activity of the precursor is exactly compensated for by an increased rate of chitin synthesis caused by alpha factor.
(9) Chitin derivatives are also used in things like contact lens, surgical stitches and artificial skin.
(10) The inhibitor was effective against crude or purified (chitosome) preparations of chitin synthetase.
(11) After 3 h incubation with tioconazole, 1 microgram ml-1, the incorporation of the radiolabelled glucose into chitin of intact cells and regenerating spheroplasts of C. albicans was inhibited by 43% and 30%, respectively.
(12) Electron microscopy has revealed that chitin from a representative selection of insect orders (plus one crustacean and one arachnid) is localized in crystallites about 2.8 nm across.
(13) When dividing cells of Saccharomyces cerevisiae were exposed to the polysaccharide-binding dye Congo red, the walls and septa became sites of chitin accumulation.
(14) Partially O-hydroxyethylated chitin (glycol chitin) was used as a substrate in the purification and characterization of this enzyme.
(15) In view of the small molecular size and high lipid solubility of methyl mercury and the lipophilic properties of the chitin-protein exoskeleton of the lobster, it is likely that significant uptake directly from the water as well as storage of absorbed methyl mercury occurred in the tail region.
(16) This confirmed that S. pombe cell wall is devoid of chitin.
(17) Adjuvant activity of chitin derivatives was examined in guinea-pigs and mice.
(18) DFB inhibits chitin synthesis and growth of imaginal epidermis in insects and suppresses melanogenesis and uptake of nucleosides in mouse melanoma cells, but the means of cell growth regulation and the role of metabolism of DFB in such regulation have not been established.
(19) These microfibers have a diameter of 80 A and may consist of chitin crystallites surrounded by a matrix coat.
(20) Chemical analysis of adult females of Onchocerca gibsoni gave estimated chitin contents of 200-500 micrograms (g dry weight)-1.